Establishing a murine model of the hematopoietic syndrome of the acute radiation syndrome

Health Physics

Volumn 103, Issue 4, 2012, Pages 343-355

  Plett, P Artur ^a   Sampson, Carol H ^a   Chua, Hui Lin ^a   Joshi, Mandar ^a   Booth, Catherine ^b   Gough, Alec ^c   Johnson, Cynthia S ^a   Katz, Barry P ^a   Farese, Ann M ^d   Parker, Jeffrey ^d   MacVittie, Thomas J ^d   Orschell, Christie M ^a  

^a INDIANA UNIVERSITY   (United States)

^b Epistem Ltd   (United Kingdom)

^c Awg Pathology   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

blood mice; Dose assessment; modeling; radiation dose

Indexed keywords

ACUTE RADIATION SYNDROME; ANIMAL; ARTICLE; C57BL MOUSE; CELL SURVIVAL; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; LD 50; MALE; MOUSE; PATHOPHYSIOLOGY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION RESPONSE; SURVIVAL; SURVIVAL RATE; WHOLE BODY RADIATION;

ACUTE RADIATION SYNDROME; ANIMALS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; LETHAL DOSE 50; MALE; MICE; MICE, INBRED C57BL; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; SURVIVAL ANALYSIS; SURVIVAL RATE; WHOLE-BODY IRRADIATION;

ANIMALIA; MURINAE; MUS;

EID: 84866030616     PISSN: 00179078     EISSN: None     Source Type: Journal    
DOI: 10.1097/HP.0b013e3182667309     Document Type: Article

References (52)

