Nicorandil Prevents Right Ventricular Remodeling by Inhibiting Apoptosis and Lowering Pressure Overload in Rats with Pulmonary Arterial Hypertension

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Zuo, Xiang Rong ^a   Wang, Qiang ^a   Cao, Quan ^a   Yu, Yan Zhe ^a   Wang, Hui ^a   Bi, Li Qing ^a   Xie, Wei Ping ^a   Wang, Hong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYDECANOIC ACID; BRAIN NATRIURETIC PEPTIDE; MONOCROTALINE; NICORANDIL; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; HEART LEFT VENTRICLE OVERLOAD; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART RIGHT VENTRICLE; HEART RIGHT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE PRESSURE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HISTOPATHOLOGY; MALE; MORTALITY; NONHUMAN; PULMONARY HYPERTENSION; RAT; SURVIVAL RATE; SYSTOLIC BLOOD PRESSURE; TREATMENT DURATION; WEIGHT GAIN;

ANIMALS; ANTIHYPERTENSIVE AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERTENSION, PULMONARY; IN SITU NICK-END LABELING; NATRIURETIC PEPTIDE, BRAIN; NICORANDIL; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; VENTRICULAR REMODELING;

RATTUS;

EID: 84866129433     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044485     Document Type: Article

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