Genome-wide association study for T lymphocyte subpopulations in swine

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  Lu, Xin ^a,b   Fu, Wei Xuan ^a,c   Luo, Yan Ru ^a   Ding, Xiang Dong ^a   Zhou, Jia Peng ^a   Liu, Yang ^a   Liu, Jian Feng ^a   Zhang, Qin ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

Genome wide association study; Swine; T lymphocyte subpopulations

Indexed keywords

CLASSICAL SWINE FEVER VACCINE; UNCLASSIFIED DRUG; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CD4 CD8 RATIO; CLASSICAL SWINE FEVER; CONTROLLED STUDY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC IMPROVEMENT; GENETIC REGULATION; GENETIC VARIABILITY; GENOTYPE; IMMUNE STATUS; NONHUMAN; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SWINE; T LYMPHOCYTE SUBPOPULATION; ANIMAL; BIOLOGICAL MODEL; GENETICS; GENOTYPING TECHNIQUE; IMMUNOLOGY; LYMPHOCYTE SUBPOPULATION; T LYMPHOCYTE;

SUIDAE;

ANIMALS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; LYMPHOCYTE SUBSETS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; SWINE; T-LYMPHOCYTES;

EID: 84866274936     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-488     Document Type: Article

References (44)

1. Visscher AH, Janss LL, Niewold TA, de Greef KH. Disease incidence and immunological traits for the selection of healthy pigs. A review. Vet Q 2002, 24(1):29-34.
2. Alving K. Airways vasodilatation in the immediate allergic reaction. Involvement of inflammatory mediators and sensory nerves. Acta Physiol Scand Suppl 1991, 597:1-64.
3. Kenmochi T, Mullen Y, Miyamoto M, Stein E. Swine as an Allotransplantation Model. Vet Immunol Immunop 1994, 43(1-3):177-183.
4. Misfeldt ML, Grimm DR. Sinclair Miniature Swine - an Animal-Model of Human-Melanoma. Vet Immunol Immunop 1994, 43(1-3):167-175.
5. Doyle C, Strominger JL. Interaction between CD4 and Class II MHC Molecules Mediates Cell Adhesion (Reprinted from Nature, vol 330, pg 256-259, 1987). J Immunol 2010, 184(11):5935-5938.
6. Regueiro JR, Rodríguez-Gallego C, Arnaiz-Villena A. Human T-lymphocyte activation deficiencies 1994, R.G. Landes; CRC Press distributor, Austin, TX Boca Raton, FL.
7. Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003, 300(5617):337-339. 10.1126/science.1082305, 12690201.
8. Swain SL, Dutton RW, Schwab R, Yamamoto J. Xenogeneic Human Anti-Mouse T-Cell Responses Are Due to the Activity of the Same Functional T-Cell Subsets Responsible for Allospecific and Major Histocompatibility Complex-Restricted Responses. J Exp Med 1983, 157(2):720-729. 10.1084/jem.157.2.720, 2186928, 6185618.
9. Doherty PC, Topham DJ, Tripp RA. Establishment and persistence of virus-specific CD4(+) and CD8(+) T cell memory. Immunol Rev 1996, 150:23-44. 10.1111/j.1600-065X.1996.tb00694.x, 8782700.
10. Ober BT, Summerfield A, Mattlinger C, Wiesmuller KH, Jung G, Pfaff E, Saalmuller A, Rziha HJ. Vaccine-induced, pseudorabies virus-specific, extrathymic CD4(+)CD8(+) memory T-helper cells in swine. J Virol 1998, 72(6):4866-4873. 110037, 9573253.
11. Damoiseaux JG, Cautain B, Bernard I, Mas M, van Breda Vriesman PJ, Druet P, Fournie G, Saoudi A. A dominant role for the thymus and MHC genes in determining the peripheral CD4/CD8 T cell ratio in the rat. J Immunol 1999, 163(6):2983-2989.
12. Gerner W, Käser T, Saalmüller A. Porcine T lymphocytes and NK cells-an update. Dev Comp Immunol 2009, 33(3):310-320. 10.1016/j.dci.2008.06.003, 18601948.
