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Volumn 287, Issue 37, 2012, Pages 31462-31470

The adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; CELL LINES; CELL MIGRATION; CELL SHAPES; CELLULAR TRANSFORMATION; CERVICAL CARCINOMA; CO-EXPRESSION; GTPASE-ACTIVATING PROTEIN; GTPASES; HELA CELL; IN-VITRO; MULTIFUNCTIONAL PROTEIN; ONCOGENIC TRANSFORMATION; PAXILLIN; SIGNALING PROTEINS; SOFT AGAR; TUMOR SAMPLES; UP-REGULATION;

EID: 84866054635     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.353615     Document Type: Article
Times cited : (15)

References (40)
  • 1
    • 0033529562 scopus 로고    scopus 로고
    • A tyrosine-phosphorylated protein that binds to an important regulatory region on the Cool family of p21-activated kinase-binding proteins
    • Bagrodia, S., Bailey, D., Lenard, Z., Hart, M., Guan, J. L., Premont, R. T., Taylor, S. J., and Cerione, R. A. (1999) A tyrosine-phosphorylated protein that binds to an important regulatory region on the Cool family of p21-activated kinase-binding proteins. J. Biol. Chem. 274, 22393-22400
    • (1999) J. Biol. Chem. , vol.274 , pp. 22393-22400
    • Bagrodia, S.1    Bailey, D.2    Lenard, Z.3    Hart, M.4    Guan, J.L.5    Premont, R.T.6    Taylor, S.J.7    Cerione, R.A.8
  • 2
    • 33646705915 scopus 로고    scopus 로고
    • The multifunctional Git family of proteins
    • Hoefen, R. J., and Berk, B. C. (2006) The multifunctional Git family of proteins. J. Cell Sci. 119, 1469-1475
    • (2006) J. Cell Sci. , vol.119 , pp. 1469-1475
    • Hoefen, R.J.1    Berk, B.C.2
  • 3
    • 35348913710 scopus 로고    scopus 로고
    • Arf GAPs and their interacting proteins
    • Inoue, H., and Randazzo, P. A. (2007) Arf GAPs and their interacting proteins. Traffic 8, 1465-1475
    • (2007) Traffic , vol.8 , pp. 1465-1475
    • Inoue, H.1    Randazzo, P.A.2
  • 4
    • 0035999990 scopus 로고    scopus 로고
    • Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involve a multistep activation pathway
    • Brown, M. C., West, K. A., and Turner, C. E. (2002) Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involve a multistep activation pathway. Mol. Biol. Cell 13, 1550-1565
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1550-1565
    • Brown, M.C.1    West, K.A.2    Turner, C.E.3
  • 5
    • 26944442735 scopus 로고    scopus 로고
    • The Git-associated kinase Pak targets to the centrosome and regulates Aurora-A
    • Zhao, Z. S., Lim, J. P., Ng, Y. W., Lim, L., and Manser, E. (2005) The Git-associated kinase Pak targets to the centrosome and regulates Aurora-A. Mol. Cell 20, 237-249
    • (2005) Mol. Cell , vol.20 , pp. 237-249
    • Zhao, Z.S.1    Lim, J.P.2    Ng, Y.W.3    Lim, L.4    Manser, E.5
  • 10
    • 0035833251 scopus 로고    scopus 로고
    • The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL)
    • West, K. A., Zhang, H., Brown, M. C., Nikolopoulos, S. N., Riedy, M. C., Horwitz, A. F., and Turner, C. E. (2001) The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). J. Cell Biol. 154, 161-176
    • (2001) J. Cell Biol. , vol.154 , pp. 161-176
    • West, K.A.1    Zhang, H.2    Brown, M.C.3    Nikolopoulos, S.N.4    Riedy, M.C.5    Horwitz, A.F.6    Turner, C.E.7
  • 11
    • 37549027648 scopus 로고    scopus 로고
    • Activity-dependent synaptogenesis: Regulation by a CaM-kinase kinase/CaM-kinase I/βPix signaling complex
    • Saneyoshi, T., Wayman, G., Fortin, D., Davare, M., Hoshi, N., Nozaki, N., Natsume, T., and Soderling, T. R. (2008) Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/βPix signaling complex. Neuron 57, 94-107
