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Volumn 18, Issue 10, 2012, Pages 1540-1551

Selective Purging of Human Multiple Myeloma Cells from Autologous Stem Cell Transplantation Grafts using Oncolytic Myxoma Virus

Author keywords

Autologous hematopoietic stem cell transplantation; Ex vivo purging; Multiple myeloma; Myxoma virus; Viral oncolytics

Indexed keywords

ONCOLYTIC VIRUS; SYNDECAN 1;

EID: 84866156501     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2012.04.004     Document Type: Article
Times cited : (52)

References (46)
  • 1
    • 77951923656 scopus 로고    scopus 로고
    • Survival and years of life lost in different age cohorts of patients with multiple myeloma
    • Ludwig H., Bolejack V., Crowley J., et al. Survival and years of life lost in different age cohorts of patients with multiple myeloma. J Clin Oncol 2010, 28:1599-1605.
    • (2010) J Clin Oncol , vol.28 , pp. 1599-1605
    • Ludwig, H.1    Bolejack, V.2    Crowley, J.3
  • 2
    • 41949114641 scopus 로고    scopus 로고
    • Recent major improvement in long-term survival of younger patients with multiple myeloma
    • Brenner H., Gondos A., Pulte D. Recent major improvement in long-term survival of younger patients with multiple myeloma. Blood 2008, 111:2521-2526.
    • (2008) Blood , vol.111 , pp. 2521-2526
    • Brenner, H.1    Gondos, A.2    Pulte, D.3
  • 3
    • 41949130070 scopus 로고    scopus 로고
    • Improved survival in multiple myeloma and the impact of novel therapies
    • Kumar S.K., Rajkumar S.V., Dispenzieri A., et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2008, 111:2516-2520.
    • (2008) Blood , vol.111 , pp. 2516-2520
    • Kumar, S.K.1    Rajkumar, S.V.2    Dispenzieri, A.3
  • 4
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Français du Myélome
    • Attal M., Harousseau J.L., Stoppa A.M., et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Français du Myélome. N Engl J Med 1996, 335:91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 5
    • 35348991080 scopus 로고    scopus 로고
    • High-dose treatment with autologous stem cell transplantation in multiple myeloma: past, present, and future
    • Björkstrand B., Gahrton G. High-dose treatment with autologous stem cell transplantation in multiple myeloma: past, present, and future. Semin Hematol 2007, 44:227-233.
    • (2007) Semin Hematol , vol.44 , pp. 227-233
    • Björkstrand, B.1    Gahrton, G.2
  • 6
    • 0031050038 scopus 로고    scopus 로고
    • Monoclonal plasma cells in the blood stem cell harvest from patients with multiple myeloma are associated with shortened relapse-free survival after transplantation
    • Gertz M.A., Witzig T.E., Pineda A.A., Greipp P.R., Kyle R.A., Litzow M.R. Monoclonal plasma cells in the blood stem cell harvest from patients with multiple myeloma are associated with shortened relapse-free survival after transplantation. Bone Marrow Transplant 1997, 19:337-342.
    • (1997) Bone Marrow Transplant , vol.19 , pp. 337-342
    • Gertz, M.A.1    Witzig, T.E.2    Pineda, A.A.3    Greipp, P.R.4    Kyle, R.A.5    Litzow, M.R.6
  • 7
    • 0033876925 scopus 로고    scopus 로고
    • The detection of contaminating clonal cells in apheresis products is related to response and outcome in multiple myeloma undergoing autologous peripheral blood stem cell transplantation
    • López-Pérez R., García-Sanz R., González D., et al. The detection of contaminating clonal cells in apheresis products is related to response and outcome in multiple myeloma undergoing autologous peripheral blood stem cell transplantation. Leukemia 2000, 14:1493-1499.
