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Volumn 22, Issue 10, 2012, Pages 973-980

Anesthetics and the developing brain: Time for a change in practice? A pro/con debate

Author keywords

anesthesia; cognitive deficit; development; neurotoxicity; newborn

Indexed keywords

4 AMINOBUTYRIC ACID; ANESTHETIC AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER;

EID: 84866241727     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/pan.12015     Document Type: Review
Times cited : (41)

References (56)
  • 1
    • 77049157029 scopus 로고
    • Relationship of anesthesia to postoperative personality changes in children
    • Eckenhoff JE,. Relationship of anesthesia to postoperative personality changes in children. Am J Dis Child 1953; 86: 587-591.
    • (1953) Am J Dis Child , vol.86 , pp. 587-591
    • Eckenhoff, J.E.1
  • 3
    • 0034635370 scopus 로고    scopus 로고
    • Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome
    • DOI 10.1126/science.287.5455.1056
    • Ikonomidou C, Bittigau P, Ishimaru MJ, et al,. Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 2000; 287: 1056-1060. (Pubitemid 30094364)
    • (2000) Science , vol.287 , Issue.5455 , pp. 1056-1060
    • Ikonomidou, C.1    Bittigau, P.2    Koch, C.3    Genz, K.4    Stefovska, V.5    Horster, F.6
  • 5
    • 3342981276 scopus 로고    scopus 로고
    • Anesthetic neurotoxicity: The collision between laboratory neuroscience and clinical medicine
    • DOI 10.1097/00000542-200408000-00003
    • Todd MM,. Anesthetic neurotoxicity: the collision between laboratory neuroscience and clinical medicine. Anesthesiology 2004; 101: 272-273. (Pubitemid 38988478)
    • (2004) Anesthesiology , vol.101 , Issue.2 , pp. 272-273
    • Todd, M.M.1
  • 6
    • 3342957149 scopus 로고    scopus 로고
    • Anesthetic agents and the immature brain: Are these toxic or therapeutic?
    • DOI 10.1097/00000542-200408000-00033
    • Anand KJ, Soriano SG,. Anesthetic agents and the immature brain: are these toxic or therapeutic? Anesthesiology 2004; 101: 527-530. (Pubitemid 38988508)
    • (2004) Anesthesiology , vol.101 , Issue.2 , pp. 527-530
    • Anand, K.J.S.1    Soriano, S.G.2
  • 7
    • 3342941605 scopus 로고    scopus 로고
    • Anesthesia-induced developmental neuroapoptosis: Does it happen in humans?
    • DOI 10.1097/00000542-200408000-00004
    • Olney JW, Young C, Wozniak DF, et al,. Anesthesia-induced developmental neuroapoptosis. Does it happen in humans? Anesthesiology 2004; 101: 273-275. (Pubitemid 38988479)
    • (2004) Anesthesiology , vol.101 , Issue.2 , pp. 273-275
    • Olney, J.W.1    Young, C.2    Wozniak, D.F.3    Ikonomidou, C.4    Jevtovic-Todorovic, V.5
  • 8
    • 44649178281 scopus 로고    scopus 로고
    • An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function
    • Loepke AW, Soriano SG,. An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function. Anesth Analg 2008; 106: 1681-1707.
    • (2008) Anesth Analg , vol.106 , pp. 1681-1707
    • Loepke, A.W.1    Soriano, S.G.2
  • 9
    • 79954552583 scopus 로고    scopus 로고
    • Defining safe use of anesthesia in children
    • Rappaport B, Mellon RD, Simone A, et al,. Defining safe use of anesthesia in children. N Engl J Med 2011; 364: 1387-1390.
    • (2011) N Engl J Med , vol.364 , pp. 1387-1390
    • Rappaport, B.1    Mellon, R.D.2    Simone, A.3
  • 11
    • 84961036080 scopus 로고
    • Evidence that the hypothalamus is responsible for androgen-induced sterility in the female rat
    • Barraclough CA, Gorski RA,. Evidence that the hypothalamus is responsible for androgen-induced sterility in the female rat. Endocrinology 1961; 68: 68-79.