13. Dwivedi V, Manickam C, Binjawadagi B, Linhares D, Murtaugh M, Renukaradhya G. Evaluation of immune responses to porcine reproductive and respiratory syndrome virus in pigs during early stage of infection under farm conditions. Virol J 2012, 16(9):45.
14. Armengol E, Wiesmüller K, Wienhold D, Büttner M, Pfaff E, Jung G, Saalmüller A. Identification of T-cell epitopes in the structural and non-structural proteins of classical swine fever virus. J Gen Virol 2002, 83(Pt 3):551-560.
15. Rau H, Revets H, Balmelli C, McCullough K, Summerfield A. Immunological properties of recombinant classical swine fever virus NS3 protein in vitro and in vivo. Vet Res 2006, 37(1):155-168. 10.1051/vetres:2005049, 16336932.
16. Kimman T, DeBruin T, Voermans J, Bianchi A. Cell-mediated immunity to pseudorabies virus: cytolytic effector cells with characteristics of lymphokine-activated killer cells lyse virus-infected and glycoprotein gB- and gC-transfected L14 cells. J Gen Virol 1996, 77(Pt 5):987-990.
17. Bianchi A, Moonen-Leusen H, Van Milligen F, Savelkoul H, Zwart R, Kimman T. A mouse model to study immunity against pseudorabies virus infection: significance of CD4+ and CD8+ cells in protective immunity. Vaccine 1998, 16(16):1550-1558. 10.1016/S0264-410X(98)00044-9, 9711803.
18. Carr MM, Howard CJ, Sopp P, Manser JM, Parsons KR. Expression on Porcine Gamma-Delta Lymphocytes of a Phylogenetically Conserved Surface-Antigen Previously Restricted in Expression to Ruminant Gamma-Delta T-Lymphocytes. Immunology 1994, 81(1):36-40. 1422288, 8132217.
19. Hirt W, Saalmuller A, Reddehase MJ. Distinct Gamma-Delta-T-Cell Receptors Define 2 Subsets of Circulating Porcine Cd2-Cd4-Cd8- Lymphocytes-T. Eur J Immunol 1990, 20(2):265-269. 10.1002/eji.1830200206, 1690131.
20. Saalmuller A, Hirt W, Reddehase MJ. Porcine Gamma-Sigma-Lymphocyte-T Subsets Differing in Their Propensity to Home to Lymphoid-Tissue. Eur J Immunol 1990, 20(10):2343-2346. 10.1002/eji.1830201026, 1978711.
21. Pescovitz MD, Lunney JK, Sachs DH. Murine Anti-Swine T4 and T8 Monoclonal-Antibodies - Distribution and Effects on Proliferative and Cyto-Toxic T-Cells. J Immunol 1985, 134(1):37-44.
22. Saalmuller A, Reddehase MJ, Buhring HJ, Jonjic S, Koszinowski UH. Simultaneous Expression of Cd4 and Cd8 Antigens by a Substantial Proportion of Resting Porcine Lymphocytes-T. Eur J Immunol 1987, 17(9):1297-1301. 10.1002/eji.1830170912, 2958295.
23. Summerfield A, Rziha HJ, Saalmuller A. Functional characterization of porcine CD4(+)CD8(+) extrathymic T lymphocytes. Cell Immunol 1996, 168(2):291-296. 10.1006/cimm.1996.0078, 8640877.
24. De Bruin T, Van Rooij E, De Visser Y, Bianchi A. Cytolytic function for pseudorabies virus-stimulated porcine CD4+ CD8dull+ lymphocytes. Viral Immunol 2000, 13(4):511-520. 10.1089/vim.2000.13.511, 11192298.
25. Xu Y, Cui L, Tian C, Zhang G, Huo G, Tang L, Li Y. Immunogenicity of recombinant classic swine fever virus CD8(+) T lymphocyte epitope and porcine parvovirus VP2 antigen coexpressed by Lactobacillus casei in swine via oral vaccination. Clin Vaccine Immunol 2011, 18(11):1979-1986. 10.1128/CVI.05204-11, 3209017, 21940406.
26. Wattrang E, Almqvist M, Johansson A, Fossum C, Wallgren P, Pielberg G, Andersson L, Edfors-Lilja I. Confirmation of QTL on porcine chromosomes 1 and 8 influencing leukocyte numbers, haematological parameters and leukocyte function. Anim Genet 2005, 36(4):337-345. 10.1111/j.1365-2052.2005.01315.x, 16026345.
27. Lu X, Liu J-F, Gong Y-F, Wang Z-P, Liu Y, Zhang Q. Mapping quantitative trait loci for T lymphocyte subpopulations in peripheral blood in swine. BMC Genet 2011, 12:79. 3182951, 21923905.
