Using immobilized G-protein coupled receptors to screen bioactive traditional Chinese medicine compounds with multiple targets

Journal of Pharmaceutical and Biomedical Analysis

Volumn 70, Issue , 2012, Pages 549-552

  Zhao, Xinfeng ^a   Li, Qian ^a   Bian, Liujiao ^a   Zheng, Xiaohui ^a   Zheng, Jianbin ^a   Zhang, Youyi ^b   Li, Zijian ^b  

^a NORTHWEST UNIVERSITY   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

Adrenoceptors covalent immobilization; Berberine; Coptis chinensis; Jatrorrhizine; Palmatine; Salvia miltiorrhiza

Indexed keywords

ADRENALIN; ALPHA 1 ADRENERGIC RECEPTOR; BERBERINE; BETA 2 ADRENERGIC RECEPTOR; COPTIS CHINENSIS EXTRACT; JATRORRHIZINE; PALMATINE; PRAZOSIN; SALBUTAMOL; SALVIA MILTIORRHIZA EXTRACT; SILICA GEL; TERAZOSIN; TERBUTALINE;

ARTICLE; CHINESE MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PRIORITY JOURNAL;

ADRENERGIC AGENTS; ANIMALS; AUTOMATION; CALIBRATION; CHROMATOGRAPHY, AFFINITY; COPTIS; DRUGS, CHINESE HERBAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PLANTS, MEDICINAL; POROSITY; PROTEIN BINDING; RABBITS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA-2; REFERENCE STANDARDS; SALVIA MILTIORRHIZA; SILICA GEL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84866237653     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.05.004     Document Type: Article

References (19)

1. Mayr L.M., Bojanic D. Novel trends in high-throughput screening. Curr. Opin. Pharmacol. 2009, 9:580-586.
2. Galloway W.R.J.D., Isidro-Llobet A., Spring D.R. Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules. Nat. Commun. 2010, 1:1-13.
3. Duong-Thi M.D., Meiby E., Bergström M., Fex T., Isaksson R., Ohlson S. Weak affinity chromatography as a new approach for fragment screening in drug discovery. Anal. Biochem. 2011, 414:138-146.
4. 2-adrenoceptor. Biochem. Pharmacol. 2010, 79:1610-1615.
5. 2-adrenergic receptor agonists. Bioorg. Med. Chem. 2010, 18:728-736.
6. Gandhari M.K., Frazier C.R., Hartenstein J.S., Clox J.F., Bernier M., Wainer I.W. Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells. Mol. Cell. Endocrinol. 2010, 315:314-326.
7. Moaddel R., Rosenberg A., Spelman K., Frazier J., Frazier C., Nocerino S., Brizzi A., Mugnaini C., Wainer I.W. Development and characterization of immobilized cannabinoid receptor (CB1/CB2) open tubular column for on-line screening. Anal. Biochem. 2011, 412:85-91.
8. Yasuda M., Wilson D.R., Fugmann S.D., Moaddel R. Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts. Anal. Chem. 2011, 83:7400-7407.
9. Yan J. Review on pharmacological action of Salvia miltiorrhiza and its bioactive compounds. Chin. Arch. Trad. Chin. Med. 2004, 22:1725-1726.
10. 1-adrenoceptor antagonists on human hyperplastic prostate. Eur. J. Pharmacol. 1999, 374:503-510.
11. 2-adrenoceptor by high-performance liquid chromatography. J. Chromatogr. B 2009, 877:911-918.
12. 1 adrenoceptor. Anal. Biochem. 2005, 339:198-205.
13. Smith P.K., Krohn R.I., Hermanson G.G., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N.M., Olson B.J., Klenk D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 1985, 150:76-85.
14. Kim H.S., Mallik R., Hage D.S. Chromatographic analysis of carbamazepine binding to human serum albumin. II: comparison of the Schiff base and N-hydorxysuccinimide immobilization methods. J. Chromatogr. B 2006, 837:138-146.
15. Tong Z.H., Joseph K.S., Hage D.S. Detection of heterogeneous drug-protein binding by frontal analysis and high-performance affinity chromatography. J. Chromatogr. A 2011, 1218:8915-8924.
16. Ko W.H., Yao X.Q., Lau C.W., Law W.I., Chen Z.Y., Kwok W., Ho K., Huang Y. Vasorelaxant and antiproliferative effects of berberine. Eur. J. Pharmacol. 2000, 399:187-196.
17. Olmez E., Ilhan M. Evaluation of the alpha-adrenoceptor antagonistic action of berberine in isolated organs. Arzneimlttelforschung 1992, 42:1095-1097.
18. Hong Y., Hui S.C., Chan T.Y., Hou J.Y. Effect of berberine on regression of pressure-overload induced cardiac hypertrophy in rats. Am. J. Chin. Med. 2002, 30:1-11.
19. Chang Y.L., Usami S., Hsieh M.T., Jiang M.J. Effects of palmatine on isometric force and intracellular calcium levels of arterial smooth muscle. Life Sci. 1999, 64:597-606.