FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility

Science Signaling

Volumn 5, Issue 240, 2012, Pages

  Siesser, Priscila F ^a   Motolese, Marta ^b,d   Walker, Matthew P ^a   Goldfarb, Dennis ^a,c   Gewain, Kelly ^a   Yan, Feng ^a   Kulikauskas, Rima M ^b   Chien, Andy J ^b   Wordeman, Linda ^b   Major, Michael B ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c CB 3175 Sitterson Hall   (United States)

^d IRCCS NEUROMED   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FAM123A PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR ARHGEF2; MYOSIN ADENOSINE TRIPHOSPHATASE; PROTEIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MASS SPECTROMETRY; MICROTUBULE; MUSCLE CONTRACTILITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ACTOMYOSIN; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; CHROMATOGRAPHY, AFFINITY; FOCAL ADHESIONS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MASS SPECTROMETRY; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; PROTEIN INTERACTION MAPPING; TUMOR SUPPRESSOR PROTEINS;

EID: 84866133046     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002871     Document Type: Article

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