    • (1961) Endocrinology , vol.68 , pp. 68-79
    • Barraclough, C.A.1    Gorski, R.A.2
  • 12
    • 27744484009 scopus 로고
    • The evolution of behavior
    • Lorenz KZ,. The evolution of behavior. Sci Am 1958; 199: 67-74.
    • (1958) Sci Am , vol.199 , pp. 67-74
    • Lorenz, K.Z.1
  • 13
    • 3943087045 scopus 로고    scopus 로고
    • Critical period regulation
    • DOI 10.1146/annurev.neuro.27.070203.144327
    • Hensch TK,. Critical period regulation. Annu Rev Neurosci 2004; 27: 549-579. (Pubitemid 39050413)
    • (2004) Annual Review of Neuroscience , vol.27 , pp. 549-579
    • Hensch, T.K.1
  • 15
    • 0030883534 scopus 로고    scopus 로고
    • Regional differences in synaptogenesis in human cerebral cortex
    • DOI 10.1002/(SICI)1096-9861(19971020)387:2<167::AID-CNE1>3.0.CO;2-Z
    • Huttenlocher PR, Dabholkar AS,. Regional differences in synaptogenesis in human cerebral cortex. J Comp Neurol 1997; 387: 167-178. (Pubitemid 27430343)
    • (1997) Journal of Comparative Neurology , vol.387 , Issue.2 , pp. 167-178
    • Huttenlocher, P.R.1    Dabholkar, A.S.2
  • 16
    • 80051995858 scopus 로고    scopus 로고
    • Extraordinary neoteny of synaptic spines in the human prefrontal cortex
    • Petanjek Z, Judas M, Simic G, et al,. Extraordinary neoteny of synaptic spines in the human prefrontal cortex. Proc Natl Acad Sci U S A 2011; 108: 13281-13286.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13281-13286
    • Petanjek, Z.1    Judas, M.2    Simic, G.3
  • 17
    • 0028114577 scopus 로고
    • Synaptic development of the cerebral cortex: Implications for learning, memory, and mental illness
    • Rakic P, Bourgeois JP, Goldman-Rakic PS,. Synaptic development of the cerebral cortex: implications for learning, memory, and mental illness. Prog Brain Res 1994; 102: 227-243. (Pubitemid 24342669)
    • (1994) Progress in Brain Research , vol.102 , pp. 227-243
    • Rakic, P.1    Bourgeois, J.-P.2    Goldman-Rakic, P.S.3
  • 18
    • 0020405833 scopus 로고
    • The development of pyramidal neurons after eye opening in the visual cortex of hooded rats: A quantitative study
    • DOI 10.1002/cne.902120210
    • Juraska JM,. The development of pyramidal neurons after eye opening in the visual cortex of hooded rats: a quantitative study. J Comp Neurol 1982; 212: 208-213. (Pubitemid 13198500)
    • (1982) Journal of Comparative Neurology , vol.212 , Issue.2 , pp. 208-213
    • Juraska, J.M.1
  • 19
    • 0030700502 scopus 로고    scopus 로고
    • Inhibitory synaptogenesis in mouse somatosensory cortex
    • DOI 10.1093/cercor/7.7.619
    • De Felipe J, Marco P, Fairen A, et al,. Inhibitory synaptogenesis in mouse somatosensory cortex. Cereb Cortex 1997; 7: 619-634. (Pubitemid 27467974)
    • (1997) Cerebral Cortex , vol.7 , Issue.7 , pp. 619-634
    • De Felipe, J.1    Marco, P.2    Fairen, A.3    Jones, E.G.4
  • 20
    • 4344574333 scopus 로고    scopus 로고
    • Molecular and neuronal substrates for general anaesthetics
    • DOI 10.1038/nrn1496
    • Rudolph U, Antkowiak B,. Molecular and neuronal substrates for general anaesthetics. Nat Rev Neurosci 2004; 5: 709-720. (Pubitemid 39150142)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.9 , pp. 709-720
    • Rudolph, U.1    Antkowiak, B.2
  • 21
    • 0023768752 scopus 로고
    • Blockade of intracortical inhibition in kitten striate cortex: Effects on receptive field properties and associated loss of ocular dominance plasticity
    • Ramoa AS, Paradiso MA, Freeman RD,. Blockade of intracortical inhibition in kitten striate cortex: effects on receptive field properties and associated loss of ocular dominance plasticity. Exp Brain Res 1988; 73: 285-296.
