Toward understanding the role of mitochondrial complex II in the intraerythrocytic stages of Plasmodium falciparum: Gene targeting of the Fp subunit

Parasitology International

Volumn 61, Issue 4, 2012, Pages 726-728

  Tanaka, Takeshi Q ^a,c   Hirai, Makoto ^b   Watanabe, Yoh Ichi ^a   Kita, Kiyoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Intraerythrocytic stage; Malaria; Succinate; Tricarboxylic acid cycle

Indexed keywords

MESSENGER RNA; POLYPEPTIDE; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ARTICLE; GENETIC DISTANCE; GROWTH RETARDATION; MITOCHONDRION; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; BIOLOGICAL MARKERS; ELECTRON TRANSPORT COMPLEX II; FUMARATES; GENE EXPRESSION REGULATION; GENE TARGETING; MUTATION; PLASMODIUM FALCIPARUM; PROTEIN SUBUNITS; SUBSTRATE SPECIFICITY; SUCCINIC ACID;

PLASMODIUM FALCIPARUM;

EID: 84865984255     PISSN: 13835769     EISSN: 18730329     Source Type: Journal    
DOI: 10.1016/j.parint.2012.06.002     Document Type: Article

References (21)

1. Roth E. Plasmodium falciparum carbohydrated metabolism: a connection between host cell and parasite. Blood Cells 1990, 16:453-460.
2. Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 2002, 419:498-511.
3. Makler M.T., Hinrichs D.J. Measurement of the lactate dehydrogenase activity Plasmodium falciparum as an assessment of parasitemia. The American Journal of Tropical Medicine and Hygiene 1993, 48:205-210.
4. 2-fixing activity in Plasmodium falciparum grown in vitro in human erythrocytes. The Journal of Protozoology 1984, 31:167-169.
5. Lang-Unnasch N. Purification and properties of Plasmodium falciparum malate dehydrogenase. Molecular and Biochemical Parasitology 1992, 50:17-25.
6. Takeo S., Kokaze A., Ng C.S., Mizuchi D., Watanabe J., Tanabe K., et al. Succinate dehydrogenase in Plasmodium falciparum mitochondria: molecular characterization of the SDHA and SDHB genes for the catalytic subunits, the flavoprotein (Fp) and iron-sulfur (Ip) subunits. Molecular and Biochemical Parasitology 2000, 107:191-205.
7. Takashima E., Takamiya S., Takeo S., Mi-ichi F., Amino H., Kita K. Isolation of mitochondria from Plasmodium falciparum showing dihydroorotate dependent respiration. Parasitology International 2001, 50:273-278.
8. Sakai C., Tomitsuka E., Esumi H., Harada S., Kita K. Mitochondrial fumarate reductase as a target of chemotherapy: from parasites to cancer cells. Biochimica et Biophysica Acta 2012, 1820:643-651.
9. Meissner M., Krejany E., Gilson P.R., de Koning-Ward T.F., Soldati D., Crabb B.S. Tetracycline analogue-regulated transgene expression in Plasmodium falciparum blood stages using Toxoplasma gondii transactivators. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:2980-2985.
10. Kobayashi T., Sato S., Takamiya S., Komaki-Yasuda K., Yano K., Hirata A., et al. Mitochondria and apicoplast of Plasmodium falciparum: behaviour on subcellular fractionation and the implication. Mitochondrion 2007, 7:125-132.
11. Krungkrai J. Purification, characterization and localization of mitochondrial dihydroorotate dehydrogenase in Plasmodium falciparum, human malaria parasite. Biochimica et Biophysica Acta 1995, 1243:351-360.
12. 1H NMR spectral pattern of perchloric acid extracts of C6 cells with growth. NMR in Biomedicine 2006, 19:223-230.
13. Pollard P.J., Brière J.J., Alam N.A., Barwell J., Barclay E., Wortham N.C., et al. Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations. Human Molecular Genetics 2005, 14:2231-2239.
14. 1H NMR spectroscopy. NMR in Biomedicine 2009, 22:292-302.
15. Nagaraj V.A., Arumugam R., Prasad D., Rangarajan P.N., Padmanaban G. Protoporphyrinogen IX oxidase from Plasmodium falciparum is anaerobic and is localized to the mitochondrion. Molecular and Biochemical Parasitology 2010, 174:44-52.
16. Olszewski K.L., Mather M.W., Morrisey J.M., Garcia B.A., Vaidya A.B., Rabinowitz J.D., et al. Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature 2010, 466:774-778.
17. Nature 2011, 469:432. Erratum in:.
18. Trager W., Jensen J.B. Human malaria parasites in continuous culture. Science 2004, 193:673-675.
19. O'Donnell R.A., Freitas-Junior L.H., Preiser P.R., Williamson D.H., Duraisingh M., McElwain T.F., et al. A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes. The EMBO Journal 2002, 21:1231-1239.
20. Wu Y., Sifri C.D., Lei H.H., Su X.Z., Wellems T.E. Transfection of Plasmodium falciparum within human red blood cells. Proceedings of the National Academy of Sciences of the United States of America 1995, 92:973-977.
21. Lambros C., Vanderberg J.P. Synchronization of Plasmodium falciparum erythrocytic stages in culture. The Journal of Parasitology 1979, 65:418-420.