IL-17A levels increase in the infarcted region of the left ventricle in a rat model of myocardial infarction

Biological Research

Volumn 45, Issue 2, 2012, Pages 193-200

  Ávalos, Ana María ^a   Apablaza, Felipe A ^a   Quiroz, Mariana ^a   Toledo, Viviana ^a   Peña, Juan Pedro ^b   Michea, Luis ^b   Irarrázabal, Carlos E ^a   Carrión, Flavio A ^a   Figueroa, Fernando E ^a  

^a UNIVERSIDAD DE LOS ANDES   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Cardiovascular disease; Interleukin 17; Myocardial infarction; Th17

Indexed keywords

ANIMALIA; RATTUS;

EID: 84866089613     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602012000200012     Document Type: Article

References (37)

1. AGGARWAL S, GHILARDI N, XIE MH, DE SAUVAGE FJ, GURNEY AL (2003) Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 278:1910-1914.
2. AWASTHI A, KUCHROO VK (2009) Th17 cells: from precursors to players in inflammation and infection. Int Immunol 21:489-498.
3. BAIDYA SG, ZENG QT (2005) Helper T cells and atherosclerosis: the cytokine web. Postgrad Med J 8:1746-1752.
4. BALDEVIANO GC, BARIN JG, TALOR MV, SRINIVASAN S, BEDJA D, ZHENG D, GABRIELSON K, IWAKURA Y, ROSE NR, CIHAKOVA D (2010) Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy. Circ Res 106:1646-1655.
5. BARRY SP, OUNZAIN S, McCORMICK J, SCARABELLI TM, CHENSCARABELLI C, SARAVOLATZ LII, FAGGIAN G, MAZZUCCO A, SUZUKI H, THIEMERMANN C, KNIGHT RA, LATCHMAN DS, STEPHANOU A (2011) Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury. Int J Cardiol Oct 24. http://dx.doi. org/10.1016/j.ijcard.2011.08.849
6. BHINDI R, WITTING PK, MCMAHON AC, KHACHIGIAN LM, LOWE HC (2006) Rat models of myocardial infarction. Pathogenetic insights and clinical relevance. Thromb Haemost 96:602-610.
7. CHEN S, SHIMADA K, ZHANG W, HUANG G, CROTHER TR, ARDITI M (2010) IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice. J Immunol 185:5619-5627.
8. CHEN Y, LANGRISH CL, MCKENZIE B, JOYCE-SHAIKH B, STUMHOFER JS, MCCLANAHAN T, BLUMENSCHEIN W, CHURAKOVSA T, LOW J, PRESTA L, HUNTER CA, KASTELEIN RA, CUA DJ (2006) Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest 116:1317-1326.
9. CHEN Z, LIN F, GAO Y, LI Z, ZHANG J, XING Y, DENG Z, YAO Z, TSUN A, LI B (2011) FOXP3 and RORγt: Transcriptional regulation of Treg and Th17. In Immunopharmacol 11:536-542.
10. CHENG X, LIAO YH, GE H, LI B, ZHANG J, YUAN J, WANG M, LIU Y, GUO Z, CHEN J, ZHANG J, ZHANG L (2005) Th1/Th2 functional imbalance after acute myocardial infarction: coronary arterial inflammation or myocardial inflammation. J Clin Immunol 25:246-253.
11. CHENG X, YU X, DING YJ, FU QQ, XIE JJ, TANG TT, YAO R, CHEN Y, LIAO YH (2008) The Th17/Treg imbalance in patients with acute coronary syndrome. Clin Immunol 127:89-97.
12. CORTEZ DM, FELDMAN MD, MUMMIDI S, VALENTE AJ, STEFFENSEN B, VINCENTI M, BARNES JL, CHANDRASEKAR B (2007) IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK and ERK1/2-dependent C/EBP-beta, NF-kappaB, and AP-1 activation. Am J Physiol Heart Circ Physiol 293: H3356-3365.
13. DETEN A, VOLZ HC, BRIEST W, ZIMMER HG (2002) Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. Card Res 55:329-340.
14. FISHBEIN MC, MACLEAN D, MAROKO PR (1978) Experimental myocardial infarction in the rat. Am J Pathol 90:57-70.
15. FRANGOGIANNIS N (2012) Regulation of the Inflammatory Response in Cardiac Repair. Circ Res 110:159-173.
16. HARRINGTON LE, HATTON RD, MANGAN PR, TURNER H, MURPHY TL, MURPHY KM, WEAVER CT (2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunol 6:1123-1132.