    • (1988) Exp Brain Res , vol.73 , pp. 285-296
    • Ramoa, A.S.1    Paradiso, M.A.2    Freeman, R.D.3
  • 22
    • 0025230307 scopus 로고
    • Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist
    • Bear MF, Kleinschmidt A, Gu QA, et al,. Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist. J Neurosci 1990; 10: 909-925. (Pubitemid 20104788)
    • (1990) Journal of Neuroscience , vol.10 , Issue.3 , pp. 909-925
    • Bear, M.F.1    Kleinschmidt, A.2    Gu, Q.3    Singer, W.4
  • 23
    • 0032553477 scopus 로고    scopus 로고
    • Local GABA circuit control of experience-dependent plasticity in developing visual cortex
    • Hensch TK, Fagiolini M, Mataga N, et al,. Local GABA circuit control of experience-dependent plasticity in developing visual cortex. Science 1998; 282: 1504-1508. (Pubitemid 28538615)
    • (1998) Science , vol.282 , Issue.5393 , pp. 1504-1508
    • Hensch, T.K.1    Fagiolini, M.2    Mataga, N.3    Stryker, M.P.4    Baekkeskov, S.5    Kash, S.F.6
  • 24
    • 80052650281 scopus 로고    scopus 로고
    • Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models
    • Gatto CL, Broadie K,. Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models. Front Synaptic Neurosci 2010; 2: 4.
    • (2010) Front Synaptic Neurosci , vol.2 , pp. 4
    • Gatto, C.L.1    Broadie, K.2
  • 25
    • 80053588031 scopus 로고    scopus 로고
    • Molecular mechanisms underlying activity-dependent GABAergic synapse development and plasticity and its implications for neurodevelopmental disorders
    • Chattopadhyaya B,. Molecular mechanisms underlying activity-dependent GABAergic synapse development and plasticity and its implications for neurodevelopmental disorders. Neural Plast 2011; 2011: 734231.
    • (2011) Neural Plast , vol.2011 , pp. 734231
    • Chattopadhyaya, B.1
  • 26
    • 83455172779 scopus 로고    scopus 로고
    • Anesthetic-related neurotoxicity and the developing brain: Shall we change practice?
    • Vutskits L,. Anesthetic-related neurotoxicity and the developing brain: shall we change practice? Paediatr Drugs 2012; 14: 13-21.
    • (2012) Paediatr Drugs , vol.14 , pp. 13-21
    • Vutskits, L.1
  • 27
    • 65349185029 scopus 로고    scopus 로고
    • Early exposure to anesthesia and learning disabilities in a population-based birth cohort
    • Wilder RT, Flick RP, Sprung J, et al,. Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology 2009; 110: 796-804.
    • (2009) Anesthesiology , vol.110 , pp. 796-804
    • Wilder, R.T.1    Flick, R.P.2    Sprung, J.3
  • 28
    • 84856628070 scopus 로고    scopus 로고
    • Attention-deficit/hyperactivity disorder after early exposure to procedures requiring general anesthesia
    • Sprung J, Flick RP, Katusic SK, et al,. Attention-deficit/hyperactivity disorder after early exposure to procedures requiring general anesthesia. Mayo Clin Proc 2012; 87: 120-129.
    • (2012) Mayo Clin Proc , vol.87 , pp. 120-129
    • Sprung, J.1    Flick, R.P.2    Katusic, S.K.3
  • 29
    • 70349742914 scopus 로고    scopus 로고
    • A retrospective cohort study of the association of anesthesia and hernia repair surgery with behavioral and developmental disorders in young children
    • DiMaggio C, Sun LS, Kakavouli A, et al,. A retrospective cohort study of the association of anesthesia and hernia repair surgery with behavioral and developmental disorders in young children. J Neurosurg Anesthesiol 2009; 21: 286-291.
