-
1
-
-
0035204201
-
The nuclear envelope: Filling in gaps
-
PMID:11781582
-
Burke B. The nuclear envelope: filling in gaps. Nat Cell Biol 2001; 3:E273-4; PMID:11781582; http://dx.doi.org/10.1038/ncb1201-e273.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Burke, B.1
-
2
-
-
11244320353
-
The nuclear lamina comes of age
-
PMID:15688064
-
Gruenbaum Y, Margalit A, Goldman RD, Shumaker DK, Wilson KL. The nuclear lamina comes of age. Nat Rev Mol Cell Biol 2005; 6:21-31; PMID:15688064; http://dx.doi.org/10.1038/nrm1550.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 21-31
-
-
Gruenbaum, Y.1
Margalit, A.2
Goldman, R.D.3
Shumaker, D.K.4
Wilson, K.L.5
-
3
-
-
0036347096
-
Life at the edge: The nuclear envelope and human disease
-
PMID:12154369
-
Burke B, Stewart CL. Life at the edge: the nuclear envelope and human disease. Nat Rev Mol Cell Biol 2002; 3:575-85; PMID:12154369; http://dx.doi. org/10.1038/nrm879.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 575-585
-
-
Burke, B.1
Stewart, C.L.2
-
4
-
-
0034799798
-
The nuclear envelope in muscular dystrophy and cardiovascular diseases
-
PMID:11576443
-
Burke B, Mounkes LC, Stewart CL. The nuclear envelope in muscular dystrophy and cardiovascular diseases. Traffic 2001; 2:675-83; PMID:11576443; http://dx.doi.org/10.1034/j.1600-0854.2001.21001.x.
-
(2001)
Traffic
, vol.2
, pp. 675-683
-
-
Burke, B.1
Mounkes, L.C.2
Stewart, C.L.3
-
5
-
-
85047692354
-
How do mutations in lamins A and C cause disease?
-
PMID:14755330
-
Worman HJ, Courvalin JC. How do mutations in lamins A and C cause disease? J Clin Invest 2004; 113:349-51; PMID:14755330.
-
(2004)
J Clin Invest
, vol.113
, pp. 349-351
-
-
Worman, H.J.1
Courvalin, J.C.2
-
6
-
-
0018840796
-
The nuclear envelope lamina is reversibly depolymerized during mitosis
-
PMID:7357605
-
Gerace L, Blobel G. The nuclear envelope lamina is reversibly depolymerized during mitosis. Cell 1980; 19:277-87; PMID:7357605; http://dx.doi. org/10.1016/0092-8674(80)90409-2.
-
(1980)
Cell
, vol.19
, pp. 277-287
-
-
Gerace, L.1
Blobel, G.2
-
7
-
-
77954950116
-
Progeria syndromes and ageing: What is the connection?
-
PMID:20651707
-
Burtner CR, Kennedy BK. Progeria syndromes and ageing: what is the connection? Nat Rev Mol Cell Biol 2010; 11:567-78; PMID:20651707; http://dx.doi.org/10.1038/nrm2944.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 567-578
-
-
Burtner, C.R.1
Kennedy, B.K.2
-
8
-
-
77449109551
-
Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes
-
PMID:19933576
-
Haque F, Mazzeo D, Patel JT, Smallwood DT, Ellis JA, Shanahan CM, et al. Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes. J Biol Chem 2010; 285:3487-98; PMID:19933576; http://dx.doi.org/10.1074/jbc.M109.071910.
-
(2010)
J Biol Chem
, vol.285
, pp. 3487-3498
-
-
Haque, F.1
Mazzeo, D.2
Patel, J.T.3
Smallwood, D.T.4
Ellis, J.A.5
Shanahan, C.M.6
-
9
-
-
70449348833
-
The nuclear envelopathies and human diseases
-
PMID:19849840
-
Chi YH, Chen ZJ, Jeang KT. The nuclear envelopathies and human diseases. J Biomed Sci 2009; 16:96; PMID:19849840; http://dx.doi.org/10.1186/1423-0127-16-96.
-
(2009)
J Biomed Sci
, vol.16
, pp. 96
-
-
Chi, Y.H.1
Chen, Z.J.2
Jeang, K.T.3
-
10
-
-
0032772929
-
UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development
-
PMID:10375507
-
Malone CJ, Fixsen WD, Horvitz HR, Han M. UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development. Development 1999; 126:3171-81; PMID:10375507.