1. Anno GH, Young RW, Bloom RM, Mercier JR. Dose response relationships for acute ionizing-radiation lethality. Health Phys 84:565-575; 2003.
2. Baverstock K, Ash P. A review of radiation accidents involving whole body exposure and the relevance to the LD50/60for man. Br J Radiol 56:837; 1983.
3. Bishop MR, Tarantolo SR, Geller RB, Lynch JC, Bierman PJ, Pavletic ZS, Vose JM, Kruse S, Dix SP, Morris ME, Armitage JO, Kessinger A. A randomized, double-blind trial of filgrastim (granulocyte colony-stimulating factor) versus placebo following allogeneic blood stem cell transplantation. Blood 96:80-85; 2000.
4. Booth C, Tudor G, Tudor J, Katz BP, MacVittie TJ. Acute gastrointestinal syndrome in high-dose irradiation mice. Health Phys 103(4):383-399; 2012.
5. Brook I, Elliott TB. Quinolone therapy in the prevention of mortality after irradiation. Radiat Res 128:100-103; 1991.
6. Brook I, Ledney GD. Ofloxacin and penicillin G combination therapy in prevention of bacterial translocation and animal mortality after irradiation. 35:1685-1687; 1991.
7. Brook I, Elliott TB, Ledney GD. Quinolone therapy of Klebsiella pneumoniae sepsis following irradiation: comparison of pefloxacin, ciprofloxacin, and ofloxacin. Radiat Res 122: 215-217; 1990.
8. Brook I, Germana A, Giraldo DE, Camp-Hyde TD, Bolduc DL, Foriska MA, Elliott TB, Thakar JH, Shoemaker MO, Jackson WE, Ledney GD. Clindamycin and quinolone therapy for Bacillus anthracis Sterne infection in 60Co-gamma-photonirradiated and sham-irradiated mice. J Antimicrob Chemother 56:1074-1080; 2005.
9. Casarett A. Radiation biology. Englewood, NJ: Prentice-Hall Inc; 1968.
10. Cerveny T, MacVittie T, Young R. Acute radiation syndrome in humans. Vol 2. Falls Church, VA: TTM Publisher; 1989.
11. Chua HL, Plett A, Sampson CH, Joshi J, Tabbey R, Katz B, MacVitte TJ, Orschell CM. Long-term hematopoietic stem cell damage in a murine model of the mematopoietic syndrome of the acute radiation syndrome. Health Phys 103(4):356-366; 2012.
12. Crawford L. New drug and biological drug products; evidence needed to demonstrate effectiveness of new drugs when human efficacy studies are not ethical or feasible. 21 CFR parts 314 and 601, FDA, HHS; ACTION: Final Rule: 37988-37998; 2002.
13. D'Antonio D, Piccolomini R, Iacone A, Fioritoni G, Parruti G, Betti S, Quaglietta AM, Accorsi P, Dell'Isola M, Favalli C. Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies. J Antimicrob Chemother 33:837-844; 1994.
14. Dainiak N. Hematologic consequences of exposure to ionizing radiation. Exp Hematol 30:513; 2002.
15. Dainiak N, Waselenko JK, Armitage JO, MacVittie TJ, Farese AM. The hematologist and radiation casualties. Hematol 473-496; 2003.
16. Farese AM, Hunt P, Grab LB, MacVittie TJ. Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia. J Clin Invest 97:2145-2151; 1996.
17. Farese AM, Cohen MV, Katz BP, Smith CP, Jackson III W, Cohen DM, MacVittie TJ. A nonhuman primate model of the hematopoietic acute radiation syndrome plus medical management. Health Phys 103(4):367-382; 2012.
18. Grahn D. Acute radiation response of mice from a cross between radiosensitive and radioresistant strains. Genetics 43: 835-843; 1958.
19. Grahn D, Hamilton K. Genetic variation in the acute lethal response of four inbred mouse strains to whole body x-irradiation. Genetics 42:189-198; 1957.
20. Haus E. Chronobiology of the mammalian response to ionizing radiation. Potential applications in oncology. Chronobiol Int 19:77-100; 2002.
21. Haus E, Halberg F, Loken MK, Kim YS. Circadian rhythmometry of mammalian radiosensitivity. New York: Academic Press; 1974.
22. Hellwig G, Rosenkranz J. Uber Circadiane Schwankungen der Strahlensensibilität von Ratten. Strahlentherapie 135: 220-222; 1968 (in German).
23. Hori S, Kizu J, Kawamura M. Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice. J Infection Chemotherapy 12:109-111; 2006.
24. Kohn H, Kallman K. The influence of strain on acute x-ray lethality in the mouse. I. LD50 and death rate studies. Radiat Res 5:309-317; 1956.
25. Lord BI, Woolford LB, Molineux G. Kinetics of neutrophil production in normal and neutropenic animals during the response to filgrastim (r-metHu G-CSF) or filgrastim SD/01 (PEG-rmetHu G-CSF). Clinical Cancer Res 7:2085-2090; 2001.
26. Lushbaugh C. Reflections on some recent progress in human radiobiology. Advances in Radiat Biol 277; 1969.
27. MacVittie TJ, Monroy RL, Patchen ML, Souza LM. Therapeutic use of recombinant human G-CSF (rhG-CSF) in a canine model of sublethal and lethal whole-body irradiation. International J Radiat Biol 57:723-736; 1990.
28. MacVittie TJ, Farese AM, Jackson W III. Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: the effect of supportive care plus administration of G-CSF. Health Phys 89:546-555; 2005.
