Variation in concentrations of major bioactive compounds in Prunella vulgaris L. related to plant parts and phenological stages

Biological Research

Volumn 45, Issue 2, 2012, Pages 171-175

  Chen, Yuhang ^a,b   Zhu, Zaibiao ^a   Guo, Qiaosheng ^a   Zhang, Lixia ^a   Zhang, Xiaoming ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

Author keywords

Oleanolic acid; Ontogenetic and morphogenetic variation; Prunella vulgaris L.; Rosmarinic acid; Ursolic acid

Indexed keywords

LAMIACEAE; PRUNELLA (ANGIOSPERM); PRUNELLA VULGARIS;

EID: 84866084828     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602012000200009     Document Type: Article

References (47)

1. AYAN AK, YANAR P, CIRAK C, BILGENER M (2007) Morphogenetic and diurnal variation of total phenols in some Hypericum species from Turkey during their phenological cycles. Bangladesh J Bot 36: 39-46.
2. BOARD of PHARMACOPOEIA of P.R. CHINA (ed) (2010) Pharmacopoeia of the People's Republic of China. Chinese Edition 2010, Part I. China Medico-Pharmaceutical Science & Technology Puhlishig House. Beijing, pp: 263.
3. CHEN SQ, DONG CM, ZHENG XK, DONG SL, WANG L, FENG WS (2003) The quantitative variety of rosmarinic acid in Rabdosia rubescens from different harvesting time. J Henan Univ Chin Med 18: 28-30.
4. CHEN YH, GUO QS, LIU L, LIAO L, ZHU ZB (2011) Influence of fertilization and drought stress on the growth and production of secondary metabolites in Prunella vulgaris L. J Med Plant Res 5: 1749-1755.
5. CHEN YH, GUO QS, ZHU ZB, ZHANG LX (2012) Changes in bioactive components related to the harvest time from the spicas of Prunella vulgaris. Pharm Biol, DOI: 10.3109/13880209.2012.658477.
6. CHEN YH, GUO QS, WANG CY (2010) Textual research on change of medicinal parts and herbal medicine of Prunella vulgaris. Chin J Chin Materia Med 35: 242-246.
7. CHEUNG HY, ZHANG QF (2008) Enhanced analysis of triterpenes, flavonoids and phenolic compounds in Prunella vulgaris L. by capillary zone electrophoresis with the addition of running buffer modifiers. J Chromatogr A 1213: 231-238.
8. DIXON RA, PAIVA NL (1995) Stress-induced phenylpropanoid metabolism. Plant Cell 7: 1085-1097.
9. EDITORIAL BOARD for FLORA of CHINA (1977) Flora of China. Science Press, Beijing, pp: 387.
10. FANG L, LIN NM, WU YJ (2010) Simultaneous determination of four active components in Spica Prunellae by HPLC. China J Chin Materia Med 35: 616-619.
11. FANG XY, YU MMS, YUEN WH, ZEE SY, CHANG RCC (2005) Immune modulatory effects of Prunella vulgaris L. Int J Mol Med 15: 1109-1116.
12. GAO WF, YUAN WJ (2009) HPLC determination of oleanolic acid and ursolic acid in different parts of Rabdosia eriocalyx (Dunn) Hara. Chin Pharm J Anal 29: 1947-1949.
13. GRASSMANN J, HIPPELI S, ELSTNER EF (2002) Plant's defence and its benefits for animals and medicine: role of phenolics and terpenoids in avoiding oxygen stress. Plant Physiol Biochem 40: 471-478.
14. GUO QS, ZHOU LJ, GONG WH, WU XS (2010) Effect of different water treatments on quality and yield of spadix in Prunlla vulgaris. China J Chin Materia Med 35: 1795-1798.
15. HE LJ, LIANG YZ, ZHAO CX (2007) GC/MS study on chemical constituents of essential oil of Lemiaceae plants. Acta Chim Sinica 65: 223-232.
16. HOLZMANNOVA V (1996) Rosmarinic acid and its biological activity. Chem Listy 90: 486-496.
17. JIANG XZ, WU YZ, ZHANG DR, LIU W (2009) Cultivated techniques of Prunella vulgaris under good agriculture practice. J Jiangxi Univ Tradit Chin Med 21: 79-82.
18. KIM SY, SHIN HY, LIM JP, CHAE BS, PARK JS, HONG SG, KIM MS, JO DG, PARK WH, SHIN TY (2007) Effects of Prunella vulgaris on mast cellmediated allergic reaction and inflammatory cytokine production. Exp Biol Med 232: 921-926.
19. LAMAISON JL, PETITJEAN-FREYTET C, CARNAT A (1991) Medicinal Laminaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv 66: 185-188.
20. LANGENHEIM JH (1994) Higher plant terpenoids: a phytocentric overview of their ecological roles. J Chem Ecol 20: 1223-1280.
21. LARANJINHA JAN, ALMEIDA LM, MADEIRA VMC (1994) Reactivity of dietary phenolic acids with peroxyl radicals: antioxidant activity upon low density lipoprotein peroxidation. Biochem Pharmacol 48: 487-494.
22. LENG GH (2011) Determination of oleanolic acid and ursolic acid in different parts of Mesona Chinensis Benth by RP-HPLC. Chin J Spectrosc Lab 28: 2111-2114.
