-
1
-
-
0037497184
-
A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression
-
Anest V, et al. 2003. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature. 423: 659-663.
-
(2003)
Nature
, vol.423
, pp. 659-663
-
-
Anest, V.1
-
2
-
-
30044437123
-
Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation
-
Carter RS, Pennington KN, Arrate P, Oltz EM, Ballard DW. 2005. Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation. J. Biol. Chem. 280: 43272-43279.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 43272-43279
-
-
Carter, R.S.1
Pennington, K.N.2
Arrate, P.3
Oltz, E.M.4
Ballard, D.W.5
-
3
-
-
0032589261
-
IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1
-
Chu ZL, Shin YA, Yang JM, Di Donato JA, Ballard LHDW. 1999. IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1. J. Biol. Chem. 274: 15297-15300.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15297-15300
-
-
Chu, Z.L.1
Shin, Y.A.2
Yang, J.M.3
Di Donato, J.A.4
Ballard, L.H.D.W.5
-
4
-
-
0036794398
-
BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
-
Claudio E, Brown K, Park S, Wang H, Siebenlist U. 2002. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat. Immunol. 3: 958-965.
-
(2002)
Nat. Immunol
, vol.3
, pp. 958-965
-
-
Claudio, E.1
Brown, K.2
Park, S.3
Wang, H.4
Siebenlist, U.5
-
5
-
-
18644380147
-
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
-
Dejardin E, et al. 2002. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity. 17: 525-535.
-
(2002)
Immunity
, vol.17
, pp. 525-535
-
-
Dejardin, E.1
-
6
-
-
33846024067
-
Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein
-
Durkin SS, Ward MD, Fryrear KA, Semmes OJ. 2006. Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein. J. Biol. Chem. 281: 31705-31712.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 31705-31712
-
-
Durkin, S.S.1
Ward, M.D.2
Fryrear, K.A.3
Semmes, O.J.4
-
7
-
-
34147176472
-
HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination
-
Gohda J, et al. 2007. HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination. Biochem. Biophys. Res. Commun. 357: 225-230.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 225-230
-
-
Gohda, J.1
-
8
-
-
0028889114
-
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I
-
Grossman WJ, et al. 1995. Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. U. S. A. 92: 1057-1061.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 1057-1061
-
-
Grossman, W.J.1
-
9
-
-
79952831701
-
Emerging complexity of protein ubiquitination in the NF-kappaB pathway
-
Habelhah H. 2010. Emerging complexity of protein ubiquitination in the NF-kappaB pathway. Genes Cancer. 1: 735-747.
-
(2010)
Genes Cancer
, vol.1
, pp. 735-747
-
-
Habelhah, H.1
-
10
-
-
78650915537
-
Deubiquitinases in the regulation of NFkappaB signaling
-
Harhaj EW, Dixit VM. 2011. Deubiquitinases in the regulation of NFkappaB signaling. Cell Res. 21: 22-39.
-
(2011)
Cell Res.
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
11
-
-
33947491230
-
Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase
-
Harhaj NS, Sun SC, Harhaj EW. 2007. Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase. J. Biol. Chem. 282: 4185-4192.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4185-4192
-
-
Harhaj, N.S.1
Sun, S.C.2
Harhaj, E.W.3
-
12
-
-
33645733771
-
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I
-
Hasegawa H, et al. 2006. Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I. Nat. Med. 12: 466-472.
-
(2006)
Nat. Med.
, vol.12
, pp. 466-472
-
-
Hasegawa, H.1
-
13
-
-
84856422893
-
Role of K63-linked polyubiquitination in NF-kappaB signalling: which ligase catalyzes and what molecule is targeted?
-
Hayakawa M. 2012. Role of K63-linked polyubiquitination in NF-kappaB signalling: which ligase catalyzes and what molecule is targeted? J. Biochem. 151: 115-118.
-
(2012)
J. Biochem
, vol.151
, pp. 115-118
-
-
Hayakawa, M.1
-
14
-
-
0346243941
-
Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
-
Ishitani T, et al. 2003. Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling. EMBO J. 22: 6277-6288.
-
(2003)
EMBO J.