    • (2008) Neuron , vol.57 , pp. 94-107
    • Saneyoshi, T.1    Wayman, G.2    Fortin, D.3    Davare, M.4    Hoshi, N.5    Nozaki, N.6    Natsume, T.7    Soderling, T.R.8
  • 12
    • 0037437147 scopus 로고    scopus 로고
    • Synapse formation is regulated by the signaling adaptor Git1
    • Zhang, H., Webb, D. J., Asmussen, H., and Horwitz, A. F. (2003) Synapse formation is regulated by the signaling adaptor Git1. J. Cell Biol. 161, 131-142
    • (2003) J. Cell Biol. , vol.161 , pp. 131-142
    • Zhang, H.1    Webb, D.J.2    Asmussen, H.3    Horwitz, A.F.4
  • 14
    • 20644447796 scopus 로고    scopus 로고
    • Dynamic recruitment of Pak1 to the immunological synapse is mediated by Pix independently of SLP-76 and Vav1
    • Phee, H., Abraham, R. T., and Weiss, A. (2005) Dynamic recruitment of Pak1 to the immunological synapse is mediated by Pix independently of SLP-76 and Vav1. Nat. Immunol. 6, 608-617
    • (2005) Nat. Immunol. , vol.6 , pp. 608-617
    • Phee, H.1    Abraham, R.T.2    Weiss, A.3
  • 17
    • 41549102357 scopus 로고    scopus 로고
    • The Pix-Git complex: A G-proteinsignaling cassette in control of cell shape
    • Frank, S. R., and Hansen, S. H. (2008) The Pix-Git complex: a G-proteinsignaling cassette in control of cell shape. Semin. Cell Dev. Biol. 19, 234-244
    • (2008) Semin. Cell Dev. Biol. , vol.19 , pp. 234-244
    • Frank, S.R.1    Hansen, S.H.2
  • 18
    • 0033843129 scopus 로고    scopus 로고
    • Coupling of Pakinteracting exchange factor Pix to Git1 promotes focal complex disassembly
    • Zhao, Z. S., Manser, E., Loo, T. H., and Lim, L. (2000) Coupling of Pakinteracting exchange factor Pix to Git1 promotes focal complex disassembly. Mol. Cell. Biol. 20, 6354-6363
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6354-6363
    • Zhao, Z.S.1    Manser, E.2    Loo, T.H.3    Lim, L.4
  • 19
    • 73949141711 scopus 로고    scopus 로고
    • Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration
    • Yu, J. A., Deakin, N. O., and Turner, C. E. (2009) Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration. Mol. Biol. Cell 20, 4706-4719
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4706-4719
    • Yu, J.A.1    Deakin, N.O.2    Turner, C.E.3
  • 20
    • 77953313163 scopus 로고    scopus 로고
    • Phosphorylation of the Cool-1/β-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells
    • Feng, Q., Baird, D., Yoo, S., Antonyak, M., and Cerione, R. A. (2010) Phosphorylation of the Cool-1/β-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells. J. Biol. Chem. 285, 18806-18816
    • (2010) J. Biol. Chem. , vol.285 , pp. 18806-18816
    • Feng, Q.1    Baird, D.2    Yoo, S.3    Antonyak, M.4    Cerione, R.A.5
  • 21
    • 0346095319 scopus 로고    scopus 로고
    • Git1 functions as a scaffold for MEK1-extracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor
    • Yin, G., Haendeler, J., Yan, C., and Berk, B. C. (2004) Git1 functions as a scaffold for MEK1-extracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor. Mol. Cell. Biol. 24, 875-885
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 875-885
    • Yin, G.1    Haendeler, J.2    Yan, C.3    Berk, B.C.4
  • 22
    • 23044477857 scopus 로고    scopus 로고
    • Git1 is a scaffold for ERK1/2 activation in focal adhesions
    • Yin, G., Zheng, Q., Yan, C., and Berk, B. C. (2005) Git1 is a scaffold for ERK1/2 activation in focal adhesions. J. Biol. Chem. 280, 27705-27712
    • (2005) J. Biol. Chem. , vol.280 , pp. 27705-27712
