The roots of Atractylodes japonica Koidzumi promote adipogenic differentiation via activation of the insulin signaling pathway in 3T3-L1 cells

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Han, Yunkyung ^a   Jung, Hyo W ^a   Park, Yong Ki ^a,b  

^a Dongguk University   (South Korea)

^b Dongguk University   (South Korea)

Author keywords

3T3 L1 adipocyte; Atractylodes japonica; Atractylodis Rhizoma Alba; GLUT4; Insulin; PPAR ; Type 2 diabetes

Indexed keywords

ANTIDIABETIC AGENT; ATRACTYLODES JAPONICA KOIDZUMI EXTRACT; GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANTIDIABETIC ACTIVITY; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GLUCOSE TRANSPORT; LIPID STORAGE; MEDICINAL PLANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT ROOT; PROADIPOCYTE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84866142913     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-154     Document Type: Article

References (22)

1. Prentki M, Nolan CJ. Islet β cell failure in type 2 diabetes. J Clin Invest 2006, 116:1802-1812. 10.1172/JCI29103, 1483155, 16823478.
2. Zhou J, Zhou S. Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes. Eur J Pharmacol 2010, 649:390-397. 10.1016/j.ejphar.2010.09.030, 20868663.
3. Castan-Laurell I, Dray C, Knauf C, Kunduzova O, Valet P. Apelin, a promising target for type 2 diabetes treatment?. Trends Endocrinol Metab 2012, 23:234-241. 10.1016/j.tem.2012.02.005, 22445464.
4. Burén J, Liu HX, Lauritz J, Eriksson JW. High glucose and insulin in combination cause insulin receptor substrate-1 and -2 depletion and protein kinase B desensitization in primary cultured rat adipocytes: possible implication for insulin resistance in type 2 diabetes. Eur J Endocrinol 2003, 148:157-167. 10.1530/eje.0.1480157, 12534369.
5. Xue P, Hou Y, Zhang Q, Woods CG, Yarborough K, Liu H, Sun G, Anderson ME, Pi J. Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response. Biochem Biophys Res Commun 2011, 407:360-365. 10.1016/j.bbrc.2011.03.024, 3086019, 21396911.
6. Ahn J, Lee H, Kim S, Ha T. Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/β-catenin signaling. Am J Physiol Cell Physiol 2010, 298:1510-1516.
7. Liu J, Lin H, Cheng P, Hu X, Lu H. Effects of ghrelin on the proliferation and differentiation of 3T3-L1 preadipocytes. J Huazhong Univ Sci Technol 2009, 29:227-230.
8. Kim CK, Kim M, Oh SD, Lee SM, Sun B, Choi GS, Kim SK, Bae H, Kang C, Min BI. Effects of Atractylodes macrophala Koidzumi rhizome on 3T3-L1 adipogenesis and an animal model of obesity. J Ethnopharmacol 2011, 137:396-402. 10.1016/j.jep.2011.05.036, 21669278.
9. Zhang WY, Lee JJ, Kim IS, Kim Y, Park JS, Myung CS. 7-O-Methylaromadendrin stimulates glucose uptake and improves insulin resistance in vitro. Biol Pharm Bull 2010, 33:1494-1499. 10.1248/bpb.33.1494, 20823563.
10. Xu C, Wang LL, Liu HY, Zhou XB, Cao YL, Li S. C33H, a novel PPARα/γ dual agonist, has beneficial effects on insulin resistance and lipid metabolism. Acta Pharmacol Sin 2006, 27:223-228. 10.1111/j.1745-7254.2006.00263.x, 16412273.
11. Choi K, Kim YB. Molecular mechanism of insulin resistance in obesity and type 2 diabetes. Korean J Intern Med 2010, 25:119-129. 10.3904/kjim.2010.25.2.119, 2880683, 20526383.
12. Lee SH, Lee HJ, Lee YH, Lee BW, Cha BS, Kang ES, Ahn CW, Park JS, Kim HJ, Lee EY. Korean red ginseng (panax ginseng) improves insulin sensitivity in high fat fed Sprague-Dawley rats. Phytother Res 2012, 26:142-147. 10.1002/ptr.3610, 22034219.
13. Kim D, Park KK, Lee SK, Lee SE, Hwang JK. Cornus kousa f. buerger ex miquel increases glucose uptake through activation of peroxisome proliferator-activated receptor gamma and insulin sensitization. J Ethnopharmacol 2011, 133:803-809. 10.1016/j.jep.2010.11.007, 21070843.
14. Hong MH, Kim JH, Bae H, Lee NY, Shin YC, Kim SH, Ko SG. Atractylodes japonica koidzumi inhibits the production of proinflammatory cytokines through inhibition of the NF-kappaB/IkappaB signal pathway in HMC-1 human mast cells. Arch Pharm Res 2010, 33:843-851. 10.1007/s12272-010-0606-6, 20607488.
15. Wang KT, Chen LG, Wu CH, Chang CC, Wang CC. Gastroprotective activity of atractylenolide III from Atractylodes ovate on ethanol-induced gastric ulcer in vitro and in vivo. J Pharm Pharmacol 2010, 62:381-388.
16. Wang KT, Chen LG, Chou DS, Liang WL, Wang CC. Anti-oxidative abilities of essential oils from Atractylodes ovate rhizome. Evid Based Complement Alternat Med 2011,
17. Lee OH, Lee HH, Kim JH, Lee BY. Effect of ginsenosides Rg3 and Re on glucose transport in mature 3T3-L1 adipocytes. Phytother Res 2011, 25:768-773.
18. Ikarashi N, Tajima M, Suzuki K, Toda T, Ito K, Ochiai W, Sugiyama K. Inhibition of preadipocyte differentiation and lipid accumulation by orengedokuto treatment of 3T3-L1 cultures. Phytother Res 2012, 26:91-100. 10.1002/ptr.3493, 21557367.
19. Sharma AM, Staels B. Peroxisome proliferator-activated receptor gamma and adipose tissue-understanding obesity-related changes in regulation of lipid and glucose metabolism. J Clin Endocrinol Metab 2007, 92:386-395.
20. Yang Y, Shang W, Zhou L, Jiang B, Jin H, Chen M. Emodin with PPARγ ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-L1 cells. Biochem Biophys Res Commun 2007, 353:225-230. 10.1016/j.bbrc.2006.11.134, 17174269.
21. Cho KW, Lee OH, Banz WJ, Moustaid-Moussa N, Shay NF, Kim YC. Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARgamma transcriptional activity. J Nutr Biochem 2010, 21:841-847. 10.1016/j.jnutbio.2009.06.012, 19775880.
22. Oliver E, McGillicuddy F, Phillips C, Toomey S, Roche HM. The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA. Proc Nutr Soc 2010, 69:232-243. 10.1017/S0029665110000042, 20158940.