-
1
-
-
33744910363
-
Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells
-
Babu G, Waterfield M, Chang M, Wu X, Sun S-C (2006) Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells. J Biol Chem 281: 14041-14047
-
(2006)
J Biol Chem
, vol.281
, pp. 14041-14047
-
-
Babu, G.1
Waterfield, M.2
Chang, M.3
Wu, X.4
Sun, S.-C.5
-
2
-
-
0032888951
-
Phosphorylation of the human T-cell leukemia virus type 1 transactivator Tax on adjacent serine residues is critical for Tax activation
-
Bex F, Murphy K, Wattiez R, Burny A, Gaynor RB (1999) Phosphorylation of the human T-cell leukemia virus type 1 transactivator Tax on adjacent serine residues is critical for Tax activation. J Virol 73: 738-745
-
(1999)
J Virol
, vol.73
, pp. 738-745
-
-
Bex, F.1
Murphy, K.2
Wattiez, R.3
Burny, A.4
Gaynor, R.B.5
-
3
-
-
33645977821
-
Ubiquitin, TAK1 and IKK: Is there a connection?
-
Chen ZJ, Bhoj V, Seth RB (2006) Ubiquitin, TAK1 and IKK: Is there a connection? Cell Death Differ 13: 687-692
-
(2006)
Cell Death Differ
, vol.13
, pp. 687-692
-
-
Chen, Z.J.1
Bhoj, V.2
Seth, R.B.3
-
4
-
-
0032589261
-
IKKγ mediates the interaction of cellular IκB kinases with the Tax transforming protein of human T cell leukemia virus type 1
-
Chu Z-L, Shin Y-A, Yang J-M, DiDonato JA, Ballard DW (1999) IKKγ mediates the interaction of cellular IκB kinases with the Tax transforming protein of human T cell leukemia virus type 1. J Biol Chem 274: 15297-15300
-
(1999)
J Biol Chem
, vol.274
, pp. 15297-15300
-
-
Chu, Z.-L.1
Shin, Y.-A.2
Yang, J.-M.3
DiDonato, J.A.4
Ballard, D.W.5
-
5
-
-
33646034316
-
Activation of IKK by TNFβ requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ (2006) Activation of IKK by TNFβ requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 22: 245-257
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
6
-
-
0031813289
-
Human T-cell leukemia virus type 1 Tax induction of NF-κB involves activation of the IkB kinase α (IKKα) and IKKβ cellular kinases
-
Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham Jr ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC (1998) Human T-cell leukemia virus type 1 Tax induction of NF-κB involves activation of the IkB kinase α (IKKα) and IKKβ cellular kinases. Mol Cell Biol 18 5157-5165
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5157-5165
-
-
Geleziunas, R.1
Ferrell, S.2
Lin, X.3
Mu, Y.4
Cunningham Jr, E.T.5
Grant, M.6
Connelly, M.A.7
Hambor, J.E.8
Marcu, K.B.9
Greene, W.C.10
-
7
-
-
25444478908
-
Molecular mechanisms of cellular transformation by HTLV-1 Tax
-
Grassmann R, Aboud M, Jeang KT (2005) Molecular mechanisms of cellular transformation by HTLV-1 Tax. Oncogene 24: 5976-5985
-
(2005)
Oncogene
, vol.24
, pp. 5976-5985
-
-
Grassmann, R.1
Aboud, M.2
Jeang, K.T.3
-
8
-
-
0033551607
-
IKKγ serves as a docking subunit of the Iκβ kinase and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
-
Harhaj EW, Sun S-C (1999) IKKγ serves as a docking subunit of the Iκβ kinase and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. J Biol Chem 274: 22911-22914
-
(1999)
J Biol Chem
, vol.274
, pp. 22911-22914
-
-
Harhaj, E.W.1
Sun, S.-C.2
-
9
-
-
0034624810
-
Somatic mutagenesis studies of NF-κB signaling in human T cells: Evidence for an essential role of IKKγ in NF-κB activation by T-cell costimulatory signals and HTLV-I Tax protein
-
Harhaj EW, Good L, Xiao G-T, Uhlik M, Cvijic ME, Rivera I, Sun S-C (2000) Somatic mutagenesis studies of NF-κB signaling in human T cells: evidence for an essential role of IKKγ in NF-κB activation by T-cell costimulatory signals and HTLV-I Tax protein. Oncogene 19: 1386-1391
-
(2000)
Oncogene
, vol.19
, pp. 1386-1391
-
-
Harhaj, E.W.1
Good, L.2
Xiao, G.-T.3
Uhlik, M.4
Cvijic, M.E.5
Rivera, I.6
Sun, S.-C.7
-
10
-
-
0035139943
-
Hostile takeovers: Viral appropriation of the NF-κB pathway
-
Hiscott J, Kwon H, Genin P (2001) Hostile takeovers: Viral appropriation of the NF-κB pathway. J Clin Invest 107: 143-151
-
(2001)
J Clin Invest
, vol.107
, pp. 143-151
-
-
Hiscott, J.1
Kwon, H.2
Genin, P.3
-
11
-
-
0033580931
-