    • (2000) Leukemia , vol.14 , pp. 1493-1499
    • López-Pérez, R.1    García-Sanz, R.2    González, D.3
  • 8
    • 13744259293 scopus 로고    scopus 로고
    • Myeloma cell contamination of peripheral blood stem-cell grafts can predict the outcome in multiple myeloma patients after high-dose chemotherapy and autologous stem-cell transplantation
    • Vogel W., Kopp H.G., Kanz L., Einsele H. Myeloma cell contamination of peripheral blood stem-cell grafts can predict the outcome in multiple myeloma patients after high-dose chemotherapy and autologous stem-cell transplantation. J Cancer Res Clin Oncol 2005, 131:214-218.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 214-218
    • Vogel, W.1    Kopp, H.G.2    Kanz, L.3    Einsele, H.4
  • 9
    • 51649085791 scopus 로고    scopus 로고
    • Comparison of twin and autologous transplants for multiple myeloma
    • Bashey A., Pérez W.S., Zhang M.J., et al. Comparison of twin and autologous transplants for multiple myeloma. Biol Blood Marrow Transplant 2008, 14:1118-1124.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 1118-1124
    • Bashey, A.1    Pérez, W.S.2    Zhang, M.J.3
  • 10
    • 0032862958 scopus 로고    scopus 로고
    • Syngeneic transplantation in multiple myeloma - a case-matched comparison with autologous and allogeneic transplantation. European Group for Blood and Marrow Transplantation
    • Gahrton G., Svensson H., Björkstrand B., et al. Syngeneic transplantation in multiple myeloma - a case-matched comparison with autologous and allogeneic transplantation. European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 1999, 24:741-745.
    • (1999) Bone Marrow Transplant , vol.24 , pp. 741-745
    • Gahrton, G.1    Svensson, H.2    Björkstrand, B.3
  • 11
    • 0029834790 scopus 로고    scopus 로고
    • Syngeneic marrow transplantation in patients with multiple myeloma
    • Bensinger W.I., Demirer T., Buckner C.D., et al. Syngeneic marrow transplantation in patients with multiple myeloma. Bone Marrow Transplant 1996, 18:527-531.
    • (1996) Bone Marrow Transplant , vol.18 , pp. 527-531
    • Bensinger, W.I.1    Demirer, T.2    Buckner, C.D.3
  • 12
    • 4544255016 scopus 로고    scopus 로고
    • Graft purging in autologous bone marrow transplantation: a promise not quite fulfilled
    • discussion 876-878, 881, 884
    • Alvarnas J.C., Forman S.J. Graft purging in autologous bone marrow transplantation: a promise not quite fulfilled. Oncology (Williston Park) 2004, 18:867-876. discussion 876-878, 881, 884.
    • (2004) Oncology (Williston Park) , vol.18 , pp. 867-876
    • Alvarnas, J.C.1    Forman, S.J.2
  • 13
    • 0030698255 scopus 로고    scopus 로고
    • Pharmacological purging of minimal residual disease from peripheral blood stem cell collections of acute myeloblastic leukemia patients: preclinical studies
    • Motta M.R., Mangianti S., Rizzi S., et al. Pharmacological purging of minimal residual disease from peripheral blood stem cell collections of acute myeloblastic leukemia patients: preclinical studies. Exp Hematol 1997, 25:1261-1269.
    • (1997) Exp Hematol , vol.25 , pp. 1261-1269
    • Motta, M.R.1    Mangianti, S.2    Rizzi, S.3
  • 14
    • 38049170585 scopus 로고    scopus 로고
    • 4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG
    • Strauss G., Westhoff M.A., Fischer-Posovszky P., et al. 4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG. Cell Death Differ 2008, 15:332-343.
    • (2008) Cell Death Differ , vol.15 , pp. 332-343
    • Strauss, G.1    Westhoff, M.A.2    Fischer-Posovszky, P.3
  • 15
    • 0032031512 scopus 로고    scopus 로고
    • Purging of mammary carcinoma cells during ex vivo culture of CD34+ hematopoietic progenitor cells with recombinant immunotoxins
    • Spyridonidis A., Schmidt M., Bernhardt W., et al. Purging of mammary carcinoma cells during ex vivo culture of CD34+ hematopoietic progenitor cells with recombinant immunotoxins. Blood 1998, 91:1820-1827.