    • (2009) J Neurosurg Anesthesiol , vol.21 , pp. 286-291
    • Dimaggio, C.1    Sun, L.S.2    Kakavouli, A.3
  • 30
    • 80055099285 scopus 로고    scopus 로고
    • Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a sibling birth cohort
    • DiMaggio C, Sun LS, Li G,. Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a sibling birth cohort. Anesth Analg 2011; 113: 1143-1151.
    • (2011) Anesth Analg , vol.113 , pp. 1143-1151
    • Dimaggio, C.1    Sun, L.S.2    Li, G.3
  • 31
    • 70149102255 scopus 로고    scopus 로고
    • Increasing the duration of isoflurane anesthesia decreases the minimum alveolar anesthetic concentration in 7-day-old but not in 60-day-old rats
    • Stratmann G, Sall JW, Eger EI 2nd, et al,. Increasing the duration of isoflurane anesthesia decreases the minimum alveolar anesthetic concentration in 7-day-old but not in 60-day-old rats. Anesth Analg 2009; 109: 801-806.
    • (2009) Anesth Analg , vol.109 , pp. 801-806
    • Stratmann, G.1    Sall, J.W.2    Eger, E.I.3
  • 32
    • 77955173169 scopus 로고    scopus 로고
    • Xenon pretreatment attenuates anesthetic-induced apoptosis in the developing brain in comparison with nitrous oxide and hypoxia
    • Shu Y, Patel SM, Pac-Soo C, et al,. Xenon pretreatment attenuates anesthetic-induced apoptosis in the developing brain in comparison with nitrous oxide and hypoxia. Anesthesiology 2010; 113: 360-368.
    • (2010) Anesthesiology , vol.113 , pp. 360-368
    • Shu, Y.1    Patel, S.M.2    Pac-Soo, C.3
  • 33
    • 77649106829 scopus 로고    scopus 로고
    • Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis
    • Briner A, De Roo M, Dayer A, et al,. Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis. Anesthesiology 2010; 112: 546-556.
    • (2010) Anesthesiology , vol.112 , pp. 546-556
    • Briner, A.1    De Roo, M.2    Dayer, A.3
  • 34
    • 0033932893 scopus 로고    scopus 로고
    • Pentobarbital inhibits apoptosis in neuronal cells
    • Morimoto Y, Morimoto Y, Nishihira J, et al,. Pentobarbital inhibits apoptosis in neuronal cells. Crit Care Med 2000; 28: 1899-19904.
    • (2000) Crit Care Med , vol.28 , pp. 1899-19904
    • Morimoto, Y.1    Morimoto, Y.2    Nishihira, J.3
  • 35
    • 0014883198 scopus 로고
    • Undernutrition and the developing brain. The relevance of animal models to the human problem
    • Dobbing J,. Undernutrition and the developing brain. The relevance of animal models to the human problem. Am J Dis Child 1970; 120: 411-415.
    • (1970) Am J Dis Child , vol.120 , pp. 411-415
    • Dobbing, J.1
  • 36
    • 0019861553 scopus 로고
    • Vulnerability of developing brain not explained by cell number/cell size hypothesis
    • DOI 10.1016/0378-3782(81)90030-X
    • Dobbing J, Sands J,. Vulnerability of developing brain not explained by cell number/cell size hypothesis. Early Hum Dev 1981; 5: 227-231. (Pubitemid 11044252)
    • (1981) Early Human Development , vol.5 , Issue.3 , pp. 227-231
    • Dobbing, J.1    Sands, J.2
  • 37
    • 0018372689 scopus 로고
    • Comparative aspects of the brain growth spurt
    • Dobbing J, Sands J,. Comparative aspects of the brain growth spurt. Early Hum Dev 1979; 3: 79-83. (Pubitemid 9141710)
    • (1979) Early Human Development , vol.3 , Issue.1 , pp. 79-83
    • Dobbing, J.1    Sands, J.2
  • 38
    • 33646067730 scopus 로고    scopus 로고
    • Ontogeny of the human central nervous system: What is happening when?
    • de Graaf-Peters VB, Hadders-Algra M,. Ontogeny of the human central nervous system: what is happening when? Early Hum Dev 2006; 82: 257-266.
