Optimization of the lyophilization process for long-term stability of solidlipid nanoparticles

Drug Development and Industrial Pharmacy

Volumn 38, Issue 10, 2012, Pages 1270-1279

  Howard, Melissa D ^a   Lu, Xiuling ^b   Jay, Michael ^c   Dziubla, Thomas D ^d  

^a University of Kentucky   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNC Hamner Institute for Drug Safety Sciences   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Drug loading; Lyoprotectant; Particle size; Storage; Sucrose

Indexed keywords

DEXAMETHASONE; DIETHANOLAMINE; FRUCTOSE; GLUCOSE; LACTOSE; MACROGOL 6000; MALTOSE; MANNOSE; OCTADECANOL; PALMITIC ACID; POLYOXYETHYLENE STEARYL ETHER; POLYSORBATE 60; POLYVINYL ALCOHOL; POVIDONE; POVIDONE K 30; SOLID LIPID NANOPARTICLE; SUCROSE; TREHALOSE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; HUMIDITY; PARTICLE SIZE; PHYSICAL CHEMISTRY; STORAGE TEMPERATURE; SUSPENSION;

DEXAMETHASONE; DRUG STABILITY; FREEZE DRYING; LIPIDS; NANOPARTICLES; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; SUSPENSIONS; TEMPERATURE; WATER;

EID: 84866245751     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.645835     Document Type: Article

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