Paracoccidioides brasiliensis induces secretion of IL-6 and IL-8 by lung epithelial cells. Modulation of host cytokine levels by fungal proteases

Microbes and Infection

Volumn 14, Issue 12, 2012, Pages 1077-1085

  Maza, Paloma K ^a   Oliveira, Priscila ^a   Toledo, Marcos S ^a   Paula, Daisy M B ^a   Takahashi, Helio K ^a   Straus, Anita H ^a   Suzuki, Erika ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cytokines; Epithelial cells; MAPK ERK kinases; P38 MAPK; Paracoccidioides brasiliensis; Proteases

Indexed keywords

APROTININ; FORMALDEHYDE; FUNGAL ENZYME; GAMMA INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEINASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; HOST; HUMAN; HUMAN CELL; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PARACOCCIDIOIDES BRASILIENSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

CELL LINE; EPITHELIAL CELLS; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-6; INTERLEUKIN-8; MITOGEN-ACTIVATED PROTEIN KINASES; PARACOCCIDIOIDES; PEPTIDE HYDROLASES; PROTEOLYSIS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

FUNGI; PARACOCCIDIOIDES BRASILIENSIS;

EID: 84866325768     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2012.05.016     Document Type: Article

References (43)

1. Colombo A.L., Tobón A., Restrepo A., Queiroz-Telles F., Nucci M. Epidemiology of endemic systemic fungal infections in Latin America. Med. Mycol. 2011, 49:785-798.
2. Martinez R. Paracoccidioidomycosis: the dimension of the problem of a neglected disease. Rev. Soc. Bras. Med. Trop. 2010, 43:480.
3. Ameen M., Talhari C., Talhari S. Advances in paracoccidioidomycosis. Clin. Exp. Dermatol. 2010, 35:576-580.
4. Wanke B., Aidê M.A. Chapter 6 - paracoccidioidomycosis. J. Bras. Pneumol. 2009, 35:1245-1249.
5. Suzuki T., Chow C.W., Downey G.P. Role of innate immune cells and their products in lung immunopathology. Int. J. Biochem. Cell Biol. 2008, 40:1348-1361.
6. Proud D., Leigh R. Epithelial cells and airway diseases. Immunol. Rev. 2011, 242:186-204.
7. Chang B., Amemura-Maekawa J., Kura F., Kawamura I., Watanabe H. Expression of IL-6 and TNF-alpha in human alveolar epithelial cells is induced by invading, but not by adhering, Legionella pneumophila. Microb. Pathog. 2004, 37:295-302.
8. Yang J., Hooper W.C., Phillips D.J., Talkington D.F. Regulation of proinflammatory cytokines in human lung epithelial cells infected with Mycoplasma pneumoniae. Infect. Immun. 2002, 70:3649-3655.
9. Sharma M., Sharma S., Roy S., Varma S., Bose M. Pulmonary epithelial cells are a source of interferon-gamma in response to Mycobacterium tuberculosis infection. Immunol. Cell Biol. 2007, 85:229-237.
10. Naglik J.R., Moyes D. Epithelial cell innate response to Candida albicans. Adv. Dent. Res. 2011, 23:50-55.
11. Balloy V., Sallenave J.M., Wu Y., Touqui L., Latgé J.P., Si-Tahar M., Chignard M. Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway. J. Biol. Chem. 2008, 283:30513-30521.
12. Chiu L.L., Perng D.W., Yu C.H., Su S.N., Chow L.P. Mold allergen, pen C 13, induces IL-8 expression in human airway epithelial cells by activating protease-activated receptor 1 and 2. J. Immunol. 2007, 178:5237-5244.
13. Schmeck B., N'Guessan P.D., Ollomang M., Lorenz J., Zahlten J., Opitz B., Flieger A., Suttorp N., Hippenstiel S. Legionella pneumophila-induced NF-kappaB- and MAPK-dependent cytokine release by lung epithelial cells. Eur. Respir. J. 2007, 29:25-33.
14. Carmona E.M., Lamont J.D., Xue A., Wylam M., Limper A.H. Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells. Respir. Res. 2010, 11:95.
15. Khan K., Konar M., Goyal A., Ghosh S. Enteroaggregative Escherichia coli infection induces IL-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappaB and AP-1 in INT-407 cells. Mol. Cell. Biochem. 2010, 337:17-24.
16. Grenier D., La V.D. Proteases of Porphyromonas gingivalis as important virulence factors in periodontal disease and potential targets for plant-derived compounds: a review article. Curr. Drug Targets 2011, 12:322-331.
17. Yike I. Fungal proteases and their pathophysiological effects. Mycopathologia 2011, 171:299-323.
18. Maza P.K., Straus A.H., Toledo M.S., Takahashi H.K., Suzuki E. Interaction of epithelial cell membrane rafts with Paracoccidioides brasiliensis leads to fungal adhesion and Src-family kinase activation. Microbes Infect. 2008, 10:540-547.
19. Ywazaki C.Y., Maza P.K., Suzuki E., Takahashi H.K., Straus A.H. Role of host glycosphingolipids on Paracoccidioides brasiliensis adhesion. Mycopathologia 2011, 171:325-332.
20. Schägger H. Tricine-SDS-PAGE. Nat. Protoc. 2006, 1:16-22.