    • (2006) Early Hum Dev , vol.82 , pp. 257-266
    • De Graaf-Peters, V.B.1    Hadders-Algra, M.2
  • 39
    • 34948867658 scopus 로고    scopus 로고
    • Extrapolating brain development from experimental species to humans
    • DOI 10.1016/j.neuro.2007.01.014, PII S0161813X07000332
    • Clancy B, Finlay BL, Darlington RB, et al,. Extrapolating brain development from experimental species to humans. Neurotoxicology 2007; 28: 931-937. (Pubitemid 47519794)
    • (2007) NeuroToxicology , vol.28 , Issue.5 , pp. 931-937
    • Clancy, B.1    Finlay, B.L.2    Darlington, R.B.3    Anand, K.J.S.4
  • 40
    • 0035898287 scopus 로고    scopus 로고
    • Translating developmental time across mammalian species
    • DOI 10.1016/S0306-4522(01)00171-3, PII S0306452201001713
    • Clancy B, Darlington RB, Finlay BL,. Translating developmental time across mammalian species. Neuroscience 2001; 105: 7-17. (Pubitemid 32722089)
    • (2001) Neuroscience , vol.105 , Issue.1 , pp. 7-17
    • Clancy, B.1    Darlington, R.B.2    Finlay, B.L.3
  • 41
    • 0033016341 scopus 로고    scopus 로고
    • Shakespeare in love-with NMDA receptors?
    • Lipton SA, Nakanishi N,. Shakespeare in love-with NMDA receptors? Nat Med 1999; 5: 270-271.
    • (1999) Nat Med , vol.5 , pp. 270-271
    • Lipton, S.A.1    Nakanishi, N.2
  • 42
    • 0036742598 scopus 로고    scopus 로고
    • Vulnerability of the developing brain. Neuronal mechanisms
    • Bhutta AT, Anand KJ,. Vulnerability of the developing brain. Neuronal mechanisms. Clin Perinatol 2002; 29: 357-372.
    • (2002) Clin Perinatol , vol.29 , pp. 357-372
    • Bhutta, A.T.1    Anand, K.J.2
  • 43
    • 34250802718 scopus 로고    scopus 로고
    • Ketamine reduces the cell death following inflammatory pain in newborn rat brain
    • DOI 10.1203/PDR.0b013e3180986d2f, PII 0000645020070900000011
    • Anand KJ, Garg S, Rovnaghi CR, et al,. Ketamine reduces the cell death following inflammatory pain in newborn rat brain. Pediatr Res 2007; 62: 283-290. (Pubitemid 47301476)
    • (2007) Pediatric Research , vol.62 , Issue.3 , pp. 283-290
    • Anand, K.J.S.1    Garg, S.2    Rovnaghi, C.R.3    Narsinghani, U.4    Bhutta, A.T.5    Hall, R.W.6
  • 44
    • 84855811125 scopus 로고    scopus 로고
    • Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain
    • Shu Y, Zhou Z, Wan Y, et al,. Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain. Neurobiol Dis 2012; 45: 743-750.
    • (2012) Neurobiol Dis , vol.45 , pp. 743-750
    • Shu, Y.1    Zhou, Z.2    Wan, Y.3
  • 46
    • 0036932564 scopus 로고    scopus 로고
    • Repeated administration of ketamine may lead to neuronal degeneration in the developing rat brain
    • DOI 10.1046/j.1460-9592.2002.00883.x
    • Hayashi H, Dikkes P, Soriano SG,. Repeated administration of ketamine may lead to neuronal degeneration in the developing rat brain. Paediatr Anaesth 2002; 12: 770-774. (Pubitemid 36051344)
    • (2002) Paediatric Anaesthesia , vol.12 , Issue.9 , pp. 770-774
    • Hayashi, H.1    Dikkes, P.2    Soriano, S.G.3
  • 48
    • 58749107529 scopus 로고    scopus 로고
    • The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory
    • Loepke AW, Istaphanous GK, McAuliffe J Jr, et al,. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory. Anesth Analg 2009; 108: 90-104.
