Synthesis, biodistribution and PET studies in rats of 18F-Labeled bridgehead fluoromethyl analogues of WAY-100635

Nuclear Medicine and Biology

Volumn 39, Issue 7, 2012, Pages 1068-1076

  Al Hussainy, Rana ^a   Verbeek, Joost ^a   der Born, Dion van ^a   Molthoff, Carla ^a   Booij, Jan ^b  

^a Koos) D M   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

5 HT1A receptor; PET; WAY 100635

Indexed keywords

4 (FLUOROMETHYL) N [2 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]ETHYL] N (PYRIDIN 2 YL)BICYCLO[2.2.1]HEPTANE 1 CARBOXAMIDE F 18; 4 (FLUOROMETHYL) N [2 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]ETHYL] N (PYRIDIN 2 YL)BICYCLO[2.2.2]OCTANE 1 CARBOXAMIDE F 18; 4 (FLUOROMETHYL) N [2 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]ETHYL] N (PYRIDIN 2 YL)CUBANE 1 CARBOXAMIDE F 18; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; RADIOLIGAND; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE; CEREBELLUM; DEFLUORINATION; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HIPPOCAMPUS; IN VIVO STUDY; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOCHEMISTRY; RAT;

ANIMALS; CHEMISTRY TECHNIQUES, SYNTHETIC; FLUORINE RADIOISOTOPES; MALE; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 84866013522     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2012.04.002     Document Type: Article

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