17. HASHMI S, ZENG QT (2006) Role of interleukin-17 and interleukin-17-induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease. Coron Artery Dis 17:699-706.
18. JAFARZADEH A, ESMAEELI-NADIMI A, NOUGH H, NEMATI M, REZAYATI MT (2009) Serum levels of interleukin (IL)-13, IL-17 and IL-18 in patients with isquemic heart disease. Anadolu Kardiyol Derg 9:75-83.
19. LANGRISH CL, CHEN Y, BLUMENSCHEIN WM, MATTSON J, BASHAM B, SEDGWICK JD, MCCLANAHAN T, KASTELEIN RA, CUA DJ (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201:233-240.
20. LEVINE B, KALMAN J, MAYER L, FILLIT HM, PACKER M (1990) Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. New Eng J Med 323:236-241.
21. LI B, LIAO YH, CHENG X, GE H, GUO H, WANG M (2006) Effects of carvedilol on cardiac cytokines expression and remodelling in rat with acute myocardial infarction. Int J Cardiol 111:247-255.
22. LIANG J, ZHENG Z, WANG M, HAN L, ZHENG Z, PENG J, LIU Z, WEI Y (2009) Myeloperoxidase (MPO) and interleukin-17 (IL-17) plasma levels are increased in patients with acute coronary syndromes. J Int Med Res 37:862-866.
23. LIAO YH, XIA N, ZHOU SF, TANG TT, YAN XX, LV BJ, NIE SF, WANG J, IWAKURA Y, XIAO H, YUAN J, JEVALLEE H, WEI F, SHI GP, CHENG X (2012) Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration J Am Coll Cardiol 24:420-429.
24. MANGAN PR, HARRINGTON LE, O'QUINN DB, HELMS WS, BULLARD DC, ELSON CO, HATTON RD, WAHL SM, SCHOEB TR, WEAVER CT (2006) Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441:231-234.
25. MANN DL (2009) Inflammatory mediators and the failing heart, Past, present and the foreseeable future Circ Res 91:988-998.
26. METHE H, BRUNNER S, WIEGAND D, NABAUER M, KOGLIN J, EDELMAN ER (2005) Enhanced T-helper-1 lymphocyte activation patterns in acute coronary syndromes. J Am College Cardiol 45:1939-1945.
27. NIAN M, LEE P, KHAPER N, LIU P (2004) Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res 94:1543-1553.
28. ONO K, MATSUMORI A, SHIOI T, FURUKAWA Y, SASAYAMA S (1998) Cytokine gene expression after myocardial infarction in rat hearts. Circ 98:149-156.
29. PARK H, LI Z, YANG XO, CHANG SH, NURIEVA R, WANG YH, WANG Y, HOOD L, ZHU Z, TIAN Q, DONG C (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunol 6:1133-1141.
30. PASQUI AL, RENZO MD, PUCCETTI AL (2005) Cytokines in acute coronary syndromes. Int J Cardiol 105:355-356.
31. PFEFFER MA, PFEFFER JM, FISHBEIN MC, FLETCHER PJ, SPADARO J, KLONER RA, BRAUNWALD E (1979) Myocardial infarct size and ventricular function in rats. Circ Res 44:503-512.
32. SCHOEMAKER RG, URQUHART J, DEBETS JJ, STRUYKER BOUDIER HA, SMITS JF (1990) Acute hemodynamic effects of coronary artery ligation in conscious rats. Basic Res Cardiol 85:9-20.
33. STEPPICH BA, MOOG P, MATISSEK C, WISNIOWSKI N, KÜHLE J, JOGHETAEI N, NEUMANN FJ, SCHOMIG A, OTT I (2007) Cytokine profiles and T cell function in acute coronary syndromes. Atheros 190:443-451.
34. THYGESEN K, ALPERT JS (2007) White HD on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Redifinition of Myocardial Infarction. Universal definition of myocardial infarction. Eur Heart J 28:2525-2538.
35. TIMMERS L, SLUIJTER JP, VAN KEULEN JK, HOEFER IE, NEDERHOFF MG, GOUMANS MJ, DOEVENDANS PA, VAN ECHTELD CJ, JOLES JA, QUAX PH, PIEK JJ, PASTERKAMP G, DE KLEIJN DP (2008) Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res 102:257-264.
36. YI A, JIAN L, XIAOJING H, HUI X (2009) The prevalence of Th17 cells in patients with dilated cardiomyopathy. Clin Invest Med. 32:E144-E150.
37. YIN FC, SPURGEON HA, RAKUSAN K, WEISFELDT ML, LAKATTA EG (1982) Use of tibial length to cuantify cardiac hypertrophy: application in the aging rat. AJP-Heart 243: H941-H947.