An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia

Gene

Volumn 485, Issue 2, 2011, Pages 130-138

  Wang, Yan ^a   Wang, Junning ^a   Gao, Lei ^a   Stamm, Stefan ^b   Andreadis, Athena ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alternative splicing regulation; Exon 10 and tangle dementia; Heterogeneous nuclear ribonucleoproteins g and e2; Isoform ratios; MAP tau; Splicing factor srP75

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN E2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN G; PROTEIN; RNA; SPLICING FACTOR SRP75; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXON; FRONTOTEMPORAL DEMENTIA; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTRON; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE;

ALTERNATIVE SPLICING; ALZHEIMER DISEASE; ANIMALS; BASE SEQUENCE; BRAIN; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; EXONS; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION REGULATION; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; IMMUNOPRECIPITATION; INTRONS; MOLECULAR SEQUENCE DATA; NEURONS; PARKINSONIAN DISORDERS; RNA SPLICE SITES; RNA-BINDING PROTEINS; SEQUENCE ANALYSIS, DNA; TAU PROTEINS; TAUOPATHIES;

RODENTIA;

EID: 80052031413     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2011.06.020     Document Type: Article

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