21. Reihill J.A., Moore J.E., Elborn J.S., Ennis M. Effect of Aspergillus fumigatus and Candida albicans on pro-inflammatory response in cystic fibrosis epithelium. J. Cyst. Fibros. 2011, 10:401-406.
22. Mendes-Giannini M.J., Hanna S.A., da Silva J.L., Andreotti P.F., Vincenzi L.R., Benard G., Lenzi H.L., Soares C.P. Invasion of epithelial mammalian cells by Paracoccidioides brasiliensis leads to cytoskeletal rearrangement and apoptosis of the host cell. Microbes Infect. 2004, 6:882-891.
23. Shimohata T., Nakano M., Lian X., Shigeyama T., Iba H., Hamamoto A., Yoshida M., Harada N., Yamamoto H., Yamato M., Mawatari K., Tamaki T., Nakaya Y., Takahashi A. Vibrio parahaemolyticus infection induces modulation of IL-8 secretion through dual pathway via VP1680 in Caco-2 cells. J. Infect. Dis. 2011, 203:537-544.
24. Ju C.H., Chockalingam A., Leifer C.A. Early response of mucosal epithelial cells during Toxoplasma gondii infection. J. Immunol. 2009, 183:7420-7427.
25. Huang G., Shi L.Z., Chi H. Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination. Cytokine 2009, 48:161-169.
26. Zhang Y., Dong C. Regulatory mechanisms of mitogen-activated kinase signaling. Cell. Mol. Life Sci. 2007, 64:2771-2789.
27. Dahan S., Busuttil V., Imbert V., Peyron J.F., Rampal P., Czerucka D. Enterohemorrhagic Escherichia coli infection induces interleukin-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappaB and AP-1 in T84 cells. Infect. Immun. 2002, 70:2304-2310.
28. Mallory J.C., Craven R.J. Candida albicans Dap1p promotes ergosterol synthesis via the P450 protein Erg11p/Cyp51p, regulating susceptibility to azole antifungal drugs, morphogenesis and damage resistance. Pharmacologia 2012, 3:179-189.
29. Woolley C.M., Nielsen-Preiss S.M., Hyman L.E. The response of Candida albicans to simulated microgravity. Gravit. Space Biol. Bull. 2010, 23:93-94.
30. Galán-Díez M., Arana D.M., Serrano-Gómez D., Kremer L., Casasnovas J.M., Ortega M., Cuesta-Domínguez A., Corbí A.L., Pla J., Fernández-Ruiz E. Candida albicans beta-glucan exposure is controlled by the fungal CEK1-mediated mitogen-activated protein kinase pathway that modulates immune responses triggered through dectin-1. Infect. Immun. 2010, 78:1426-1436.
31. Crabtree J.E., Farmery S.M., Lindley I.J., Figura N., Peichl P., Tompkins D.S. CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J. Clin. Pathol. 1994, 47:945-950.
32. Kim J.S., Ryu M.J., Byun E.H., Kim W.S., Whang J., Min K.N., Shong M., Kim H.J., Shin S.J. Differential immune response of adipocytes to virulent and attenuated Mycobacterium tuberculosis. Microbes Infect. 2011, 13:1242-1251.
33. Parmely M., Gale A., Clabaugh M., Horvat R., Zhou W.W. Proteolytic inactivation of cytokines by Pseudomonas aeruginosa. Infect. Immun. 1990, 58:3009-3014.
34. Fletcher J., Reddi K., Poole S., Nair S., Henderson B., Tabona P., Wilson M. Interactions between periodontopathogenic bacteria and cytokines. J. Periodontal Res. 1997, 32:200-205.
35. Wilson M., Seymour R., Henderson B. Bacterial perturbation of cytokine networks. Infect. Immun. 1998, 66:2401-2409.
36. Turner C.E., Kurupati P., Jones M.D., Edwards R.J., Sriskandan S. Emerging role of the interleukin-8 cleaving enzyme SpyCEP in clinical Streptococcus pyogenes infection. J. Infect. Dis. 2009, 200:555-563.
37. Okuda J., Hayashi N., Tanabe S., Minagawa S., Gotoh N. Degradation of interleukin 8 by the serine protease MucD of Pseudomonas aeruginosa. J. Infect. Chemother. 2011, 17:782-792.
38. Behrensdorf-Nicol H.A., Kegel B., Bonifas U., Silberbach K., Klimek J., Weiber K., Krämer B. Residual enzymatic activity of the tetanus toxin light chain present in tetanus toxoid batches used for vaccine production. Vaccine 2008, 26:3835-3841.
39. Cryz S.J., Friedman R.L., Pavlovskis O.R., Iglewski B.H. Effect of formalin toxoiding on Pseudomonas aeruginosa toxin A: biological, chemical, and immunochemical studies. Infect. Immun. 1981, 32:759-768.
40. Thaysen-Andersen M., Jørgensen S.B., Wilhelmsen E.S., Petersen J.W., Højrup P. Investigation of the detoxification mechanism of formaldehyde-treated tetanus toxin. Vaccine 2007, 25:2213-2227.
41. Lopera D., Naranjo T.W., Cruz O.G., Restrepo A., Cano L.E., Lenzi H.L. Structural and topographic dynamics of pulmonary histopathology and local cytokine profiles in Paracoccidioides brasiliensis conidia-infected mice. PLoS Negl. Trop. Dis. 2011, 5:e1232.
42. Mukaida N. Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. Am. J. Physiol. Lung Cell Mol. Physiol. 2003, 284:L566-L577.
43. Jones S.A. Directing transition from innate to acquired immunity: defining a role for IL-6. J. Immunol. 2005, 175:3463-3468.