-
(1999)
Development
, vol.126
, pp. 3171-3181
-
-
Malone, C.J.1
Fixsen, W.D.2
Horvitz, H.R.3
Han, M.4
-
11
-
-
34249313304
-
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice
-
PMID:17543860
-
Ding X, Xu R, Yu J, Xu T, Zhuang Y, Han M. SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell 2007; 12:863-72; PMID:17543860; http://dx.doi. org/10.1016/j.devcel.2007.03.018.
-
(2007)
Dev Cell
, vol.12
, pp. 863-872
-
-
Ding, X.1
Xu, R.2
Yu, J.3
Xu, T.4
Zhuang, Y.5
Han, M.6
-
12
-
-
66149104767
-
Requirement for Sun1 in the expression of meiotic reproductive genes and piRNA
-
PMID:19211677
-
Chi YH, Cheng LI, Myers T, Ward JM, Williams E, Su Q, et al. Requirement for Sun1 in the expression of meiotic reproductive genes and piRNA. Development 2009; 136:965-73; PMID:19211677; http://dx.doi.org/10.1242/dev.029868.
-
(2009)
Development
, vol.136
, pp. 965-973
-
-
Chi, Y.H.1
Cheng, L.I.2
Myers, T.3
Ward, J.M.4
Williams, E.5
Su, Q.6
-
13
-
-
33646555082
-
SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton
-
PMID:16648470
-
Haque F, Lloyd DJ, Smallwood DT, Dent CL, Shanahan CM, Fry AM, et al. SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton. Mol Cell Biol 2006; 26:3738-51; PMID:16648470; http://dx.doi.org/10.1128/MCB.26.10.3738-3751.2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3738-3751
-
-
Haque, F.1
Lloyd, D.J.2
Smallwood, D.T.3
Dent, C.L.4
Shanahan, C.M.5
Fry, A.M.6
-
14
-
-
69449090753
-
Bringing KASH under the SUN: The many faces of nucleo-cytoskeletal connections
-
PMID: 19687252
-
Razafsky D, Hodzic D. Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections. J Cell Biol 2009;186:461-72; PMID: 19687252; http://dx.doi.org/10.1083/jcb.200906068.
-
(2009)
J Cell Biol
, vol.186
, pp. 461-472
-
-
Razafsky, D.1
Hodzic, D.2
-
15
-
-
24344502371
-
The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope
-
PMID:16079285
-
Padmakumar VC, Libotte T, Lu W, Zaim H, Abraham S, Noegel AA, et al. The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope. J Cell Sci 2005; 118:3419-30; PMID:16079285; http://dx.doi. org/10.1242/jcs.02471.
-
(2005)
J Cell Sci
, vol.118
, pp. 3419-3430
-
-
Padmakumar, V.C.1
Libotte, T.2
Lu, W.3
Zaim, H.4
Abraham, S.5
Noegel, A.A.6
-
16
-
-
84860327128
-
Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies
-
PMID:22541428
-
Chen CY, Chi YH, Mutalif RA, Starost MF, Myers TG, Anderson SA, et al. Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies. Cell 2012; 149:565-77; PMID:22541428; http://dx.doi. org/10.1016/j.cell.2012.01.059.
-
(2012)
Cell
, vol.149
, pp. 565-577
-
-
Chen, C.Y.1
Chi, Y.H.2
Mutalif, R.A.3
Starost, M.F.4
Myers, T.G.5
Anderson, S.A.6
-
17
-
-
25644440744
-
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
-
PMID:16079796
-
Varela I, Cadiñanos J, Pendás AM, Gutiérrez-Fernández A, Folgueras AR, Sánchez LM, et al. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature 2005; 437:564-8; PMID:16079796; http://dx.doi. org/10.1038/nature04019.
-
(2005)
Nature
, vol.437
, pp. 564-568
-
-
Varela, I.1
Cadiñanos, J.2
Pendás, A.M.3
Gutiérrez-Fernández, A.4
Folgueras, A.R.5
Sánchez, L.M.6
-
18
-
-
59449095581
-
Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53
-
PMID:18843043
-
Kudlow BA, Stanfel MN, Burtner CR, Johnston ED, Kennedy BK. Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53. Mol Biol Cell 2008; 19:5238-48; PMID:18843043; http://dx.doi. org/10.1091/mbc.E08-05-0492.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5238-5248
-
-
Kudlow, B.A.1
Stanfel, M.N.2
Burtner, C.R.3
Johnston, E.D.4
Kennedy, B.K.5
-
19
-
-
0037673940
-
A progeroid syndrome in mice is caused by defects in A-type lamins
-
PMID:12748643
-
Mounkes LC, Kozlov S, Hernandez L, Sullivan T, Stewart CL. A progeroid syndrome in mice is caused by defects in A-type lamins. Nature 2003; 423:298-301; PMID:12748643; http://dx.doi.org/10.1038/nature01631.