, vol.22
, pp. 6277-6288
-
-
Ishitani, T.1
-
15
-
-
0033580931
-
Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma
-
Jin DY, Giordano V, Kibler KV, Nakano H, Jeang LHKT. 1999. Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma. J. Biol. Chem. 274: 17402-17405.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17402-17405
-
-
Jin, D.Y.1
Giordano, V.2
Kibler, K.V.3
Nakano, H.4
Jeang, L.H.K.T.5
-
16
-
-
33646164424
-
Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence
-
Kuo YL, Giam CZ. 2006. Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence. EMBO J. 25: 1741-1752.
-
(2006)
EMBO J.
, vol.25
, pp. 1741-1752
-
-
Kuo, Y.L.1
Giam, C.Z.2
-
17
-
-
27944431565
-
Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein
-
Lamsoul I, et al. 2005. Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein. Mol. Cell. Biol. 25: 10391-10406.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10391-10406
-
-
Lamsoul, I.1
-
18
-
-
50149114476
-
Human T-cell leukemia virus type 1 infection leads to arrest in the G1 phase of the cell cycle
-
Liu M, et al. 2008. Human T-cell leukemia virus type 1 infection leads to arrest in the G1 phase of the cell cycle. J. Virol. 82: 8442-8455.
-
(2008)
J. Virol
, vol.82
, pp. 8442-8455
-
-
Liu, M.1
-
19
-
-
84876864535
-
Human T-cell leukemia virus type 1 Tax protein transforms rat fibroblasts via two distinct pathways
-
Matsumoto K, et al. 1997. Human T-cell leukemia virus type 1 Tax protein transforms rat fibroblasts via two distinct pathways.
-
(1997)
-
-
Matsumoto, K.1
-
20
-
-
0030838680
-
HTLV-I provirus in the clinical subtypes of ATL
-
Matsuoka M, Tamiya S, Takemoto S, Yamaguchi K, Takatsuki K. 1997. HTLV-I provirus in the clinical subtypes of ATL. Leukemia 11(Suppl.3):67-69.
-
(1997)
Leukemia
, vol.11
, Issue.SUPPL. 3
, pp. 67-69
-
-
Matsuoka, M.1
Tamiya, S.2
Takemoto, S.3
Yamaguchi, K.4
Takatsuki, K.5
-
21
-
-
2442577087
-
Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65
-
O'Mahony AM, Montano M, Van BK, Chen LF, Greene WC. 2004. Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65. J. Biol. Chem. 279: 18137-18145.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18137-18145
-
-
O'Mahony, A.M.1
Montano, M.2
Van, B.K.3
Chen, L.F.4
Greene, W.C.5
-
22
-
-
77952060367
-
TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases
-
Parvatiyar K, Barber GN, Harhaj EW. 2010. TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases. J. Biol. Chem. 285: 14999-15009.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 14999-15009
-
-
Parvatiyar, K.1
Barber, G.N.2
Harhaj, E.W.3
-
23
-
-
6344287727
-
Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity
-
Peloponese JM, Jr, et al. 2004. Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity. J. Virol. 78:11686 -11695.
-
(2004)
J. Virol.
, vol.78
, pp. 11686-11695
-
-
Peloponese Jr, J.M.1
-
24
-
-
0025037838
-
The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells
-
Pozzatti R, Vogel J, Jay G. 1990. The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells. Mol. Cell. Biol. 10: 413-417.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 413-417
-
-
Pozzatti, R.1
Vogel, J.2
Jay, G.3
-
25
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
Senftleben U, et al. 2001. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science. 293: 1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
-
26
-
-
34548405689
-
Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling
-
Shembade N, Harhaj NS, Liebl DJ, Harhaj EW. 2007. Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling. EMBO J.. 26: 3910-3922.
-
(2007)
EMBO J.
, vol.26
, pp. 3910-3922
-
-
Shembade, N.1
Harhaj, N.S.2
Liebl, D.J.3
Harhaj, E.W.4
-
27
-
-
37049024986
-
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin conjugating enzyme Ubc13 for NF-kappaB activation
-
Shembade N, Harhaj NS, Yamamoto M, Akira S, Harhaj EW. 2007. The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin conjugating enzyme Ubc13 for NF-kappaB activation. J. Virol. 81: 13735-13742.
-
(2007)
J. Virol
, vol.81
, pp. 13735-13742
-
-
Shembade, N.1
Harhaj, N.S.2
Yamamoto, M.3
Akira, S.4
Harhaj, E.W.5
-
28
-
-
82955201670
-
Activation of the IkappaB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Taxinduced polyubiquitination
-
Shibata Y, Tanaka Y, Gohda J, Inoue J. 2011. Activation of the IkappaB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Taxinduced polyubiquitination. J. Biochem. 150: 679-686.
