MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy

Gene Therapy

Volumn 19, Issue 9, 2012, Pages 915-924

  Lachmann, N ^a   Jagielska, J ^a   Heckl, D ^a   Brennig, S ^a   Pfaff, N ^a   Maetzig, T ^a   Modlich, U ^a   Cantz, T ^a,b   Gentner, B ^b   Schambach, A ^a   Moritz, T ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

Author keywords

hematopoiesis; microRNA; transgene regulation

Indexed keywords

LENTIVIRUS VECTOR; MICRORNA; MICRORNA 150; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; FEMALE; GENE CONTROL; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

ANIMALS; B-LYMPHOCYTES; CELL LINE; DOWN-REGULATION; FEMALE; GENE TARGETING; GENETIC VECTORS; HEMATOPOIESIS; MALE; MICE; MICE, NUDE; MICRORNAS; T-LYMPHOCYTES; TRANSGENES;

MURINAE;

EID: 84866074195     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.148     Document Type: Article

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