Role of adaptor function in oncoprotein-mediated activation of NF-κB: HTLV-I Tax interacts directly with IκB kinase γ
-
Jin D-Y, Giordano V, Kibler KV, Nakano H, Jeang K-T (1999) Role of adaptor function in oncoprotein-mediated activation of NF-κB: HTLV-I Tax interacts directly with IκB kinase γ. J Biol Chem 274: 17402-17405
-
(1999)
J Biol Chem
, vol.274
, pp. 17402-17405
-
-
Jin, D.-Y.1
Giordano, V.2
Kibler, K.V.3
Nakano, H.4
Jeang, K.-T.5
-
12
-
-
4344712350
-
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
-
Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, Chiu YH, Deng L, Chen ZJ (2004) TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains. Mol Cell 15: 535-548
-
(2004)
Mol Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
Ea, C.K.4
Hong, M.5
Shaito, A.6
Chiu, Y.H.7
Deng, L.8
Chen, Z.J.9
-
13
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin M, Ben-Neriah Y (2000) Phosphorylation meets ubiquitination: The control of NF-κB activity. Annu Rev Immunol 18: 621-663
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
14
-
-
0036009115
-
NF-κB at the crossroads of life and death
-
Karin M, Lin A (2002) NF-κB at the crossroads of life and death. Nat Immunol 3: 221-227
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
15
-
-
33744951304
-
Ubiquitination of RIP is required for tumor necrosis factor α-induced NF-κB activation
-
Li H, Kobayashi M, Blonska M, You Y, Lin X (2006) Ubiquitination of RIP is required for tumor necrosis factor α-induced NF-κB activation. J Biol Chem 281: 13636-13643
-
(2006)
J Biol Chem
, vol.281
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
17
-
-
0029955714
-
The pCL vector system: Rapid production of helper-free high-titer, recombinant retroviruses
-
Naviaux RN, Costanzi E, Haas M, Verma IM (1996) The pCL vector system: rapid production of helper-free high-titer, recombinant retroviruses. J Virol 70: 5701-5705
-
(1996)
J Virol
, vol.70
, pp. 5701-5705
-
-
Naviaux, R.N.1
Costanzi, E.2
Haas, M.3
Verma, I.M.4
-
18
-
-
17944363168
-
Genome-wide expression changes induced by HTLV-1 Tax: Evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-κB activation
-
Ng PW et al (2001) Genome-wide expression changes induced by HTLV-1 Tax: Evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-κB activation. Oncogene 20: 4484-4496
-
(2001)
Oncogene
, vol.20
, pp. 4484-4496
-
-
PW, N.1
-
19
-
-
0033580466
-
The kinase TAK1 can activate the NIK-I κB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K (1999) The kinase TAK1 can activate the NIK-I κB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398: 252-256
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
20
-
-
33745851830
-
TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis
-
Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J (2006) TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. J Biol Chem 281: 19610-19617
-
(2006)
J Biol Chem
, vol.281
, pp. 19610-19617
-
-
Omori, E.1
Matsumoto, K.2
Sanjo, H.3
Sato, S.4
Akira, S.5
Smart, R.C.6
Ninomiya-Tsuji, J.7
-
21
-
-
11244341060
-
Tumor suppressor negatively regulates JNK signaling pathway downstream of TNFR members
-
Reiley W, Zhang M, Sun S-C (2004) Tumor suppressor negatively regulates JNK signaling pathway downstream of TNFR members. J Biol Chem 279: 55161-55167
-
(2004)
J Biol Chem
, vol.279
, pp. 55161-55167
-
-
Reiley, W.1
Zhang, M.2
Sun, S.-C.3
-
22
-
-
0032993635
-
Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone
-
Robek MD, Ratner L (1999) Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone. J Virol 73: 4856-4865
-
(1999)
J Virol
, vol.73
, pp. 4856-4865
-
-
Robek, M.D.1
Ratner, L.2
-
23
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Matsumoto K, Takeuchi O, Akira S (2005) Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol 6: 1095-1987
-
(2005)
Nat Immunol
, vol.6
, pp. 1095-1987
-
-
Sato, S.1
Sanjo, H.2
Takeda, K.3
Ninomiya-Tsuji, J.4
Yamamoto, M.5
Kawai, T.6
Matsumoto, K.7
Takeuchi, O.8
Akira, S.9
-
24
-
-
33748999526
-
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells
-
