Serum brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 levels in dementia

Acta Neurologica Belgica

Volumn 112, Issue 3, 2012, Pages 255-260

  Konukoglu, Dildar ^a,b   Andican, Gülnur ^b   Fırtına, Sinem ^b   Erkol, Gökhan ^b   Kurt, Asuman ^b  

^a Atakoy Hospital   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Alzheimer's disease; Brain derived neurotrophic factor; Dementia; Nerve growth factor; Neurotrophin 3; Neurotropic factor

Indexed keywords

ALBUMIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLINESTERASE INHIBITOR; CREATININE; CYANOCOBALAMIN; FOLIC ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NERVE GROWTH FACTOR; NEUROTROPHIN 3; PROTEIN; THYROID HORMONE; TRIACYLGLYCEROL; UREA;

AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; MULTIINFARCT DEMENTIA; NEUROLOGIC EXAMINATION;

EID: 84866073405     PISSN: 03009009     EISSN: 22402993     Source Type: Journal    
DOI: 10.1007/s13760-012-0101-6     Document Type: Article

References (38)

1. Grossman H, Bergmann C, Parker S (2006) Dementia: a brief review. Mt Sinai J Med 73(7): 985-992.
2. Maccioni RB, Muñoz JP, Barbeito L (2001) The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch Med Res 32: 367-371.
3. Good PF, Werner P, Hsu A, Olanow CW, Perl DP (1996) Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol 149: 21-28.
4. Perry G, Taddeo MA, Nunomura A, Zhu X, Zenteno-Savin T et al (2002) Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comp Biochem Physiol 133: 507-513.
5. Dugué M, Neugroschl J, Sewell M, Marin D (2003) Review of dementia. Mt Sinai J Med 70: 45-53.
6. Mattson MP, Chan SL, Duan W (2002) Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior. Physiol Rev 82: 637-672.
7. Schulte-Herbrüggen O, Jockers-Scherübl MC, Hellweg R (2008) Neurotrophins: from pathophysiology to treatment in Alzheimer's disease. Curr Alzheimer Res 5: 38-44.
8. McKhann G, Drachman D, Folstein M, Katzman R, Price D et al (1984) Clinical diagnosis of Alzheimer's disease-report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34: 939-944.
9. Roman GC, Tatemichi TK, Erkinjuntti T, Cummings JL, Masdeu JC et al (1993) Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43: 250-260.
10. Folstein MF, Folstein SE, McHugh PR (1975) "Mini-Mental-State". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198.
11. Alderson RF, Alterman AL, Barde YA, Lindsay RM (1991) Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurones in culture. Neuron 5: 297-306.
12. Schindowski K, Belarbi K, Buée L (2008) Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes Brain Behav 7: 43-56.
13. Royo NC, Conte V, Saatman KE, Shimizu S, Belfield CM et al (2006) Hippocampal vulnerability following traumatic brain injury: a potential role for neurotrophin-4/5 in pyramidal cell neuroprotection. Eur J Neurosci 23(5): 1089-1102.
14. Karege F, Schwald M, Cisse M (2002) Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 16; 328(3): 261-264.
15. Durany N, Michel T, Kurt J, Cruz-Sánchez FF, Cervás-Navarro J et al (2000) Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains. Int J Dev Neurosci 18: 807-813.
16. Hock C, Heese K, Hulette C, Rosenberg C, Otten U (2000) Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol 57: 846-851.
17. Ziegenhorn AA, Schulte-Herbrüggen O, Danker-Hopfe H, Malbranc M, Hartung HD et al (2007) Serum neurotrophins-a study on the time course and influencing factors in a large old age sample. Neurobiol Aging 28: 1436-1445.
18. Yasutake C, Kuroda K, Yanagawa T, Okamura T, Yoneda H, Serum BDNF (2006) TNF-alpha and IL-1beta levels in dementia patients: comparison between Alzheimer's disease and vascular dementia. Eur Arch Psychiatry Clin Neurosci 256: 402-406.
19. Laske C, Stransky E, Leyhe T, Eschweiler GW, Wittorf A et al (2006) Stage-dependent BDNF serum concentrations in Alzheimer's disease. J Neural Transm 113: 1217-1224.
20. Laske C, Stransky E, Leyhe T, Eschweiler GW, Maetzler W et al (2007) BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls. J Psychiatr Res 41: 387-394.
21. Miyake K, Yamamoto W, Tadokoro M (2002) Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia. Brain Res 935: 24-31.
22. Lindvall O, Ernfors P, Bengzon J (1992) Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc Natl Acad Sci USA 89: 648-652.
23. Nakahashi T, Fujimura H, Altar CA, Li J, Kambayashi J et al (2000) Vascular endothelial cells synthesize and secrete brain-derived neurotrophic factor. FEBS Lett 470: 113-117.
24. Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C et al (2005) The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging 26: 115-123.
25. Wang J, Zhang HY, Tang XC (2009) Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment. Acta Pharmacol Sin 30: 879-888.
26. Leyhe T, Stransky E, Eschweiler GW, Buchkremer G, Laske C (2008) Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease. Eur Arch Psychiatry Clin Neurosci 258: 24-28.
27. Darreh-Shori T, Soininen H (2010) Effects of cholinesterase inhibitors on the activities and protein levels of cholinesterases in the cerebrospinal fluid of patients with Alzheimer's disease: a review of recent clinical studies. Curr Alzheimer Res 7(1): 67-73.
28. Winter B, Breitenstein C, Mooren FC, Voelker K, Fobker M et al (2007) High impact running improves learning. Neurobiol Learn Mem 87: 597-609.
29. Lee HY, Kim YK (2008) Plasma brain-derived neurotrophic factor as a peripheral marker for the action mechanism of antidepressants. Neuropsychobiology 57: 194-199.
30. Lad SP, Neet KE, Mufson EJ (2003) Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Curr Drug Targets CNS Neurol Disord 2: 315-334.
31. Murase K, Nabeshima T, Robitaille Y, Quirion R, Ogawa M, Hayashi K (1993) NGF level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease. Biochem Biophys Res Commun 193: 198-203.
32. Schaub RT, Anders D, Golz G, Göhringer K, Hellweg R (2002) Serum nerve growth factor concentration and its role in the preclinical stage of dementia. Am J Psychiatry 159: 1227-1229.
33. Narisawa-Saito M, Nawa H (1996) Differential regulation of hippocampal neurotrophins during aging in rats. J Neurochem 67: 1124-1131.
34. Chao MV, Rajagopal R, Lee FS (2006) Neurotrophin signalling in health and disease. Clin Sci (Lond) 110: 167-173.
35. Pan W, Banks WA, Kastin AJ (1998) Permeability of the blood-brain barrier to neurotrophins. Brain Res 788: 87-94.
36. Walz JC, Andreazza AC, Frey BN, Cacilhas AA, Ceresér KM et al (2007) Serum neurotrophin-3 is increased during manic and depressive episodes in bipolar disorder. Neurosci Lett 19: 87-89.
37. Nemoto K, Ohnishi T, Mori T et al (2006) The Val66Met polymorphism of the brain-derived neurotrophic factor gene affects age-related brain morphology. Neurosci Lett 397: 25-29.
38. Colcombe SJ, Kramer AF, McAuley E, Erickson KI, Scalf P (2004) Neurocognitive aging and cardiovascular fitness: recent findings and future directions. J Mol Neurosci 24: 9-14.