Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression

Food and Chemical Toxicology

Volumn 50, Issue 11, 2012, Pages 3996-4002

  Jeong, Yun Jeong ^a,b   Cho, Hyun Ji ^a   Whang, Key ^b   Lee, In Seon ^b   Park, Kwan Kyu ^a   Choe, Jung Yoon ^a   Han, Sang Mi ^c   Kim, Cheorl Ho ^d   Chang, Hyeun Wook ^e   Moon, Sung Kwon ^f   Kim, Wun Jae ^g   Choi, Yung Hyun ^h   Chang, Young Chae ^a  

^a Catholic University of Daegu   (South Korea)

^b Keimyung University   (South Korea)

^c National Institute of Animal Science   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e Yeungnam University   (South Korea)

^f Chungju National University   (South Korea)

^g Chungbuk National University   (South Korea)

^h Dong Eui University   (South Korea)

Author keywords

Atherosclerosis; Bee venom; Melittin; VSMC

Indexed keywords

GELATINASE A; GELATINASE B; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIGEL; MELITTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

AORTA; ARTICLE; CELL ASSAY; CELL MIGRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MATRIX METALLOPROTEINASE 9 GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

AORTA; CELL MOVEMENT; CELLS, CULTURED; HUMANS; I-KAPPA B PROTEINS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; MELITTEN; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; TUMOR NECROSIS FACTOR-ALPHA;

APOIDEA;

EID: 84866180605     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.08.026     Document Type: Article

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