    • (1998) Blood , vol.91 , pp. 1820-1827
    • Spyridonidis, A.1    Schmidt, M.2    Bernhardt, W.3
  • 16
    • 0026620975 scopus 로고
    • Large-scale immunomagnetic separation system for the removal of tumor cells from bone marrow
    • Gee A., Moss T., Mansour V., et al. Large-scale immunomagnetic separation system for the removal of tumor cells from bone marrow. Prog Clin Biol Res 1992, 377:181-187.
    • (1992) Prog Clin Biol Res , vol.377 , pp. 181-187
    • Gee, A.1    Moss, T.2    Mansour, V.3
  • 17
    • 79960385474 scopus 로고    scopus 로고
    • Ex vivo graft purging and expansion of autologous blood progenitor cell products from patients with multiple myeloma
    • Yang H., Robinson S.N., Nieto Y., et al. Ex vivo graft purging and expansion of autologous blood progenitor cell products from patients with multiple myeloma. Cancer Res 2011, 71:5040-5049.
    • (2011) Cancer Res , vol.71 , pp. 5040-5049
    • Yang, H.1    Robinson, S.N.2    Nieto, Y.3
  • 18
    • 60349110006 scopus 로고    scopus 로고
    • Contaminating tumour cells in autologous PBSC grafts do not influence survival or relapse following transplant for multiple myeloma or B-cell non-Hodgkin's lymphoma
    • Ho J., Yang L., Banihashemi B., et al. Contaminating tumour cells in autologous PBSC grafts do not influence survival or relapse following transplant for multiple myeloma or B-cell non-Hodgkin's lymphoma. Bone Marrow Transplant 2009, 43:223-228.
    • (2009) Bone Marrow Transplant , vol.43 , pp. 223-228
    • Ho, J.1    Yang, L.2    Banihashemi, B.3
  • 19
    • 35748962021 scopus 로고    scopus 로고
    • Relapse risk after autologous transplantation in patients with newly diagnosed myeloma is not related with infused tumor cell load and the outcome is not improved by CD34+ cell selection: long term follow-up of an EBMT phase III randomized study
    • Bourhis J.H., Bouko Y., Koscielny S., et al. Relapse risk after autologous transplantation in patients with newly diagnosed myeloma is not related with infused tumor cell load and the outcome is not improved by CD34+ cell selection: long term follow-up of an EBMT phase III randomized study. Haematologica 2007, 92:1083-1090.
    • (2007) Haematologica , vol.92 , pp. 1083-1090
    • Bourhis, J.H.1    Bouko, Y.2    Koscielny, S.3
  • 20
    • 0031754533 scopus 로고    scopus 로고
    • Autologous transplantation of mobilized peripheral blood CD34+ cells selected by immunomagnetic procedures in patients with multiple myeloma
    • Abonour R., Scott K.M., Kunkel L.A., et al. Autologous transplantation of mobilized peripheral blood CD34+ cells selected by immunomagnetic procedures in patients with multiple myeloma. Bone Marrow Transplant 1998, 22:957-963.
    • (1998) Bone Marrow Transplant , vol.22 , pp. 957-963
    • Abonour, R.1    Scott, K.M.2    Kunkel, L.A.3
  • 21
    • 0035449067 scopus 로고    scopus 로고
    • Purging of autologous peripheral-blood stem cells using CD34 selection does not improve overall or progression-free survival after high-dose chemotherapy for multiple myeloma: results of a multicenter randomized controlled trial
    • Stewart A.K., Vescio R., Schiller G., et al. Purging of autologous peripheral-blood stem cells using CD34 selection does not improve overall or progression-free survival after high-dose chemotherapy for multiple myeloma: results of a multicenter randomized controlled trial. J Clin Oncol 2001, 19:3771-3779.