    • (2009) Anesth Analg , vol.108 , pp. 90-104
    • Loepke, A.W.1    Istaphanous, G.K.2    McAuliffe, Jr.J.3
  • 49
    • 0033620844 scopus 로고    scopus 로고
    • Methods in health services research: Interpreting the evidence: Choosing between randomised and non-randomised studies
    • McKee M, Britton A, Black N, et al,. Methods in health services research. Interpreting the evidence: choosing between randomised and non-randomised studies. BMJ 1999; 319: 312-315. (Pubitemid 29353952)
    • (1999) British Medical Journal , vol.319 , Issue.7205 , pp. 312-315
    • McKee, M.1    Britton, A.2    Black, N.3    McPherson, K.4    Sanderson, C.5    Bain, C.6
  • 50
    • 77955798109 scopus 로고    scopus 로고
    • Pro-con debate: Cohort studies vs the randomized clinical trial methodology in pediatric anesthesia
    • Hansen TG, Henneberg SW, Morton NS, et al,. Pro-con debate: cohort studies vs the randomized clinical trial methodology in pediatric anesthesia. Pediatr Anesth 2010; 20: 880-894.
    • (2010) Pediatr Anesth , vol.20 , pp. 880-894
    • Hansen, T.G.1    Henneberg, S.W.2    Morton, N.S.3
  • 51
    • 65349136383 scopus 로고    scopus 로고
    • Behavior and development in children and age at the time of first anesthetic exposure
    • Kalkman CJ, Peelen L, Moons KG, et al,. Behavior and development in children and age at the time of first anesthetic exposure. Anesthesiology 2009; 110: 805-812.
    • (2009) Anesthesiology , vol.110 , pp. 805-812
    • Kalkman, C.J.1    Peelen, L.2    Moons, K.G.3
  • 52
    • 80355148374 scopus 로고    scopus 로고
    • Cognitive and behavioral outcomes after early exposure to anesthesia and surgery
    • Flick RP, Katusic SK, Colligan RC, et al,. Cognitive and behavioral outcomes after early exposure to anesthesia and surgery. Pediatrics 2011; 128: e1053-e1061.
    • (2011) Pediatrics , vol.128
    • Flick, R.P.1    Katusic, S.K.2    Colligan, R.C.3
  • 53
    • 68249160838 scopus 로고    scopus 로고
    • Anesthesia for cesarean delivery and learning disabilities in a population-based birth cohort
    • Sprung J, Flick RP, Wilder RT, et al,. Anesthesia for cesarean delivery and learning disabilities in a population-based birth cohort. Anesthesiology 2009; 111: 302-310.
    • (2009) Anesthesiology , vol.111 , pp. 302-310
    • Sprung, J.1    Flick, R.P.2    Wilder, R.T.3
  • 54
    • 79958117305 scopus 로고    scopus 로고
    • Learning disability in children as an outcome in anesthesia and analgesia research
    • Radcliffe J, Bellinger DC,. Learning disability in children as an outcome in anesthesia and analgesia research. Anesth Analg 2011; 112: 1262-1264.
    • (2011) Anesth Analg , vol.112 , pp. 1262-1264
    • Radcliffe, J.1    Bellinger, D.C.2
  • 55
    • 67249155367 scopus 로고    scopus 로고
    • Anesthesia and cognitive performance in children: No evidence for a causal relationship
    • Bartels M, Althoff RR, Boomsma DI,. Anesthesia and cognitive performance in children: no evidence for a causal relationship. Twin Res Hum Genet 2009; 12: 246-253.
    • (2009) Twin Res Hum Genet , vol.12 , pp. 246-253
    • Bartels, M.1    Althoff, R.R.2    Boomsma, D.I.3
  • 56
    • 79955465251 scopus 로고    scopus 로고
    • Academic performance in adolescence after inguinal hernia repair in infancy: A nationwide cohort study
    • Hansen TG, Pedersen JK, Henneberg SW, et al,. Academic performance in adolescence after inguinal hernia repair in infancy: a nationwide cohort study. Anesthesiology 2011; 114: 1076-1085.
    • (2011) Anesthesiology , vol.114 , pp. 1076-1085
    • Hansen, T.G.1    Pedersen, J.K.2    Henneberg, S.W.3


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