A new class of selective and potent 7-dehydrocholesterol reductase inhibitors

Journal of Medicinal Chemistry

Volumn 55, Issue 17, 2012, Pages 7614-7622

  Horling, Aline ^a   Müller, Christoph ^b   Barthel, Richard ^a   Bracher, Franz ^b   Imming, Peter ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 [2 (3,4 DIMETHOXYPHENYL)ETHYL] 6 HYDROXY 7 METHOXY 1,2,3,4 TETRAHYDROISOQUINOLINE; 2 [2 (4 CHLOROPHENYL)ETHYL] 6 HYDROXY 7 METHOXY 1,2,3,4 TETRAHYDROISOQUINOLINE; BERBERINE DERIVATIVE; ENZYME INHIBITOR; ERGOSTEROL; LANOSTEROL; PHENETHYLTETRAHYDROISOQUINOLINE; QUINOLINE DERIVATIVE; SQUALENE; UNCLASSIFIED DRUG; ZYMOSTENOL;

ARTICLE; BACTERIUM; BIOSYNTHESIS; CATALYSIS; CHOLESTEROL SYNTHESIS; DRUG CYTOTOXICITY; DRUG STRUCTURE; ENZYME INHIBITION; FUNGUS; HUMAN; HUMAN CELL; IC 50; PATHOGENESIS; SMITH LEMLI OPITZ SYNDROME; WHOLE CELL;

ENZYME INHIBITORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84866315186     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3006096     Document Type: Article

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