Autologous transplantation of mobilized peripheral blood CD34+ cells selected by immunomagnetic procedures in patients with multiple myeloma

Bone Marrow Transplantation

Volumn 22, Issue 10, 1998, Pages 957-963

  Abonour, R ^a,c   Scott, K M ^a   Kunkel, L A ^b   Robertson, M J ^a   Hromas, R ^a   Graves, V ^a   Lazaridis, E N ^a   Cripe, L ^a   Gharpure, V ^a   Traycoff, C M ^a   Mills, B ^b   Srour, E F ^a   Cornetta, K ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Nexell Therapeutics Inc   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD34 selection; Immunomagnetic separation; Multiple myeloma; Transplantation

Indexed keywords

CD19 ANTIGEN; CD34 ANTIGEN; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; MELPHALAN;

ADULT; ARTICLE; CELL SEPARATION; CLINICAL ARTICLE; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; LEUKAPHERESIS; MALE; MONONUCLEAR CELL; MULTIPLE MYELOMA; MYELOMA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031754533     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701473     Document Type: Article

References (33)

1. Barliogie B, Jagannath S, Epstein J et al. Biology and therapy of multiple myeloma in 1996. Semin Hematol 1997; 34 (Suppl. 1): 67-72.
2. Gahrton G. Bone marrow and peripheral blood stem cell transplantation in multiple myeloma. Ann Oncol 1997; 8: 219-221.
3. Jagannath S, Tricot G, Barlogie B. Autotransplants in multiple myeloma: pushing the envelope. Hematol Oncol Clin N Am 1997; 11: 363-381.
4. Attal M, Harousseau JL. Stoppa AM et al. A prospective, ran- domized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. New Engl J Med 1996; 335: 91-97.
5. Cunningham D, Paz-Ares L, Gore ME et al. High-dose melphalan for multiple myeloma: long-term follow-up data. J Clin Oncol 1994; 12: 764-768.
6. Harousseau JL, Attal M, Divine M et al. Autologous stem cell transplantation after first remission induction treatment in multiple myeloma: a report of the French Registry on autologous transplantation in multiple myeloma. Blood 1995; 85: 3077-3085.
7. Fermand JP, Chevret S, Ravaud P et al. High dose chemoradiotherapy and autologous blood stem cell transplantation in multiple myeloma: results of a phase II trial involving 63 patients. Blood 1993; 82: 2005-2009.
8. Gertz MA, Witzig TE, Pineda AA et al. Monoclonal plasma cells in the blood stem cell harvest from patients with multiple myeloma are associated with shortened relapse-free survival after transplantation. Bone Marrow Transplant 1997; 19: 337-342.
9. Gazitt Y, Reading CL. Autologous transplantation with tumorfree graft: a model for multiple myeloma patients (review). Leuk Lymphoma 1996; 23: 203-212.
10. Craig JI, Langlands K, Parker AC et al. Molecular detection of tumor contamination in peripheral blood stem cell harvests. Exp Hematol 1994; 22: 898-902.
11. Vescio RA, Han EJ, Schiller GJ et al. Quantitative comparison of multiple myeloma tumor contamination in bone marrow harvest and leukapheresis autografts. Bone Marrow Transplant 1996; 18: 103-110.
12. +cells to remove circulating tumor cells. Blood 1996; 87: 1625-1634.
13. Chen BJ, Epstein J. Circulating clonal lymphocytes in myeloma constitute a minor subpopulation of B cells. Blood 1996; 87: 1972-1976.
14. + B cell precursors. Stem Cells 1994; 12: 95-102.
15. + peripheral blood progenitor cells after high-dose chemotherapy for patients with advanced multiple myeloma. Blood 1995; 86: 390-397.
16. Reece DE, Barnett MJ, Connors JM et al. Treatment of multiple myeloma with intensive chemotherapy followed by autologous BMT using marrow purged with 4-hydroperoxycyclophosphamide. Bone Marrow Transplant 1993; 11: 139-146.
17. Andersen KC, Andersen J, Soiffer R et al. Monoclonal antibody-purged bone marrow transplantation therapy for multiple myeloma. Blood 1993; 82: 2568-2576.
18. Vescio R, Hong CH, Cao J et al. The hematopoietic stem cell antigen, CD34, is not expressed on the malignant cells in multiple myeloma. Blood 1994; 84: 3283-3290.
19. + myeloma cells. Br J Haematol 1996; 93: 613-622.
20. Durie BGM, Salmon SE. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment and survival. Cancer 1975; 36: 842-854.
21. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Ann Biochem 1987; 162: 156-159.
22. Ralph QM, Brisco MJ, Joshua DE, et al. Advancement of multiple myeloma from diagnosis through plateau phase to progression does not involve a new B-cell clone: evidence from the Ig heavy chain gene. Blood 1993; 82: 202-206.
23. Ramasamy I, Brisco M, Morley A. Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms. J Clin Path 1992; 45: 770-775.
24. Trainor KJ, Brisco MJ, Story CJ et al. Monoclonality in B-lymphoproliferative disorders detected at the DNA level. Blood 1990; 75: 2220-2222.
25. Rozans MK, Smith BR, Emerson S et al. Functional assessment of T cell depletion from bone marrow prior to therapeutic transplant using limiting dilution culture methods. Transplantation 1986; 42: 380-387.
26. Cornetta K, Gharpure V, Mills B et al. Rapid engraftment after allogeneic transplanlalion using CD34-enriched marrow cells. Bone Marrow Transplant 1998; 21: 65-71.
27. Schiller G, Vescio R, Freyies C et al. Autologous CD34-selected blood progenitor cell transplants for patients with advanced multiple myeloma. Bone Marrow Transplant 1998; 21: 141-145.
28. Gazitt Y, Tian E, Barlogie B et al. Differential mobilization of myeloma cells and normal hematopoietic stem cells in multiple myeloma after treatment with cyclophosphamide and granulocyte-macrophage colony-stimulating factor. Blood 1996; 87: 805-811.
29. Lemoli RM, Cavo M, Fortuna A et al. Concomitant mobilization of plasma cells and hematopoietic progenitors into peripheral blood of patients with multiple myeloma. J Hematother 1996; 5: 339-349.
30. + stem cells do not contain clonal myeloma cells. Blood 1995; 86: 381-389.
31. Johnson RJ, Owen RG, Smith GM et al. Peripheral blood stem cell transplantation in myeloma using CD34 selected cells. Bone Marrow Transplantation 1996; 17: 723-727.
32. + cell purification: experience of 71 immunoaffinity column procedures. Bone Marrow Transplant 1997; 20: 157-162.
33. + cells for positive selection in newly diagnosed patients with myeloma. Br J Haematol 1996; 92: 263-268.