    • (2001) J Clin Oncol , vol.19 , pp. 3771-3779
    • Stewart, A.K.1    Vescio, R.2    Schiller, G.3
  • 22
    • 0030022520 scopus 로고    scopus 로고
    • Concomitant mobilization of plasma cells and hematopoietic progenitors into peripheral blood of multiple myeloma patients: positive selection and transplantation of enriched CD34+ cells to remove circulating tumor cells
    • Lemoli R.M., Fortuna A., Motta M.R., et al. Concomitant mobilization of plasma cells and hematopoietic progenitors into peripheral blood of multiple myeloma patients: positive selection and transplantation of enriched CD34+ cells to remove circulating tumor cells. Blood 1996, 87:1625-1634.
    • (1996) Blood , vol.87 , pp. 1625-1634
    • Lemoli, R.M.1    Fortuna, A.2    Motta, M.R.3
  • 23
    • 0036143670 scopus 로고    scopus 로고
    • Efficacy and safety of CD34-selected and CD19-depleted autografting in multiple myeloma patients: a pilot study
    • Rasmussen T., Björkstrand B., Andersen H., Gaarsdal E., Johnsen H.E. Efficacy and safety of CD34-selected and CD19-depleted autografting in multiple myeloma patients: a pilot study. Exp Hematol 2002, 30:82-88.
    • (2002) Exp Hematol , vol.30 , pp. 82-88
    • Rasmussen, T.1    Björkstrand, B.2    Andersen, H.3    Gaarsdal, E.4    Johnsen, H.E.5
  • 24
    • 0036113841 scopus 로고    scopus 로고
    • Qualitative and quantitative polymerase chain reaction detection of the residual myeloma cell contamination after positive selection of CD34+ cells with small- and large-scale Miltenyi cell sorting system
    • Voena C., Locatelli G., Castellino C., et al. Qualitative and quantitative polymerase chain reaction detection of the residual myeloma cell contamination after positive selection of CD34+ cells with small- and large-scale Miltenyi cell sorting system. Br J Haematol 2002, 117:642-645.
    • (2002) Br J Haematol , vol.117 , pp. 642-645
    • Voena, C.1    Locatelli, G.2    Castellino, C.3
  • 25
    • 0031036891 scopus 로고    scopus 로고
    • CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements
    • Szczepek A.J., Bergsagel P.L., Axelsson L., Brown C.B., Belch A.R., Pilarski L.M. CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements. Blood 1997, 89:1824-1833.
    • (1997) Blood , vol.89 , pp. 1824-1833
    • Szczepek, A.J.1    Bergsagel, P.L.2    Axelsson, L.3    Brown, C.B.4    Belch, A.R.5    Pilarski, L.M.6
  • 26
    • 0027990411 scopus 로고
    • Cellular origin and extent of clonal involvement in multiple myeloma: genetic and phenotypic studies
    • Takishita M., Kosaka M., Goto T., Saito S. Cellular origin and extent of clonal involvement in multiple myeloma: genetic and phenotypic studies. Br J Haematol 1994, 87:735-742.
    • (1994) Br J Haematol , vol.87 , pp. 735-742
    • Takishita, M.1    Kosaka, M.2    Goto, T.3    Saito, S.4
  • 27
    • 74049127994 scopus 로고    scopus 로고
    • Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic stem and progenitor cells
    • Kim M., Madlambayan G.J., Rahman M.M., et al. Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic stem and progenitor cells. Leukemia 2009, 23:2313-2317.