29. Méndez-Ferrer S, Lucas D, Battista M, Frenette P. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 452:442-447; 2008.
30. Méndez-Ferrer S, Chow A, Merad M, Frenette P. Circadian rhythms influence hematopoietic stem cells. Curr Opin Hematol 16:235-242; 2009.
31. Moccia KD, Olsen CH, Mitchell JM, Landauer MR. Evaluation of hydration and nutritional gels as supportive care after total-body irradiation in mice (Mus musculus). J Am Assoc Laboratory Animal Sci 49:323-328; 2010.
32. Molineux G, Kinstler O, Briddell B, Hartley C, McElroy P, Kerzic P, Sutherland W, Stoney G, Kern B, Fletcher FA, Cohen A, Korach E, Ulich T, McNiece I, Lockbaum P, Miller-Messana MA, Gardner S, Hunt T, Schwab G. A new form of Filgrastim with sustained duration in vivo and enhanced ability to mobilize PBPC in both mice and humans. Experimental Hematol 27:1724-1734; 1999.
33. Morstyn G, Campbell L, Souza LM, Alton NK, Keech J, Green M, Sheridan W, Metcalf D, Fox R. Effect of granulocyte colony stimulating factor on neutropenia induced by cytotoxic chemotherapy. Lancet 1:667-672; 1988.
34. Nelson RF. Variation in radiosensitivity of mice with time of day. Acta Radiol Ther Phys Biol 4:91-96; 1966.
35. Okayasu R, Suetomi K, Yu Y, Silver A, Bedford JS, Cox R, Ullrich RL. A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse. Cancer Res 60:4342-4345; 2000.
36. Patchen ML. Amifostine plus granulocyte colony-stimulating factor therapy enhances recovery from supralethal radiation exposures: preclinical experience in animals models. European J Cancer 31A(Suppl 1); 1995.
37. Patchen ML, MacVittie TJ. Granulocyte colony-stimulating factor and amifostine (Ethyol) synergize to enhance hemopoietic reconstitution and increase survival in irradiated animals. Seminars Oncol 21:26-32; 1994.
38. Patchen ML, MacVittie TJ, Weiss JF. Combined modality radioprotection: the use of glucan and selenium with WR-2721.International J Radiat Oncol Biol Phys 18:1069-1075; 1990.
39. Patchen ML, MacVittie TJ, Souza LM. Postirradiation treatment with granulocyte colony-stimulating factor and preirradiation WR-2721 administration synergize to enhance hemopoietic reconstitution and increase survival. International J Radiat Oncol Biol Phys 22:773-779; 1992.
40. Pizzarello DJ, Witcofski RL, Lyons EA. Variations in survival time after whole-body radiation at two times of day. Science 139:349; 1963.
41. Pizzarello DJ, Isaak D, Chua KE, Rhyne AL. Circadian rhythmicity in the sensitivity of two strains of mice to whole-body radiation. Science 145:286-291; 1964.
42. Potten C, Al-Barwari S, Hume W, Searle J. Circadian rhythms of presumptive stem cells in three different epithelia of the mouse. Cell Tissue Kinet 10:557-568; 1977.
43. Sheridan WP, Morstyn G, Wolf M, Dodds A, Lusk J, Maher D, Layton JE, GreenMD, Souza L, FoxRM. Granulocyte colonystimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation. Lancet 2:891-895; 1989.
44. Shimamura M, Kobayashi Y, Yuo A, Urabe A, Okabe T, Komatsu Y, Itoh S, Takaku F. Effect of human recombinant granulocyte colony-stimulating factor on hematopoietic injury in mice induced by 5-fluorouracil. Blood 69:353-355; 1987.
45. Tanikawa S, Nose M, Aoki Y, Tsuneoka K, Shikita M, Nara N. Effects of recombinant human granulocyte colony-stimulating factor on the hematologic recovery and survival of irradiated mice. Blood 76:445-449; 1990.
46. Vriesendorp H, Van Bekkum D. Susceptibility to total-body irradiation. Response of different species to total body irradiaton. Amsterdam: Martinus Nijhoff; 1984.
47. Waselenko JK, MacVittie TJ, Blakely WF, Pesik N, Wiley AL, Dickerson WE, Tsu H, Confer DL, Coleman CN, Seed T, Lowry P, Armitage JO, Dainiak N. Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group. Ann Intern Med 140:1037-1051; 2004.
48. Welte K, Gabrilove J, Bronchud MH, Platzer E, Morstyn G. Filgrastim (r-metHuG-CSF): the first 10 years. Blood 88: 1907-1929; 1996.
49. Williams JP, Brown SL, Georges GE, Hauer-Jensen M, Hill RP, Huser AK, Kirsch DG, MacVittie TJ, Mason KA, Medhora MM, Moulder JE, Okunieff P, Otterson MF, Robbins ME, Smathers JB, McBride WH. Animal models for medical countermeasures to radiation exposure. Radiat Res 173: 557-578; 2010.
50. Yuhas JM, Storer JB. The effect of age on two modes of radiation death and on hematopoietic cell survival in the mouse. Radiat Res 32:596-605; 1967.
51. Yuhas JM, Yurconic M, Morton MK, West G, Peterson DF. Combined use of radioprotective and radiosensitizing drugs in experimental radiotherapy. Radiat Res 70:433-443; 1977.
52. Zsebo KM, Cohen AM, Murdock DC, Boone TC, Inoue H, Chazin VR, Hines D, Souza LM. Recombinant human granulocyte colony stimulating factor: molecular and biological characterization. Immunobiol 172:175-184; 1986.