Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 1, 2012, Pages 82-90

  Tomitori, Hideyuki ^a   Suganami, Akiko ^b   Saiki, Ryotaro ^b   Mizuno, Satomi ^b   Yoshizawa, Yuki ^b   Masuko, Takashi ^c   Tamura, Yutaka ^b   Nishimura, Kazuhiro ^b   Toida, Toshihiko ^b   Williams, Keith ^d   Kashiwagi, Keiko ^a   Igarashi, Kazuei ^b  

^a CHIBA INSTITUTE OF SCIENCE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c NIHON UNIVERSITY   (Japan)

^d SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMIC ACID; HETERODIMER; HISTIDINE; IFENPRODIL; LYSINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENYLALANINE; SPERMINE; THREONINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RAT; RECEPTOR BINDING; RECEPTOR UPREGULATION; WESTERN BLOTTING; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; FEMALE; MOLECULAR SEQUENCE DATA; PIPERIDINES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMINE; XENOPUS LAEVIS;

EID: 84866334439     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.192286     Document Type: Article

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