Cytokine combination therapy prediction for bone remodeling in tissue engineering based on the intracellular signaling pathway

Biomaterials

Volumn 33, Issue 33, 2012, Pages 8265-8276

  Sun, Xiaoqiang ^a,b   Su, Jing ^a   Bao, Jiguang ^b   Peng, Tao ^a   Zhang, Le ^e,f   Zhang, Yuanyuan ^c   Yang, Yunzhi ^d   Zhou, Xiaobo ^a  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b BEIJING NORMAL UNIVERSITY   (China)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d STANFORD UNIVERSITY   (United States)

^e MICHIGAN TECHNOLOGICAL UNIVERSITY   (United States)

^f SOUTHWEST UNIVERSITY   (China)

Author keywords

Bone remodeling; Bone tissue engineering; Cytokine combination therapy; Osteogenic differentiation; Signaling pathway; Systems biology

Indexed keywords

BONE REMODELING; BONE TISSUE ENGINEERING; COMBINATION THERAPY; OSTEOGENIC DIFFERENTIATION; SIGNALING PATHWAYS; SYSTEMS BIOLOGY;

DISEASES; HYDROGELS; ORDINARY DIFFERENTIAL EQUATIONS; PIGMENTS; SIGNALING; TISSUE; TISSUE ENGINEERING; TRANSCRIPTION FACTORS;

BONE;

BONE MORPHOGENETIC PROTEIN 2; CYTOKINE; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ARTICLE; BONE DENSITY; BONE MASS; BONE REGENERATION; BONE REMODELING; CELL COMMUNICATION; CELL LINEAGE; CELL POPULATION; CYTOKINE RELEASE; HYDROGEL; MOLECULAR DYNAMICS; OSTEOBLAST; OSTEOLYSIS; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; TISSUE ENGINEERING;

BONE MORPHOGENETIC PROTEIN 2; BONE REMODELING; CELL DIFFERENTIATION; CYTOKINES; HUMANS; OSTEOBLASTS; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; TISSUE ENGINEERING; WNT PROTEINS;

EID: 84866174424     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.07.041     Document Type: Article

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