    • Yin, G.1    Zheng, Q.2    Yan, C.3    Berk, B.C.4
  • 24
    • 1942518365 scopus 로고    scopus 로고
    • Git1 activates p21-activated kinase through a mechanism independent of p21 binding
    • Loo, T. H., Ng, Y. W., Lim, L., and Manser, E. (2004) Git1 activates p21-activated kinase through a mechanism independent of p21 binding. Mol. Cell. Biol. 24, 3849-3859
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 3849-3859
    • Loo, T.H.1    Ng, Y.W.2    Lim, L.3    Manser, E.4
  • 26
    • 0033573126 scopus 로고    scopus 로고
    • Crystal structure of the Arf-GAP domain and ankyrin repeats of PYK2-associated protein β
    • Mandiyan, V., Andreev, J., Schlessinger, J., and Hubbard, S. R. (1999) Crystal structure of the Arf-GAP domain and ankyrin repeats of PYK2-associated protein β. EMBO J. 18, 6890-6898
    • (1999) EMBO J. , vol.18 , pp. 6890-6898
    • Mandiyan, V.1    Andreev, J.2    Schlessinger, J.3    Hubbard, S.R.4
  • 27
    • 0027724473 scopus 로고
    • Hydrolysis of bound GTP by Arf protein triggers uncoating of Golgi-derived COP-coated vesicles
    • Tanigawa, G., Orci, L., Amherdt, M., Ravazzola, M., Helms, J. B., and Rothman, J. E. (1993) Hydrolysis of bound GTP by Arf protein triggers uncoating of Golgi-derived COP-coated vesicles. J. Cell Biol. 123, 1365-1371
    • (1993) J. Cell Biol. , vol.123 , pp. 1365-1371
    • Tanigawa, G.1    Orci, L.2    Amherdt, M.3    Ravazzola, M.4    Helms, J.B.5    Rothman, J.E.6
  • 28
    • 0037174805 scopus 로고    scopus 로고
    • Characterization of a fast cycling ADP-ribosylation factor 6 mutant
    • Santy, L. C. (2002) Characterization of a fast cycling ADP-ribosylation factor 6 mutant. J. Biol. Chem. 277, 40185-40188
    • (2002) J. Biol. Chem. , vol.277 , pp. 40185-40188
    • Santy, L.C.1
  • 29
    • 0031260578 scopus 로고    scopus 로고
    • A novel Cdc42Hs mutant induces cellular transformation
    • Lin, R., Bagrodia, S., Cerione, R., and Manor, D. (1997) A novel Cdc42Hs mutant induces cellular transformation. Curr. Biol. 7, 794-797
    • (1997) Curr. Biol. , vol.7 , pp. 794-797
    • Lin, R.1    Bagrodia, S.2    Cerione, R.3    Manor, D.4
  • 30
    • 0028951905 scopus 로고
    • Overexpression of wild-type and mutant Arf1 and Arf6: Distinct perturbations of nonoverlapping membrane compartments
    • Peters, P. J., Hsu, V. W., Ooi, C. E., Finazzi, D., Teal, S. B., Oorschot, V., Donaldson, J. G., and Klausner, R. D. (1995) Overexpression of wild-type and mutant Arf1 and Arf6: distinct perturbations of nonoverlapping membrane compartments. J. Cell Biol. 128, 1003-1017
    • (1995) J. Cell Biol. , vol.128 , pp. 1003-1017
    • Peters, P.J.1    Hsu, V.W.2    Ooi, C.E.3    Finazzi, D.4    Teal, S.B.5    Oorschot, V.6    Donaldson, J.G.7    Klausner, R.D.8
  • 31
    • 0141426629 scopus 로고    scopus 로고
    • Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation
    • Wu, W. J., Tu, S., and Cerione, R. A. (2003) Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell 114, 715-725
    • (2003) Cell , vol.114 , pp. 715-725
    • Wu, W.J.1    Tu, S.2    Cerione, R.A.3
  • 32
    • 33748136028 scopus 로고    scopus 로고
    • Cool-1 functions as an essential regulatory node for EGF receptorand Src-mediated cell growth
    • Feng, Q., Baird, D., Peng, X., Wang, J., Ly, T., Guan, J. L., and Cerione, R. A. (2006) Cool-1 functions as an essential regulatory node for EGF receptorand Src-mediated cell growth. Nat. Cell Biol. 8, 945-956
    • (2006) Nat. Cell Biol. , vol.8 , pp. 945-956