23. LIAO L, LIU L, GUO QS, WANG ZY, CHEN YH (2010) Morphological and chemical variation of Prunella vulgaris populations from different locations in China. Chin Herb Med 2: 305-311.
24. LIU HX, SHI YH, WANG DX, YANG GL, YU AM, ZHANG HQ (2003) MECC determination of oleanolic acid and ursolic acid isomers in Ligustrum lucidum Ait. J Pharm Biomed Anal 32: 479-485.
25. LIU J (1995) Pharmacology of oleanolic acid and ursolic acid. J Ethnopharmacol 49: 57-68.
26. LIU P, YUAN BG, YIN DD, MIAN F (2010) Accumulation Laws of main medicinal ingredients in different part of Prunella vulgaris L. Acta Agri Boreali-Occidentalis Sin 19: 137-140.
27. LUCKNER M (1980) Expression and control of secondary metabolism. In: BELL EA, CHARLWOOD BV (eds) Secondary Plant Products. Heidelberg: Springer-Verlag. pp: 23-63.
28. LUO MH, ZHOU RB, TONG QZ, QU WH (2005) A Study on the optimum picking period for Prunella vugaris L. cultivated in a standardized way. J Hunan Univ Tradit Chin Med 25: 12-14.
29. MARKOVA H, SOUSEK J, ULRICHOVA J (1997) Prunella vulgaris L.-a rediscovered medical plant, Ceska Slov Farm 46: 58-63.
30. OSAKABE N, TAKANO H, SANBONGI C, YASUDA A, YANAGISAWA R, INOUE K, YOSHIKAWA T (2004) Anti-inflammatory and antiallergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism. BioFactors 21: 127-131.
31. OSAKABE N, YASUDA A, NATSUME M, SANBONGI C, KATO Y, OSAWA T, YOSHIKAWA T (2002) Rosmarinic acid a major polyphenolic component of Perilla frutescens, reduces lipopolysaccharide (LPS)-induced liver injury in D-galactosamine-sensitizied mice. Free Radic Biol Med 33: 798-806.
32. PINKAS M, TROTIN F, PENG M, TROCK M (1994) Use chemistry and pharmacology of the Chinese medicinal plants. Fitoterapia 55: 343-353.
33. PSOTOVA J, KOLAR M, SOUSEK J, ŠVAGERA Z, VICAR J, ULRICHOVA J (2003) Biological activities of Prunella vulgaris extract. Phytother Res 17: 1082-1087.
34. PSOTOVA J, SVOBODOVA A, KOLAROVA H, WALTEROVA D (2006) Photoprotective properties of Prunella vulgaris and rosmarinic acid on human keratinocytes. J Photochem Photobiol B: Biol 84: 167-174.
35. RYU SY, OAK MH, YOON SK, CHO DI, YOO GS, KIM TS, KIM KM (2000) Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris. Planta Med 66: 358-360.
36. SELLAMI IH, MAAMOURI E, CHAHED T, WANNES WA, KCHOUK ME, MARZOUK B (2009) Effect of growth stage on the content and composition of the essential oil and phenolic fraction of sweet marjoram (Origanum majorana L.). Ind Crops Prod 30: 395-402.
37. VERMA V, KASERA PK (2007) Variations in secondary metabolites in some arid zone medicinal plants in relation to season and plant growth. Indian J Plant Physiol 12: 203-206.
38. WANG HB, ZHANG ZY, SU ZW, LI CH (1994) Herbalogical Study on Common Selfheal (Prunella vulgaris). Chin Tradit Herbal Drugs 25: 213-214.
39. WANG YX, YIN JB, GUO QS, XIAO YH (2011) Dynamic change of active component content in different parts of Prunella vulgaris. China J Chin Materia Med 36: 741-745.
40. WANG ZJ, ZHAO YY, WANG B, AI TM, CHEN YY (2000) Depsides from Prunella vulgaris. Chin Chem Letters 11: 997-1000.
41. WU JF, LIU B, ZHU CC, LAI XP (2004) Determination of 2α-hydroxy-ursolic acid from Herba rabdosiae Serrae in various collecting periods. Chin Tradit Herbal Drugs 35: 81-83.
42. WU Z, GUO QS, WANG QY, ZHOU LJ, ZHANG ZY, ZHANG LX, HUANG T (2010) Effects of lead, copper and cadmium stresses on growth and inherent quality of Prunalla vulgaris. China J Chin Materia Med 35: 263-267.
43. XU HX, LEE SHS, LEE SF, WHITE RL, BLAY J (1999) Isolation and characterization of an anti-HSV polysaccharide from Prunella vulgaris. Antiviral Res 44: 43-54.
44. ZHANG GW, HE L, HU MM (2011) Optimized ultrasonic-assisted extraction of flavonoids from Prunella vulgaris L. and evaluation of antioxidant activities in vitro. Innov Food Sci Emerg 2: 18-25.
45. ZHANG LZ, QIN W, ZHANG XH (2007) Assay method for contents of caffeic acid and rosmarinic acid in the different parts of Prunella vulgaris L. Beijing Univ Trad Chin Med 30: 343-345.
46. ZHENG J, HE JG, JI BP, LI Y, ZHANG XF (2007) Antihyperglycemic activity of Prunella vulgaris L. in streptozotocin-induced diabetic mice. Asia Pac J Clin Nutr 16: 427-431.
47. ZOU SQ (2010) Determination of oleanolic acid and ursolic acid in the different parts of Lavandula angustifolia Mill. by HPLC-PAD. Chin Pharm J 45: 949-951.