28. Andersson L. Genome-wide association analysis in domestic animals: a powerful approach for genetic dissection of trait loci. Genetica 2009, 136(2):341-349. 10.1007/s10709-008-9312-4, 18704695.
29. Ramos AM, Crooijmans RPMA, Affara NA, Amaral AJ, Archibald AL, Beever JE, Bendixen C, Churcher C, Clark R, Dehais P, et al. Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology. PLoS One 2009, 4(8):e6524. 10.1371/journal.pone.0006524, 2716536, 19654876.
30. Duijvesteijn N, Knol EF, Merks JWM, Crooijmans RPMA, Groenen MAM, Bovenhuis H, Harlizius B. A genome-wide association study on androstenone levels in pigs reveals a cluster of candidate genes on chromosome 6. BMC Genet 2010, 11:42. 2889844, 20487517.
31. Fan B, Onteru S, Du Z, Garrick D, Stalder K, Rothschild M. Genome-wide association study identifies Loci for body composition and structural soundnesstraits in pigs. PLoS One 2011, 6(2):e14726. 10.1371/journal.pone.0014726, 3044704, 21383979.
32. Ramos A, Crooijmans R, Affara N, Amaral A, Archibald A, Beever J, Bendixen C, Churcher C, Clark R, Dehais P, et al. Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology. PLoS One 2009, 4(8):e6524. 10.1371/journal.pone.0006524, 2716536, 19654876.
33. Browning BL, Browning SR. A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet 2009, 84(2):210-223. 10.1016/j.ajhg.2009.01.005, 2668004, 19200528.
34. Kalinowski ST, Taper ML, Marshall TC. Revising how the computer program CERVUS accommodates genotyping error increases success in paternity assignment. Mol Ecol 2007, 16(5):1099-1106. 10.1111/j.1365-294X.2007.03089.x, 17305863.
35. Jiang L, Liu J, Sun D, Ma P, Ding X, Yu Y, Zhang Q. Genome wide association studies for milk production traits in Chinese Holstein population. PLoS One 2010, 5(10):e13661. 10.1371/journal.pone.0013661, 2965099, 21048968.
36. Pearson TA, Manolio TA. How to interpret a genome-wide association study. Jama-J Am Med Assoc 2008, 299(11):1335-1344.
37. Barrett J, Fry B, Maller J, Daly M. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21(2):263-265. 10.1093/bioinformatics/bth457, 15297300.
38. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M. The structure of haplotype blocks in the human genome. Science 2002, 296(5576):2225-2229. 10.1126/science.1069424, 12029063.
39. Amadori A, Zamarchi R, Chieco-Bianchi L. CD4: CD8 ratio and HIV infection: the " tap-and-drain" hypothesis. Immunol Today 1996, 17:414-417. 10.1016/0167-5699(96)10049-9, 8854558.
40. Evans DM, Frazer IH, Martin NG. Genetic and environmental causes of variation in basal levels of blood cells. Twin Res 1999, 2:250-257.
41. Hall MA, Ahmadi KA, Norman P, Snieder H, Macgregor A, Vaughan RW, Spector TD, Lanchbury JS. Genetic influence on peripheral blood T lymphocyte levels. Genes Immun 2000, 1:423-427. 10.1038/sj.gene.6363702, 11196672.
42. Reiner G, Fischer R, Hepp S, Berge T, Kohler F, Willems H. Quantitative trait loci for white blood cell numbers in swine. Anim Genet 2008, 39(2):163-168. 10.1111/j.1365-2052.2008.01700.x, 18307579.
43. Edfors-Lilja I, Wattrang E, Marklund L, Moller M, Andersson-Eklund L, Andersson L, Fossum C. Mapping quantitative trait loci for immune capacity in the pig. J Immunology 1998, 160:829-835.
44. Edfors-Lilja I, Wattrang E, Andersson L, Fossum C. Mapping quantitative trait loci for stress induced alterations in porcine leukocyte numbers and functions. Anim Genet 2000, 31:186-193. 10.1046/j.1365-2052.2000.00628.x, 10895309.