Acute myeloblastic leukemia with associated BCR-ABL translocation in a dog

Veterinary Clinical Pathology

Volumn 41, Issue 3, 2012, Pages 362-368

  Figueiredo, Josely F ^a   Culver, Sarah ^b   Behling Kelly, Erica ^a   Breen, Matthew ^b,c   Friedrichs, Kristen R ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Cytogenetics; FISH; Immunophenotyping; Raleigh chromosome

Indexed keywords

BCR ABL PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD EXAMINATION; BONE MARROW; CASE REPORT; CHROMOSOME ANALYSIS; DOG; DOG DISEASE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE TRANSLOCATION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; MALE; PATHOLOGY;

ANIMALS; BONE MARROW; CYTOGENETIC ANALYSIS; DOG DISEASES; DOGS; FUSION PROTEINS, BCR-ABL; HEMATOLOGIC TESTS; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID, ACUTE; MALE; TRANSLOCATION, GENETIC;

ANIMALIA; BACTERIA (MICROORGANISMS); CANIS FAMILIARIS;

EID: 84865982358     PISSN: 02756382     EISSN: 1939165X     Source Type: Journal    
DOI: 10.1111/j.1939-165X.2012.00450.x     Document Type: Article

References (32)

1. Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100:2292-2302.
2. Jain NC, Blue JT, Grindem CB, et al. Proposed criteria for classification of acute myeloid leukemia in dogs and cats. Vet Clin Pathol. 1991;20:63-82.
3. Cruz Cardona JA, Milner R, Alleman AR, et al. BCR-ABL translocation in a dog with chronic monocytic leukemia. Vet Clin Pathol. 2011;40:40-47.
4. Breen M, Modiano JF. Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans-man and his best friend share more than companionship. Chromosome Res. 2008;16:145-154.
5. Villiers E, Baines S, Law AM, Mallows V. Identification of acute myeloid leukemia in dogs using flow cytometry with myeloperoxidase, MAC387, and a canine neutrophil-specific antibody. Vet Clin Pathol. 2006;35:55-71.
6. Vernau W, Moore PF. An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction. Vet Immunol Immunopathol. 1999;69:145-164.
7. Tasca S, Carli E, Caldin M, Menegazzo L, Furlanello T, Gallego LS. Hematologic abnormalities and flow cytometric immunophenotyping results in dogs with hematopoietic neoplasia: 210 cases (2002-2006). Vet Clin Pathol. 2009;38:2-12.
8. Adam F, Villiers E, Watson S, Coyne K, Blackwood L. Clinical pathological and epidemiological assessment of morphologically and immunologically confirmed canine leukaemia. Vet Comp Oncol. 2009;7:181-195.
9. Bennett JM, Catovsky D, Daniel MT, et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol. 1976;33:451-458.
10. Bennett JM, Catovsky D, Daniel MT, et al. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:620-625.
11. Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 30 2009;114:937-951.
12. Heerema-McKenney A, Arber DA. Acute myeloid leukemia. Hematol Oncol Clin North Am. 2009;23:633-654.
13. Vardiman JW. The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: an overview with emphasis on the myeloid neoplasms. Chem Biol Interact. 19 2010;184:16-20.
14. McManus PM, Hess RS. Myelodysplastic changes in a dog with subsequent acute myeloid leukemia. Vet Clin Pathol. 1998;27:112-115.
15. Juopperi TA, Bienzle D, Bernreuter DC, Vernau W, Thrall MA, McManus PM. Prognostic markers for myeloid neoplasms: a comparative review of the literature and goals for future investigation. Vet Pathol. 2011;48:182-197.
16. Ameri M, Wilkerson MJ, Stockham SL, Almes KM, Patton KM, Jackson T. Acute megakaryoblastic leukemia in a German Shepherd dog. Vet Clin Pathol. 2010;39:39-45.
17. Reuss-Borst MA, Buhring HJ, Schmidt H, Muller CA. AML: immunophenotypic heterogeneity and prognostic significance of c-kit expression. Leukemia. 1994;8:258-263.
18. Rowley J. Letter: a new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature. 1973;243:290-293.
19. Nowell PC, Hungerford DA. A minute chromosome in chronic granulocytic leukemia [abstract]. Science. 1960;132:1497.
20. Kurzrock R, Kantarjian HM, Druker BJ, Talpaz M. Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann Intern Med. 2003;138:819-830.
21. Thomas DA. Philadelphia chromosome positive acute lymphocytic leukemia: a new era of challenges. Hematology Am Soc Hematol Educ Program. 2007;2007:435-443.
22. Soupir CP, Vergilio JA, Dal Cin P, et al. Philadelphia chromosome-positive acute myeloid leukemia: a rare aggressive leukemia with clinicopathologic features distinct from chronic myeloid leukemia in myeloid blast crisis. Am J Clin Pathol. 2007;127:642-650.
23. Melo JV. The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood. 1996;88:2375-2384.
24. Maru Y, Witte ON. The BCR gene encodes a novel serine/threonine kinase activity within a single exon. Cell. 1991;67:459-468.
25. Wetzler M, Talpaz M, Van Etten RA, Hirsh-Ginsberg C, Beran M, Kurzrock R. Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation. J Clin Invest. 1993;92:1925-1939.
26. Cilloni D, Saglio G. CML: a model for targeted therapy. Best Pract Res Clin Haematol. 2009;22:285-294.
27. Deininger M, Buchdunger E, Druker BJ. The development of imatinib as a therapeutic agent for chronic myeloid leukemia. Blood. 2005;105:2640-2653.
28. Kirkness EF, Bafna V, Halpern AL, et al. The dog genome: survey sequencing and comparative analysis. Science. 2003;301:1898-1903.
29. Lindblad-Toh K, Wade CM, Mikkelsen TS, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 2005;438:803-819.
30. Breen M. Canine cytogenetics-from band to basepair. Cytogenet Genome Res. 2008;120:50-60.
31. Cuneo A, Ferrant A, Michaux JL, et al. Philadelphia chromosome-positive acute myeloid leukemia: cytoimmunologic and cytogenetic features. Haematologica. 1996;81:423-427.
32. Tarrant JM, Stokol T, Blue JT, McDonough SP, Farrell P. Diagnosis of chronic myelogenous leukemia in a dog using morphologic, cytochemical, and flow cytometric techniques. Vet Clin Pathol. 2001;30:19-24.