    • (2009) Leukemia , vol.23 , pp. 2313-2317
    • Kim, M.1    Madlambayan, G.J.2    Rahman, M.M.3
  • 28
  • 29
    • 34748903753 scopus 로고    scopus 로고
    • Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer
    • Stanford M.M., McFadden G. Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer. Expert Opin Biol Ther 2007, 7:1415-1425.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 1415-1425
    • Stanford, M.M.1    McFadden, G.2
  • 30
    • 77953538303 scopus 로고    scopus 로고
    • Oncolytic viral purging of leukemic hematopoietic stem and progenitor cells with Myxoma virus
    • Rahman M.M., Madlambayan G.J., Cogle C.R., McFadden G. Oncolytic viral purging of leukemic hematopoietic stem and progenitor cells with Myxoma virus. Cytokine Growth Factor Rev 2010, 21:169-175.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 169-175
    • Rahman, M.M.1    Madlambayan, G.J.2    Cogle, C.R.3    McFadden, G.4
  • 31
    • 0038709512 scopus 로고    scopus 로고
    • Role of the serine-threonine kinase PAK-1 in myxoma virus replication
    • Johnston J.B., Barrett J.W., Chang W., et al. Role of the serine-threonine kinase PAK-1 in myxoma virus replication. J Virol 2003, 77:5877-5888.
    • (2003) J Virol , vol.77 , pp. 5877-5888
    • Johnston, J.B.1    Barrett, J.W.2    Chang, W.3
  • 32
    • 77952210238 scopus 로고    scopus 로고
    • Myxoma virus: propagation, purification, quantification, and storage
    • Chapter 14:Unit 14A 1
    • Smallwood S.E., Rahman M.M., Smith D.W., McFadden G. Myxoma virus: propagation, purification, quantification, and storage. Curr Protoc Microbiol 2010, Chapter 14:Unit 14A 1.
    • (2010) Curr Protoc Microbiol
    • Smallwood, S.E.1    Rahman, M.M.2    Smith, D.W.3    McFadden, G.4
  • 33
    • 0027170123 scopus 로고
    • SERP1, a serine proteinase inhibitor encoded by myxoma virus, is a secreted glycoprotein that interferes with inflammation
    • Macen J.L., Upton C., Nation N., McFadden G. SERP1, a serine proteinase inhibitor encoded by myxoma virus, is a secreted glycoprotein that interferes with inflammation. Virology 1993, 195:348-363.
    • (1993) Virology , vol.195 , pp. 348-363
    • Macen, J.L.1    Upton, C.2    Nation, N.3    McFadden, G.4
  • 34
    • 84862794917 scopus 로고    scopus 로고
    • Acute myeloid leukemia targeting by myxoma virus in vivo depends on cell binding and not permissiveness to infection in vitro
    • Madlambayan G., Bartee E., Kim M., et al. Acute myeloid leukemia targeting by myxoma virus in vivo depends on cell binding and not permissiveness to infection in vitro. Leuk Res 2012, 36:619-624.
    • (2012) Leuk Res , vol.36 , pp. 619-624
    • Madlambayan, G.1    Bartee, E.2    Kim, M.3
  • 35
    • 0031906150 scopus 로고    scopus 로고
    • A27L protein mediates vaccinia virus interaction with cell surface heparan sulfate
    • Chung C.S., Hsiao J.C., Chang Y.S., Chang W. A27L protein mediates vaccinia virus interaction with cell surface heparan sulfate. J Virol 1998, 72:1577-1585.
    • (1998) J Virol , vol.72 , pp. 1577-1585
    • Chung, C.S.1    Hsiao, J.C.2    Chang, Y.S.3    Chang, W.4
  • 37
    • 84862797578 scopus 로고    scopus 로고
    • Oncolytic virotherapy for hematological malignancies. Adv Virol. 2012;2012:1865512.
    • Bais S, Bartee E, Rahman MM, McFadden G, Cogle CR. Oncolytic virotherapy for hematological malignancies. Adv Virol. 2012;2012:1865512.
    • Bais, S.1    Bartee, E.2    Rahman, M.M.3    McFadden, G.4    Cogle, C.R.5
  • 38
    • 0036731962 scopus 로고    scopus 로고
    • Efficient and nontoxic adenoviral purging method for autologous transplantation in breast cancer patients
    • Lillo R., Ramírez M., Alvarez A., et al. Efficient and nontoxic adenoviral purging method for autologous transplantation in breast cancer patients. Cancer Res 2002, 62:5013-5018.
