Fusion proteins of HIV-1 envelope glycoprotein gp120 with CD4-induced antibodies showed enhanced binding to CD4 and CD4 binding site antibodies

Biochemical and Biophysical Research Communications

Volumn 425, Issue 4, 2012, Pages 931-937

  Chen, Weizao ^a   Feng, Yang ^a   Wang, Yanping ^a   Zhu, Zhongyu ^a   Dimitrov, Dimiter S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

CD4; CD4bs antibody; CD4i antibody; Gp120; HIV 1; Stabilization

Indexed keywords

CD4 ANTIBODY; EPITOPE; GLYCOPROTEIN GP 120; HYBRID PROTEIN; NEUTRALIZING ANTIBODY;

ANTIBODY COMBINING SITE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STABILITY;

AIDS VACCINES; ANTIBODIES, NEUTRALIZING; ANTIGENS, CD4; BINDING SITES; EPITOPES; HEK293 CELLS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84866004315     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.013     Document Type: Article

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