Evaluation of a microfluidics-based platform and slab electrophoresis for determination of size, integrity and quantification of in vitro transcribed RNA used as a component in therapeutic drug manufacturing

Journal of Pharmaceutical and Biomedical Analysis

Volumn 70, Issue , 2012, Pages 657-663

  Slagter Jäger, Jacoba Grietje ^a   Nicolette, Charles A ^a   Tcherepanova, Irina Y ^a  

^a Argos Therapeutics Inc   (United States)

Author keywords

Bioanalyzer; Denaturing agarose gel; Integrity; Quantification; RNA; Size

Indexed keywords

RNA;

ACCURACY; AGAR GEL ELECTROPHORESIS; ANALYZER; ARTICLE; CONTROLLED STUDY; DRUG MANUFACTURE; ELECTROPHORESIS; IN VITRO STUDY; MICROFLUIDICS; MOLECULAR SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; RNA ANALYSIS; RNA STRUCTURE; RNA TRANSCRIPTION; SLAB ELECTROPHORESIS;

BIOTECHNOLOGY; ELECTROPHORESIS, AGAR GEL; ELECTROPHORESIS, MICROCHIP; MICROFLUIDIC ANALYTICAL TECHNIQUES; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; RIBONUCLEOTIDES; RNA; SPECTROPHOTOMETRY; TRANSCRIPTION, GENETIC;

EID: 84866254481     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.04.031     Document Type: Article

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