Sato S, Sanjo H, Tsujimura T, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Takeuchi O, Akira S (2006) TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells. Int Immunol 18: 1405-1411
-
(2006)
Int Immunol
, vol.18
, pp. 1405-1411
-
-
Sato, S.1
Sanjo, H.2
Tsujimura, T.3
Ninomiya-Tsuji, J.4
Yamamoto, M.5
Kawai, T.6
Takeuchi, O.7
Akira, S.8
-
25
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim JH et al (2005) TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev 19: 2668-2681
-
(2005)
Genes Dev
, vol.19
, pp. 2668-2681
-
-
Shim, J.H.1
-
26
-
-
0025245774
-
Identification of HTLV-1 tax transactivator mutants exhibiting novel transcriptional phenotypes
-
Smith MR, Greene WC (1990) Identification of HTLV-1 tax transactivator mutants exhibiting novel transcriptional phenotypes. Genes Dev 4: 1875-1885
-
(1990)
Genes Dev
, vol.4
, pp. 1875-1885
-
-
Smith, M.R.1
Greene, W.C.2
-
27
-
-
0021719086
-
Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines
-
Smith SD, Shatsky M, Cohen PS, Warnke R, Link MP, Glader BE (1984) Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines. Cancer Res 44: 5657-5660
-
(1984)
Cancer Res
, vol.44
, pp. 5657-5660
-
-
Smith, S.D.1
Shatsky, M.2
Cohen, P.S.3
Warnke, R.4
Link, M.P.5
Glader, B.E.6
-
28
-
-
2342629277
-
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
-
Sun L, Deng L, Ea C-K, Xia Z-P, Chen ZJ (2004) The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 14: 289-301
-
(2004)
Mol Cell
, vol.14
, pp. 289-301
-
-
Sun, L.1
Deng, L.2
Ea, C.-K.3
Xia, Z.-P.4
Chen, Z.J.5
-
29
-
-
0033596125
-
Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: Hijacking cellular IκB kinases
-
Sun S-C, Ballard DW (1999) Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: Hijacking cellular IκB kinases. Oncogene 18: 6948-6958
-
(1999)
Oncogene
, vol.18
, pp. 6948-6958
-
-
Sun, S.-C.1
Ballard, D.W.2
-
30
-
-
25444459429
-
Activation of NF-κB by HTLV-I and implications for cell transformation
-
Sun S-C, Yamaoka S (2005) Activation of NF-κB by HTLV-I and implications for cell transformation. Oncogene 24: 5952-5964
-
(2005)
Oncogene
, vol.24
, pp. 5952-5964
-
-
Sun, S.-C.1
Yamaoka, S.2
-
31
-
-
0032516520
-
NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I Tax-mediated NF-κB activation
-
Uhlik M, Good L, Xiao G, Harhaj EW, Zandi E, Karin M, Sun S-C (1998) NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I Tax-mediated NF-κB activation. J Biol Chem 273: 21132-21136
-
(1998)
J Biol Chem
, vol.273
, pp. 21132-21136
-
-
Uhlik, M.1
Good, L.2
Xiao, G.3
Harhaj, E.W.4
Zandi, E.5
Karin, M.6
Sun, S.-C.7
-
32
-
-
33746111852
-
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
-
Wan YY, Chi H, Xie M, Schneider MD, Flavell RA (2006) The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. Nat Immunol 7: 851-858
-
(2006)
Nat Immunol
, vol.7
, pp. 851-858
-
-
Wan, Y.Y.1
Chi, H.2
Xie, M.3
Schneider, M.D.4
Flavell, R.A.5
-
33
-
-
0034514655
-
Ubiquitination and deubiquitination: Targeting of proteins for degradation by the proteasome
-
Wilkinson KD (2000) Ubiquitination and deubiquitination: Targeting of proteins for degradation by the proteasome. Semin Cell Dev Biol 11: 141-148
-
(2000)
Semin Cell Dev Biol
, vol.11
, pp. 141-148
-
-
Wilkinson, K.D.1
-
34
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD (2006) Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation. Nat Cell Biol 8: 398-406
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
35
-
-
0035064503
-
Multiple viral strategies of HTLV-1 for dysregulation of cell growth control
-
Yoshida M (2001) Multiple viral strategies of HTLV-1 for dysregulation of cell growth control. Annu Rev Immunol 19: 475-496
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 475-496
-
-
Yoshida, M.1
-
36
-
-
0345826149
-
BcI10 activates the NF-κB pathway through ubiquitination of NEMO
-
Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M, Xiao W, Dixit VM (2004) BcI10 activates the NF-κB pathway through ubiquitination of NEMO. Nature 427: 167-171
-
(2004)
Nature
, vol.427
, pp. 167-171
-
-
Zhou, H.1
Wertz, I.2
O'Rourke, K.3
Ultsch, M.4
Seshagiri, S.5
Eby, M.6
Xiao, W.7
Dixit, V.M.8
|