-
(2011)
J. Biochem.
, vol.150
, pp. 679-686
-
-
Shibata, Y.1
Tanaka, Y.2
Gohda, J.3
Inoue, J.4
-
29
-
-
0033596125
-
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases
-
Sun SC, Ballard DW. 1999. Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases. Oncogene. 18: 6948-6958.
-
(1999)
Oncogene
, vol.18
, pp. 6948-6958
-
-
Sun, S.C.1
Ballard, D.W.2
-
30
-
-
1542719918
-
Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells
-
Takeda S, et al. 2004. Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells. Int. J. Cancer. 109: 559-567.
-
(2004)
Int. J. Cancer.
, vol.109
, pp. 559-567
-
-
Takeda, S.1
-
31
-
-
27744496259
-
Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms
-
Taniguchi Y, et al. 2005. Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms. Retrovirology 2:64.
-
(2005)
Retrovirology
, vol.2
, pp. 64
-
-
Taniguchi, Y.1
-
32
-
-
0032516520
-
NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation
-
Uhlik M, et al. 1998. NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation. J. Biol. Chem. 273: 21132-21136.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21132-21136
-
-
Uhlik, M.1
-
33
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M. 2009. Regulation and function of NF-kappaB transcription factors in the immune system. Annu. Rev. Immunol. 27: 693-733.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
34
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, et al. 2001. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 412: 346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
-
35
-
-
34247869875
-
Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK
-
Wu X, Sun SC. 2007. Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK. EMBO Rep. 8: 510-515.
-
(2007)
EMBO Rep.
, vol.8
, pp. 510-515
-
-
Wu, X.1
Sun, S.C.2
-
36
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
Xiao G, Harhaj EW, Sun SC. 2001. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol. Cell. 7: 401-409.
-
(2001)
Mol. Cell.
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
37
-
-
0034718693
-
Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein
-
Xiao G, Sun SC. 2000. Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein. Oncogene. 19: 5198-5203.
-
(2000)
Oncogene
, vol.19
, pp. 5198-5203
-
-
Xiao, G.1
Sun, S.C.2
-
38
-
-
0038511129
-
Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression
-
Yamamoto Y, Verma UN, Prajapati S, Kwak YT, Gaynor RB. 2003. Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. Nature. 423: 655-659.
-
(2003)
Nature
, vol.423
, pp. 655-659
-
-
Yamamoto, Y.1
Verma, U.N.2
Prajapati, S.3
Kwak, Y.T.4
Gaynor, R.B.5
-
39
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
-
Yamaoka S, et al. 1998. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell. 93: 1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
-
40
-
-
0029670843
-
Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein
-
Yamaoka S, et al. 1996. Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein. EMBO J. 15:873- 887.
-
(1996)
EMBO J
, vol.15
, pp. 873-887
-
-
Yamaoka, S.1
-
41
-
-
33746210147
-
Versatile reporter systems show that transactivation by human T-cell leukemia virus type 1 Tax occurs independently of chromatin remodeling factor BRG1
-
Zhang L, Liu M, Merling R, Giam CZ. 2006. Versatile reporter systems show that transactivation by human T-cell leukemia virus type 1 Tax occurs independently of chromatin remodeling factor BRG1. J. Virol. 80: 7459-7468.
-
(2006)
J. Virol
, vol.80
, pp. 7459-7468
-
-
Zhang, L.1
Liu, M.2
Merling, R.3
Giam, C.Z.4
-
42
-
-
65749093789
-
Induction of p21(CIP1/WAF1) expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization
-
Zhang L, Zhi H, Liu M, Kuo YL, Giam CZ. 2009. Induction of p21(CIP1/WAF1) expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization. Retrovirology 6:35.
-
(2009)
Retrovirology
, vol.6
, pp. 35
-
-
Zhang, L.1
Zhi, H.2
Liu, M.3
Kuo, Y.L.4
Giam, C.Z.5
-
43
-
-
79955757521
-
NF-kappaB hyperactivation by HTLV-1 Tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ
-
doi:10.1371/journal. ppat.1002025
-
Zhi H, et al. 2011. NF-kappaB hyperactivation by HTLV-1 Tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ. PLoS Pathog. 7:e1002025. doi:10.1371/journal. ppat.1002025.
-
(2011)
PLoS Pathog
, vol.7
-
-
Zhi, H.1
|