    • (2002) Cancer Res , vol.62 , pp. 5013-5018
    • Lillo, R.1    Ramírez, M.2    Alvarez, A.3
  • 39
    • 0036731992 scopus 로고    scopus 로고
    • Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients
    • Wagner L.M., Guichard S.M., Burger R.A., et al. Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients. Cancer Res 2002, 62:5001-5007.
    • (2002) Cancer Res , vol.62 , pp. 5001-5007
    • Wagner, L.M.1    Guichard, S.M.2    Burger, R.A.3
  • 40
    • 0032528436 scopus 로고    scopus 로고
    • Cytosine deaminase adenoviral vector and 5-fluorocytosine selectively reduce breast cancer cells 1 million-fold when they contaminate hematopoietic cells: a potential purging method for autologous transplantation
    • Garcia-Sanchez F., Pizzorno G., Fu S.Q., et al. Cytosine deaminase adenoviral vector and 5-fluorocytosine selectively reduce breast cancer cells 1 million-fold when they contaminate hematopoietic cells: a potential purging method for autologous transplantation. Blood 1998, 92:672-682.
    • (1998) Blood , vol.92 , pp. 672-682
    • Garcia-Sanchez, F.1    Pizzorno, G.2    Fu, S.Q.3
  • 41
    • 0023227802 scopus 로고
    • The effect of attenuated vaccinia virus AS strain on multiple myeloma; a case report
    • Kawa A., Arakawa S. The effect of attenuated vaccinia virus AS strain on multiple myeloma; a case report. Jpn J Exp Med 1987, 57:79-81.
    • (1987) Jpn J Exp Med , vol.57 , pp. 79-81
    • Kawa, A.1    Arakawa, S.2
  • 42
    • 77953137806 scopus 로고    scopus 로고
    • Systemic therapy of disseminated myeloma in passively immunized mice using measles virus-infected cell carriers
    • Liu C., Russell S.J., Peng K.W. Systemic therapy of disseminated myeloma in passively immunized mice using measles virus-infected cell carriers. Mol Ther 2010, 18:1155-1164.
    • (2010) Mol Ther , vol.18 , pp. 1155-1164
    • Liu, C.1    Russell, S.J.2    Peng, K.W.3
  • 43
    • 67649700427 scopus 로고    scopus 로고
    • Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma
    • Peng K.W., Dogan A., Vrana J., et al. Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma. Am J Hematol 2009, 84:401-407.
    • (2009) Am J Hematol , vol.84 , pp. 401-407
    • Peng, K.W.1    Dogan, A.2    Vrana, J.3
  • 44
    • 70450200778 scopus 로고    scopus 로고
    • The case of oncolytic viruses versus the immune system: waiting on the judgment of Solomon
    • Prestwich R.J., Errington F., Diaz R.M., et al. The case of oncolytic viruses versus the immune system: waiting on the judgment of Solomon. Hum Gene Ther 2009, 20:1119-1132.
    • (2009) Hum Gene Ther , vol.20 , pp. 1119-1132
    • Prestwich, R.J.1    Errington, F.2    Diaz, R.M.3
  • 45
    • 85027956453 scopus 로고    scopus 로고
    • Thunder and lightning: immunotherapy and oncolytic viruses collide
    • Melcher A., Parato K., Rooney C.M., Bell J.C. Thunder and lightning: immunotherapy and oncolytic viruses collide. Mol Ther 2011, 19:1008-1016.
    • (2011) Mol Ther , vol.19 , pp. 1008-1016
    • Melcher, A.1    Parato, K.2    Rooney, C.M.3    Bell, J.C.4
  • 46
    • 14544284014 scopus 로고    scopus 로고
    • Poxvirus tropism
    • McFadden G. Poxvirus tropism. Nat Rev Microbiol 2005, 3:201-213.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 201-213
    • McFadden, G.1


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