Vaccination with enzymatically cleaved GPI-anchored proteins from schistosoma mansoni induces protection against challenge infection

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Martins, Vicente P ^a,b   Pinheiro, Carina S ^a,b   Figueiredo, Barbara C P ^a,b   Assis, Natan R G ^a,b   Morais, Suellen B ^a,b   Caliari, Marcelo V ^a   Azevedo, Vasco ^a   Castro Borges, William ^c   Wilson, R Alan ^d   Oliveira, Sergio C ^a,b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b National Institute of Science and Technology of Tropical Diseases INCT DT CNPq MCT   (Brazil)

^c FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^d UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLYCOSYLPHOSPHATIDYLINOSITOL; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 5; SCHISTOSOMA VACCINE; TUMOR NECROSIS FACTOR ALPHA; HELMINTH ANTIBODY; HELMINTH PROTEIN; PARASITE ANTIGEN; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CERCARIA; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNIZATION; INTERFERON PRODUCTION; LIVER; LIVER FIBROSIS; LIVER GRANULOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PURIFICATION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SPLEEN CELL; TH1 CELL; TH2 CELL; VACCINATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; IMMUNOLOGY;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; FEMALE; GLYCOSYLPHOSPHATIDYLINOSITOLS; HELMINTH PROTEINS; INTERFERON-GAMMA; INTERLEUKIN-5; MICE; MICE, INBRED C57BL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; TH1 CELLS; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA; VACCINATION; VACCINES;

EID: 84866078633     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/962538     Document Type: Article

References (39)

