Srp20 regulates TrkB pre-mRNA splicing to generate TrkB-Shc transcripts with implications for Alzheimer's disease

Journal of Neurochemistry

Volumn 123, Issue 1, 2012, Pages 159-171

  Wong, Jenny ^a   Garner, Brett ^a   Halliday, Glenda M ^b,c   Kwok, John B J ^b,c  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Alzheimer's Disease; amyloid beta; BDNF; exon splicing; Srp20; TrkB

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; PROTEIN SHC; SERINE ARGININE PROTEIN 20; SERINE ARGININE RICH PROTEIN; TROPOMYOSIN; TROPOMYOSIN RECEPTOR KINASE B; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; BINDING SITE; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRON; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; REAL TIME POLYMERASE CHAIN REACTION; RNA SPLICING; SERINE ARGININE PROTEIN 20 GENE; TRANSIENT TRANSFECTION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANALYSIS OF VARIANCE; BINDING SITES; BRAIN; CELL LINE, TUMOR; EXONS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MICROARRAY ANALYSIS; NEUROBLASTOMA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTOR, TRKB; RNA PRECURSORS; RNA SPLICING; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; TRANSCRIPTOME;

EID: 84866247986     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07873.x     Document Type: Article

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