-
(2003)
Nature
, vol.423
, pp. 298-301
-
-
Mounkes, L.C.1
Kozlov, S.2
Hernandez, L.3
Sullivan, T.4
Stewart, C.L.5
-
20
-
-
0033615969
-
Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy
-
PMID:10579712
-
Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 1999; 147:913-20; PMID:10579712; http://dx.doi. org/10.1083/jcb.147.5.913.
-
(1999)
J Cell Biol
, vol.147
, pp. 913-920
-
-
Sullivan, T.1
Escalante-Alcalde, D.2
Bhatt, H.3
Anver, M.4
Bhat, N.5
Nagashima, K.6
-
21
-
-
84865140739
-
From loss to gain: Role for SUN1 in laminopathies
-
PMID: 22709970
-
Liu B, Jin DY, Zhou Z. From loss to gain: role for SUN1 in laminopathies. Cell Biosci 2012; 2:21; PMID: 22709970; http://dx.doi.org/10.1186/2045-3701-2-21.
-
(2012)
Cell Biosci
, vol.2
, pp. 21
-
-
Liu, B.1
Jin, D.Y.2
Zhou, Z.3
-
22
-
-
79961100778
-
Lysosomal storage disorders: Molecular basis and laboratory testing
-
PMID:21504867
-
Filocamo M, Morrone A. Lysosomal storage disorders: molecular basis and laboratory testing. Hum Genomics 2011; 5:156-69; PMID:21504867; http://dx.doi.org/10.1186/1479-7364-5-3-156.
-
(2011)
Hum Genomics
, vol.5
, pp. 156-169
-
-
Filocamo, M.1
Morrone, A.2
-
23
-
-
46549084254
-
Protein misfolding and disease: From the test tube to the organism
-
PMID:18295611
-
Luheshi LM, Crowther DC, Dobson CM. Protein misfolding and disease: from the test tube to the organism. Curr Opin Chem Biol 2008; 12:25-31; PMID:18295611; http://dx.doi.org/10.1016/j. cbpa.2008.02.011.
-
(2008)
Curr Opin Chem Biol
, vol.12
, pp. 25-31
-
-
Luheshi, L.M.1
Crowther, D.C.2
Dobson, C.M.3
-
24
-
-
0037018773
-
Endoplasmic reticulum storage diseases
-
PMID:12087487
-
Rutishauser J, Spiess M. Endoplasmic reticulum storage diseases. Swiss Med Wkly 2002; 132:211-22; PMID:12087487.
-
(2002)
Swiss Med Wkly
, vol.132
, pp. 211-222
-
-
Rutishauser, J.1
Spiess, M.2
-
25
-
-
77953892400
-
Molecular mechanisms of neurodegeneration in Alzheimer's disease
-
PMID:20413653
-
Crews L, Masliah E. Molecular mechanisms of neurodegeneration in Alzheimer's disease. Hum Mol Genet 2010; 19(R1):R12-20; PMID:20413653; http://dx.doi.org/10.1093/hmg/ddq160.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.R1
-
-
Crews, L.1
Masliah, E.2
-
26
-
-
57049117856
-
Cell death and endoplasmic reticulum stress: Disease relevance and therapeutic opportunities
-
PMID:19043451
-
Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2008; 7:1013-30; PMID:19043451; http://dx.doi.org/10.1038/nrd2755.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 1013-1030
-
-
Kim, I.1
Xu, W.2
Reed, J.C.3
-
27
-
-
38949105879
-
Phenotype and course of Hutchinson-Gilford progeria syndrome
-
PMID:18256394
-
Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB, et al. Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med 2008; 358:592-604; PMID:18256394; http://dx.doi.org/10.1056/NEJMoa0706898.
-
(2008)
N Engl J Med
, vol.358
, pp. 592-604
-
-
Merideth, M.A.1
Gordon, L.B.2
Clauss, S.3
Sachdev, V.4
Smith, A.C.5
Perry, M.B.6
-
28
-
-
77954886484
-
A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane
-
PMID:20551905
-
Turgay Y, Ungricht R, Rothballer A, Kiss A, Csucs G, Horvath P, et al. A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane. EMBO J 2010; 29:2262-75; PMID:20551905; http://dx.doi.org/10.1038/emboj.2010.119.