1. van der Werf M. J., de Vlas S. J., Brooker S., Looman C. W. N., Nagelkerke N. J. D., Habbema J. D. F., Engels D., Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Tropica 2003 86 2-3 125 139 2-s2.0-0037847426 10.1016/S0001-706X(03)00029-9 (Pubitemid 36561364)
2. Steinmann P., Keiser J., Bos R., Tanner M., Utzinger J., Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infectious Diseases 2006 6 7 411 425 2-s2.0-33745436655 10.1016/S1473-3099(06)70521-7 (Pubitemid 43949139)
3. Harder A., Chemotherapeutic approaches to trematodes (except schistosomes) and cestodes: current level of knowledge and outlook. Parasitology Research 2002 88 6 587 590 2-s2.0-0036022163 10.1007/s00436-001-0587-y (Pubitemid 34810727)
4. Bergquist N. R., Colley D. G., Schistosomiasis vaccines: research to development. Parasitology Today 1998 14 3 99 104 2-s2.0-0032030745 10.1016/S0169-4758(97)01207-6 (Pubitemid 28101506)
5. Bergquist N. R., Schistosomiasis: from risk assessment to control. Trends in Parasitology 2002 18 7 309 314 2-s2.0-0036630087 10.1016/S1471-4922(02) 02301-2 (Pubitemid 35257856)
6. Chitsulo L., Loverde P., Engels D., Schistosomiasis. Nature Reviews Microbiology 2004 2 1 12 13 2-s2.0-1842486669 10.1038/nrmicro801 (Pubitemid 39490043)
7. Hotez P. J., Bethony J. M., Diemert D. J., Pearson M., Loukas A., Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews Microbiology 2010 8 11 814 826 2-s2.0-77958082295 10.1038/nrmicro2438
8. Tran M. H., Pearson M. S., Bethony J. M., Smyth D. J., Jones M. K., Duke M., Don T. A., McManus D. P., Correa-Oliveira R., Loukas A., Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nature Medicine 2006 12 7 835 840 2-s2.0-33745907521 10.1038/nm1430 (Pubitemid 44050075)
9. Cardoso F. C., Macedo G. C., Gava E., Kitten G. T., Mati V. L., de Melo A. L., Caliari M. V., Almeida G. T., Venancio T. M., Verjovski-Almeida S., Oliveira S. C., Schistosoma mansoni tegument protein Sm29 is able to induce a Th1-type of immune response and protection against parasite infection. PLoS Neglected Tropical Diseases 2008 2 10, article e308 2-s2.0-56149122056 10.1371/journal.pntd.0000308
10. Jones M. K., Gobert G. N., Zhang L., Sunderland P., McManus D. P., The cytoskeleton and motor proteins of human schistosomes and their roles in surface maintenance and host-parasite interactions. BioEssays 2004 26 7 752 765 2-s2.0-3343027201 10.1002/bies.20058 (Pubitemid 38987609)
11. Van Hellemond J. J., Retra K., Brouwers J. F. H. M., van Balkom B. W. M., Yazdanbakhsh M., Shoemaker C. B., Tielens A. G. M., Functions of the tegument of schistosomes: clues from the proteome and lipidome. International Journal for Parasitology 2006 36 6 691 699 2-s2.0-33646780234 10.1016/j.ijpara.2006.01.007 (Pubitemid 43765725)
12. Castro-Borges W., Dowle A., Curwen R. S., Thomas-Oates J., Wilson R. A., Enzymatic shaving of the tegument surface of live schistosomes for proteomic analysis: a rational approach to select vaccine candidates. PLoS Neglected Tropical Diseases 2011 5 3, article e993 2-s2.0-79953770681 10.1371/journal. pntd.0000993
13. Castro-Borges W., Simpson D. M., Dowle A., Curwen R. S., Thomas-Oates J., Beynon R. J., Wilson R. A., Abundance of tegument surface proteins in the human blood fluke Schistosoma mansoni determined by QconCAT proteomics. Journal of Proteomics 2011 74 9 1519 1533 2-s2.0-79959797819 10.1016/j.jprot.2011.06.011
14. Paulick M. G., Bertozzi C. R., The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry 2008 47 27 6991 7000 2-s2.0-46849102138 10.1021/bi8006324 (Pubitemid 351956348)
15. Ferguson M. A. J., The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research. Journal of Cell Science 1999 112 17 2799 2809 2-s2.0-0032820595 (Pubitemid 29430025)
16. Eisenhaber B., Maurer-Stroh S., Novatchkova M., Schneider G., Eisenhaber F., Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins. BioEssays 2003 25 4 367 385 2-s2.0-0037387522 10.1002/bies.10254 (Pubitemid 36433183)
17. Tiede A., Bastisch I., Schubert J., Orlean P., Schmidt R. E., Biosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes. Biological Chemistry 1999 380 5 503 523 2-s2.0-0032996466 10.1515/BC.1999.066 (Pubitemid 29248439)
18. Nosjean O., Briolay A., Roux B., Mammalian GPI proteins: sorting, membrane residence and functions. Biochimica et Biophysica Acta 1997 1331 2 153 186 2-s2.0-0030885251 10.1016/S0304-4157(97)00005-1 (Pubitemid 27387442)
19. Teixeira de Melo T., Michel de Araujo J., Do Valle Durães F., Caliari M. V., Oliveira S. C., Coelho P. M. Z., Fonseca C. T., Immunization with newly transformed Schistosoma mansoni schistosomula tegument elicits tegument damage, reduction in egg and parasite burden. Parasite Immunology 2010 32 11-12 749 759 2-s2.0-78650507905 10.1111/j.1365-3024.2010.01244.x
20. Laemmli U. K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970 227 5259 680 685 2-s2.0-0014949207 10.1038/227680a0
21. Towbin H., Staehelin T., Gordon J., Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences of the United States of America 1979 76 9 4350 4354 2-s2.0-0009482260 (Pubitemid 9256559)
22. Fonseca C. T., Brito C. F. A., Alves J. B., Oliveira S. C., IL-12 enhances protective immunity in mice engendered by immunization with recombinant 14 kDa Schistosoma mansoni fatty acid-binding protein through an IFN- γ and TNF- α dependent pathway. Vaccine 2004 22 3-4 503 510 2-s2.0-0344234353 10.1016/j.vaccine.2003.07.010 (Pubitemid 37510282)
