Automated GMP Synthesis of [18F]ICMT-11 for In Vivo Imaging of Caspase-3 Activity

Nuclear Medicine and Biology

Volumn 39, Issue 7, 2012, Pages 1000-1005

  Fortt, Robin ^a   Smith, Graham ^a,c   Awais, Ramla O ^a   Luthra, Sajinder K ^b   Aboagye, Eric O ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b GE HEALTHCARE   (United Kingdom)

^c UNIVERSITY OF HULL   (United Kingdom)

Author keywords

Apoptosis; Automated radiosynthesis; Caspase 3 7; Positron emission tomography

Indexed keywords

1 [[1 (2 FLUOROETHYL) 1H [1,2,3] TRIAZOL 4YL]METHYL] 5 [2 (2,4 DIFLUOROPHENOXYMETHYL)PYRROLIDIN 1 SULFONYL]ISATIN F 18; ALKYNE; CASPASE 3; RADIOPHARMACEUTICAL AGENT; SOLVENT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOMATION; CATALYST; CHEMICAL REACTION; DRUG MANUFACTURE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; GOOD MANUFACTURING PRACTICE; IN VIVO STUDY; METHODOLOGY; PROCESS OPTIMIZATION; QUALITY CONTROL; RADIOCHEMISTRY;

AUTOMATION; AZIDES; CASPASE 3; CHEMISTRY TECHNIQUES, SYNTHETIC; INDOLES; MOLECULAR IMAGING; QUALITY CONTROL; RADIOCHEMISTRY;

EID: 84866027982     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2012.03.004     Document Type: Article

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