-
(2010)
EMBO J
, vol.29
, pp. 2262-2275
-
-
Turgay, Y.1
Ungricht, R.2
Rothballer, A.3
Kiss, A.4
Csucs, G.5
Horvath, P.6
-
29
-
-
84863883702
-
Entry and exit mechanisms at the cis-face of the Golgi complex
-
PMID:21482742
-
Lorente-Rodríguez A, Barlowe C. Entry and exit mechanisms at the cis-face of the Golgi complex. Cold Spring Harb Perspect Biol 2011; 3:a005207; PMID:21482742; http://dx.doi.org/10.1101/cshperspect. a005207.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Lorente-Rodríguez, A.1
Barlowe, C.2
-
30
-
-
34548320825
-
Functional association of Sun1 with nuclear pore complexes
-
PMID:17724119
-
Liu Q, Pante N, Misteli T, Elsagga M, Crisp M, Hodzic D, et al. Functional association of Sun1 with nuclear pore complexes. J Cell Biol 2007; 178:785-98; PMID:17724119; http://dx.doi.org/10.1083/jcb.200704108.
-
(2007)
J Cell Biol
, vol.178
, pp. 785-798
-
-
Liu, Q.1
Pante, N.2
Misteli, T.3
Elsagga, M.4
Crisp, M.5
Hodzic, D.6
-
31
-
-
0034902488
-
Both emerin and lamin C depend on lamin A for localization at the nuclear envelope
-
Whitfield WGF, PMID:11683386
-
Vaughan A, Alvarez-Reyes M, Bridger JM, Broers JL, Ramaekers FC, Wehnert M, et al.; Whitfield WGF. Both emerin and lamin C depend on lamin A for localization at the nuclear envelope. J Cell Sci 2001; 114:2577-90; PMID:11683386.
-
(2001)
J Cell Sci
, vol.114
, pp. 2577-2590
-
-
Vaughan, A.1
Alvarez-Reyes, M.2
Bridger, J.M.3
Broers, J.L.4
Ramaekers, F.C.5
Wehnert, M.6
-
32
-
-
17644373758
-
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
-
PMID:15750600
-
Scaffidi P, Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med 2005; 11:440-5; PMID:15750600; http://dx.doi.org/10.1038/nm1204.
-
(2005)
Nat Med
, vol.11
, pp. 440-445
-
-
Scaffidi, P.1
Misteli, T.2
-
33
-
-
18744375181
-
Concepts in nuclear architecture
-
PMID:15832379
-
Misteli T. Concepts in nuclear architecture. Bioessays 2005; 27:477-87; PMID:15832379; http://dx.doi. org/10.1002/bies.20226.
-
(2005)
Bioessays
, vol.27
, pp. 477-487
-
-
Misteli, T.1
-
34
-
-
26444463068
-
Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome
-
PMID:16186497
-
Mallampalli MP, Huyer G, Bendale P, Gelb MH, Michaelis S. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A 2005; 102:14416-21; PMID:16186497; http://dx.doi.org/10.1073/pnas.0503712102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14416-14421
-
-
Mallampalli, M.P.1
Huyer, G.2
Bendale, P.3
Gelb, M.H.4
Michaelis, S.5
-
35
-
-
79953185053
-
Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect
-
PMID:21383178
-
Verstraeten VL, Peckham LA, Olive M, Capell BC, Collins FS, Nabel EG, et al. Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect. Proc Natl Acad Sci U S A 2011; 108:4997-5002; PMID:21383178; http://dx.doi.org/10.1073/pnas.1019532108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 4997-5002
-
-
Verstraeten, V.L.1
Peckham, L.A.2
Olive, M.3
Capell, B.C.4
Collins, F.S.5
Nabel, E.G.6
-
36
-
-
79959776029
-
Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
-
PMID:21715679
-
Cao K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, et al. Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci Transl Med 2011; 3:89ra58; PMID:21715679; http://dx.doi.org/10.1126/scitranslmed.3002346.
-
(2011)
Sci Transl Med
, vol.3
-
-
Cao, K.1
Graziotto, J.J.2
Blair, C.D.3
Mazzulli, J.R.4
Erdos, M.R.5
Krainc, D.6
-
37
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
PMID:19587680
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460:392-5; PMID:19587680.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
|