The Prothrombotic Phenotypes in Familial Protein C Deficiency Are Differentiated by Computational Modeling of Thrombin Generation

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Brummel Ziedins, Kathleen E ^a   Orfeo, Thomas ^a   Callas, Peter W ^c   Gissel, Matthew ^a   Mann, Kenneth G ^a   Bovill, Edwin G ^b  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c University of Vermont   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTHROMBIN; THROMBIN;

ARTICLE; BLOOD ANALYSIS; BLOOD CLOTTING; BLOOD CLOTTING TIME; BLOOD COMPONENT; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DISEASE PREDISPOSITION; FEMALE; GENE MUTATION; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; MEDICAL HISTORY; PHENOTYPE; PROTEIN C DEFICIENCY; SEX DIFFERENCE; SIGNAL TRANSDUCTION; THROMBOSIS;

AREA UNDER CURVE; BLOOD COAGULATION TESTS; COMPUTER SIMULATION; FEMALE; HOMOZYGOTE; HUMANS; MALE; MODELS, BIOLOGICAL; MODELS, THEORETICAL; PHENOTYPE; POLYMORPHISM, GENETIC; PROTEIN C DEFICIENCY; PROTHROMBIN; SEX FACTORS; THROMBIN; THROMBOSIS;

EID: 84866307931     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044378     Document Type: Article

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