23. Pacífico L. G. G., Fonseca C. T., Chiari L., Oliveira S. C., Immunization with Schistosoma mansoni 22.6 kDa antigen induces partial protection against experimental infection in a recombinant protein form but not as DNA vaccine. Immunobiology 2006 211 1-2 97 104 2-s2.0-31444451162 10.1016/j.imbio.2005.06.004 (Pubitemid 43150111)
24. Farias L. P., Cardoso F. C., Miyasato P. A., Montoya B. O., Tararam C. A., Roffato H. K., Kawano T., Gazzinelli A., Correa-Oliveira R., Coulson P. S., Wilson R. A., Oliveira S. C., Leite L. C. C., Schistosoma mansoni stomatin like protein-2 is located in the tegument and induces partial protection against challenge infection. PLoS Neglected Tropical Diseases 2010 4 2, article e597 2-s2.0-77649209926 10.1371/journal.pntd.0000597
25. Ahmad G., Torben W., Zhang W., Wyatt M., Siddiqui A. A., Sm-p80-based DNA vaccine formulation induces potent protective immunity against Schistosoma mansoni: brief Definitive Report. Parasite Immunology 2009 31 3 156 161 2-s2.0-60349094458 10.1111/j.1365-3024.2008.01091.x
26. Nascimento E. J. M., Amorim R. V., Cavalcanti A., Alves V. F., Nakazawa M., Pereira V. R. A., Lucena-Silva N., Assessment of a DNA vaccine encoding an anchored- glycosylphosphatidylinositol tegumental antigen complexed to protamine sulphate on immunoprotection against murine schistosomiasis. Memorias do Instituto Oswaldo Cruz 2007 102 1 21 27 2-s2.0-33847167170 (Pubitemid 46280331)
27. Pearce E. J., Magee A. I., Smithers S. R., Simpson A. J. G., Sm25, a major schistosome tegumental glycoprotein, is dependent on palmitic acid for membrane attachment. The EMBO Journal 1991 10 10 2741 2746 2-s2.0-0025861153 (Pubitemid 21905290)
28. Petzke M. M., Suri P. K., Bungiro R., Goldberg M., Taylor S. F., Ranji S., Taylor H., McCray J. W., Knopf P. M., Schistosoma mansoni gene GP22 encodes the tegumental antigen Sm25: (1) Antibodies to a predicted B-cell epitope of Sm25 cross-react with other candidate vaccine worm antigens; (2) characterization of a recombinant product containing tandem-repeats of this peptide as a vaccine. Parasite Immunology 2000 22 8 381 395 2-s2.0-0033943067 10.1046/j.1365-3024.2000.00316.x (Pubitemid 30481029)
29. Pinheiro C. S., Martins V. P., Assis N. R., Figueiredo B. C., Morais S. B., Azevedo V., Oliveira S. C., Computational vaccinology: an important strategy to discover new potential S. mansoni vaccine candidates. Journal of Biomedicine and Biotechnology 2011 2011 9 503068 10.1155/2011/503068
30. Minard P., Dean D. A., Jacobson R. H., Vannier W. E., Murrell K. D., Immunization of mice with cobalt-60 irradiated Schistosoma mansoni cercariae. American Journal of Tropical Medicine and Hygiene 1978 27 1, part 1 76 86 2-s2.0-0017837224 (Pubitemid 8269673)
31. Nascimento E. J. M., Amorim R. V., Cavalcanti A., Alves V. F., Nakazawa M., Pereira V. R. A., Lucena-Silva N., Assessment of a DNA vaccine encoding an anchored- glycosylphosphatidylinositol tegumental antigen complexed to protamine sulphate on immunoprotection against murine schistosomiasis. Memorias do Instituto Oswaldo Cruz 2007 102 1 21 27 2-s2.0-33847167170 (Pubitemid 46280331)
32. Wilson R. A., Coulson P. S., Betts C., Dowling M. A., Smythies L. E., Impaired immunity and altered pulmonary responses in mice with a disrupted interferon- γ receptor gene exposed to the irradiated Schistosoma mansoni vaccine. Immunology 1996 87 2 275 282 2-s2.0-0030059935 (Pubitemid 26057921)
33. Cheever A. W., Poindexter R. W., Wynn T. A., Egg laying is delayed but worm fecundity is normal in SCID mice infected with Schistosoma japonicum and S. mansoni with or without recombinant tumor necrosis factor alpha treatment. Infection and Immunity 1999 67 5 2201 2208 2-s2.0-0032954437 (Pubitemid 29200473)
34. Pearce E. J., MacDonald A. S., The immunobiology of schistosomiasis. Nature Reviews Immunology 2002 2 7 499 511 2-s2.0-0036636093 (Pubitemid 37328741)
35. Garcia T. C. M., Fonseca C. T., Pacifico L. G. G., Durães F. D. V., Marinho F. A. V., Penido M. L. O., Caliari M. V., de Melo A. L., Pinto H. A., Barsante M. M., Cunha-Neto E., Oliveira S. C., Peptides containing T cell epitopes, derived from Sm14, but not from paramyosin, induce a Th1 type of immune response, reduction in liver pathology and partial protection against Schistosoma mansoni infection in mice. Acta Tropica 2008 106 3 162 167 2-s2.0-43849112632 10.1016/j.actatropica.2008.03.003
36. Cook R. M., Carvalho-Queiroz C., Wilding G., LoVerde P. T., Nucleic acid vaccination with Schistosoma mansoni antioxidant enzyme cytosolic superoxide dismutase and the structural protein filamin confers protection against the adult worm stage. Infection and Immunity 2004 72 10 6112 6124 2-s2.0-4644286484 10.1128/IAI.72.10.6112-6124.2004 (Pubitemid 39303727)
37. Siles-Lucas M., Uribe N., López-Abán J., Vicente B., Orfao A., Nogal-Ruiz J. J., Feliciano A. S., Muro A., The Schistosoma bovis Sb14-3-3 ζ recombinant protein cross-protects against Schistosoma mansoni in BALB/c mice. Vaccine 2007 25 41 7217 7223 2-s2.0-34648843570 10.1016/j.vaccine.2007.07. 021 (Pubitemid 47464668)
38. Sadler C. H., Rutitzky L. I., Stadecker M. J., Wilson R. A., IL-10 is crucial for the transition from acute to chronic disease state during infection of mice with Schistosoma mansoni. European Journal of Immunology 2003 33 4 880 888 2-s2.0-0038476617 10.1002/eji.200323501 (Pubitemid 36546675)
39. Hogg K. G., Kumkate S., Mountford A. P., IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine. International Immunology 2003 15 12 1451 1459 2-s2.0-0348038752 10.1093/intimm/dxg142 (Pubitemid 37536746)