Characterization of leukemic cell behaviors in a soft marrow mimetic alginate hydrogel

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 100 B, Issue 7, 2012, Pages 1980-1988

  Vu, Thao Thi Thu ^a   Lim, Carine ^a   Lim, Mayasari ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

alginate hydrogel; biocompatibility; bone marrow; cell material interactions; encapsulated cells

Indexed keywords

ALGINATE HYDROGELS; BIOCHEMICAL PROPERTIES; BONE MARROW; CELL CLUSTERS; CELL CYCLE; CELL FATE DECISION; CELL SURVIVAL; CELL VIABILITY; CELL-MATERIAL INTERACTION; ENCAPSULATED CELL; HIGH-DENSITY CULTURES; IN-VITRO; LEUKEMIA CELLS; LEUKEMIC CELLS; MARROW TISSUE; RGD PEPTIDE; SPECIFIC INTERACTION;

ALGINATE; BIOCOMPATIBILITY; BIOMECHANICS; BONE; CELL GROWTH; CELL PROLIFERATION; CELLS; DISEASES; GROWTH KINETICS; HYDROGELS; MECHANICAL PROPERTIES; THREE DIMENSIONAL; TISSUE;

CELL CULTURE;

ALGINIC ACID; ARGINYLGLYCYLASPARTIC ACID;

ARTICLE; BIOCHEMISTRY; BIOPHYSICS; BONE MARROW; CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL GROWTH; CELL MATURATION; CELL POPULATION; CELL SURVIVAL; CELL VIABILITY; CONJUGATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEL; IN VITRO STUDY; LEUKEMIA CELL;

ALGINATES; BIOMIMETIC MATERIALS; BONE MARROW; CELL SURVIVAL; G2 PHASE CELL CYCLE CHECKPOINTS; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; K562 CELLS; LEUKEMIA; M PHASE CELL CYCLE CHECKPOINTS; MEGAKARYOCYTES; POLYPLOIDY;

EID: 84866004492     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.32765     Document Type: Article

References (26)

1. Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA,. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science 2008; 322: 1861-1865.
2. Damiano JS, Cress AE, Hazlehurst LA, Shtil AA, Dalton WS,. Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines. Blood 1999; 93: 1658-1667.
3. Nair RR, Tolentino J, Hazlehurst LA,. The bone marrow microenvironment as a sanctuary for minimal residual disease in CML. Biochem Pharmacol 2010; 80: 602-612.
4. Gieni RS, Hendzel MJ,. Mechanotransduction from the ECM to the genome: Are the pieces now in place? J Cell Biochem 2008; 104: 1964-1987.
5. Beyec JL, Xu R, Lee SY, Nelson CM, Rizki A, Alcaraz J, Bissell MJ,. Cell shape regulates glocal histone acetylation in human mammary epithelial cells. Exp Cell Res 2007; 313: 3066-3075.
6. Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE,. Geometric control of cell life and death. Science 1997; 276: 1425-1428.
7. Birgersdotter A, Sandberg R, Ernberg I,. Gene expression perturbation in vitro-A growing case for three-dimensional (3D) culture systems. Semin Cancer Biol 2005; 15: 405-412.
8. Rowley JA, Madlambayan G, Mooney DJ,. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 1999; 20: 45-53.
9. Drury JL, Mooney DJ,. Hydrogels for tissue engineering: Scaffold design variables and applications. Biomaterials 2003; 24: 4337-4351.
10. Eiselt P, Yeh J, Latvala RK, Shea LD, Mooney DJ,. Porous carriers for biomedical applications based on alginate hydrogels. Biomaterials 2000; 21: 1921-1927.
11. Silva EA, Mooney DJ, Gerald PS,. Synthetic extracellular matrices for tissue engineering and regeneration. Current Topics in Developmental Biology 2004; 64: 181-205.
12. Mooney DJ, Vandenburgh H,. Cell delivery mechanisms for tissue repair. Cell Stem Cell 2008; 2: 205-213.
13. Comisar WA, Kazmers NH, Mooney DJ, Linderman JJ,. Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: A combined computational and experimental approach. Biomaterials 2007; 28: 4409-4417.
14. Rowley JA, Mooney DJ,. Alginate type and RGD density control myoblast phenotype. J Biomed Mater Res 2002; 60: 217-223.
15. Drury JL, Dennis RG, Mooney DJ,. The tensile properties of alginate hydrogels. Biomaterials 2004; 25: 3187-3199.
16. Rebecca LH, David AH, Frank GT,. Transport characterization of hydrogel matrices for cell encapsulation. Biotechnol Bioeng 1996; 50: 365-373.
17. Saha K, Pollock JF, Schaffer DV, Healy KE,. Designing synthetic materials to control stem cell phenotype. Curr Opin Chem Biol 2007; 11: 381-387.
18. Fung YC,. Biomechanics: Mechanical Properties of Living Tissues. New York: Springer-Verlag New York; 1993. 568 p.
19. Erkamp RQ, Wiggins P, Skovoroda AR, Emelianov SY, O'Donnell M,. Measuring the elastic modulus of small tissue samples. Ultrasonic Imaging 1998; 20: 17-28.
20. Vu TTT, Kaur H, Lim M,. Toward a bone marrow niche: Culture of hematopoietic cells in two-dimensional versus three-dimensional microenvironments. In:, Chua C, Lee M, Guan Y, Chen J, Luo K, Lai C, Kwoh C, Lee J, Chian K, Wu S, editors. Proceedings of the First International Symposium on Bioengineering. Singapore: Research Publishing; 2011. pp 314-322.
21. Kong HJ, Smith MK, Mooney DJ,. Designing alginate hydrogels to maintain viability of immobilized cells. Biomaterials 2003; 24: 4023-4029.
22. Wanda PE,. Immunochemical detection of cell cycle synchronization in a human erythroid cell line, K562. Methods Cell Sci 1996; 18: 143-148.
23. Banavali S, Silvestri F, Hulette B, Hurtubise P, Srivastava A, Civin CI, Preisler HD,. Expression of hematopoietic progenitor cell associated antigen CD34 in chronic myeloid leukemia. Leuk Res 1991; 15: 603-608.
24. Jamieson CHM, Ailles LE, Dylla SJ, Muijtjens M, Jones C, Zehnder JL, Gotlib J, Li K, Manz MG, Keating A, Sawyers CL, Weissman IL,. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 2004; 351: 657-667.
25. Meshkini A, Yazdanparast R,. Chemosensitization of human leukemia K562 cells to taxol by a Vanadium-salen complex. Exp Mol Pathol 2010; 89: 334-342.
26. Chun-Guang W, Jun-Qing Y, Bei-Zhong L, Dan-Ting J, Chong W, Liang Z, Dan Z, Yan W,. Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur J Pharmacol 2010; 627: 33-41.