    • Feng, Q.1    Baird, D.2    Peng, X.3    Wang, J.4    Ly, T.5    Guan, J.L.6    Cerione, R.A.7
  • 33
    • 0037108090 scopus 로고    scopus 로고
    • Antiapoptotic Cdc42 mutants are potent activators of cellular transformation
    • Tu, S. S., Wu, W. J., Yang, W., Nolbant, P., Hahn, K., and Cerione, R. A. (2002) Antiapoptotic Cdc42 mutants are potent activators of cellular transformation. Biochemistry 41, 12350-12358
    • (2002) Biochemistry , vol.41 , pp. 12350-12358
    • Tu, S.S.1    Wu, W.J.2    Yang, W.3    Nolbant, P.4    Hahn, K.5    Cerione, R.A.6
  • 34
    • 0034607876 scopus 로고    scopus 로고
    • Git proteins, a novel family of phosphatidylinositol 3,4,5-trisphosphate- stimulated GTPase-activating proteins for Arf6
    • Vitale, N., Patton, W. A., Moss, J., Vaughan, M., Lefkowitz, R. J., and Premont, R. T. (2000) Git proteins, a novel family of phosphatidylinositol 3,4,5-trisphosphate-stimulated GTPase-activating proteins for Arf6. J. Biol. Chem. 275, 13901-13906
    • (2000) J. Biol. Chem. , vol.275 , pp. 13901-13906
    • Vitale, N.1    Patton, W.A.2    Moss, J.3    Vaughan, M.4    Lefkowitz, R.J.5    Premont, R.T.6
  • 35
    • 0035173058 scopus 로고    scopus 로고
    • An ADP-ribosylation factor GTPase-activating protein Git2-short/ KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organization
    • Mazaki, Y., Hashimoto, S., Okawa, K., Tsubouchi, A., Nakamura, K., Yagi, R., Yano, H., Kondo, A., Iwamatsu, A., Mizoguchi, A., and Sabe, H. (2001) An ADP-ribosylation factor GTPase-activating protein Git2-short/ KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organization. Mol. Biol. Cell 12, 645-662
    • (2001) Mol. Biol. Cell , vol.12 , pp. 645-662
    • Mazaki, Y.1    Hashimoto, S.2    Okawa, K.3    Tsubouchi, A.4    Nakamura, K.5    Yagi, R.6    Yano, H.7    Kondo, A.8    Iwamatsu, A.9    Mizoguchi, A.10    Sabe, H.11
  • 36
    • 30544436453 scopus 로고    scopus 로고
    • In vitro assays of Arf1 interaction with GGA proteins
    • Yoon, H. Y., Bonifacino, J. S., and Randazzo, P. A. (2005) In vitro assays of Arf1 interaction with GGA proteins. Methods Enzymol. 404, 316-332
    • (2005) Methods Enzymol. , vol.404 , pp. 316-332
    • Yoon, H.Y.1    Bonifacino, J.S.2    Randazzo, P.A.3
  • 37
    • 77956555910 scopus 로고    scopus 로고
    • Paxillin regulates androgen- and epidermal growth factorinduced MAPK signaling and cell proliferation in prostate cancer cells
    • Sen, A., O'Malley, K., Wang, Z., Raj, G. V., Defranco, D. B., and Hammes, S. R. (2010) Paxillin regulates androgen- and epidermal growth factorinduced MAPK signaling and cell proliferation in prostate cancer cells. J. Biol. Chem. 285, 28787-28795
    • (2010) J. Biol. Chem. , vol.285 , pp. 28787-28795
    • Sen, A.1    O'Malley, K.2    Wang, Z.3    Raj, G.V.4    Defranco, D.B.5    Hammes, S.R.6
  • 38
    • 80055066706 scopus 로고    scopus 로고
    • Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by Ras
    • Wade, R., Brimer, N., Lyons, C., and Vande Pol, S. (2011) Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by Ras. J. Biol. Chem. 286, 37932-37944
    • (2011) J. Biol. Chem. , vol.286 , pp. 37932-37944
    • Wade, R.1    Brimer, N.2    Lyons, C.3    Vande Pol, S.4
  • 40
    • 78751701823 scopus 로고    scopus 로고
    • Models for the functions of Arf GAPs
    • East, M. P., and Kahn, R. A. (2011) Models for the functions of Arf GAPs. Semin. Cell Dev. Biol. 22, 3-9
    • (2011) Semin. Cell Dev. Biol. , vol.22 , pp. 3-9
    • East, M.P.1    Kahn, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.