메뉴 건너뛰기




Volumn 127, Issue 4, 2007, Pages 642-650

Philadelphia chromosome-positive acute myeloid leukemia: A rare aggressive leukemia with clinicopathologic features distinct from chronic myeloid leukemia in myeloid blast crisis

Author keywords

Cytogenetics; Genetics; Hematopathology; Leukemia; Philadelphia chromosome

Indexed keywords

BCR ABL PROTEIN; GEMTUZUMAB OZOGAMICIN; IMATINIB;

EID: 34247169583     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/B4NVER1AJJ84CTUU     Document Type: Article
Times cited : (150)

References (45)
  • 1
    • 2142815402 scopus 로고    scopus 로고
    • Philadelphia chromosome positive myelodysplastic syndrome and acute myeloid leukemia: Retrospective study and review of literature
    • Keung YK, Beaty M, Powell BL, et al. Philadelphia chromosome positive myelodysplastic syndrome and acute myeloid leukemia: retrospective study and review of literature. Leuk Res. 2004;28:579-586.
    • (2004) Leuk Res , vol.28 , pp. 579-586
    • Keung, Y.K.1    Beaty, M.2    Powell, B.L.3
  • 2
    • 0031730466 scopus 로고    scopus 로고
    • Biologic heterogeneity in Philadelphia chromosome-positive acute leukemia with myeloid morphology: The Eastern Cooperative Oncology Group experience
    • Paietta E, Racevskis J, Bennett JM, et al. Biologic heterogeneity in Philadelphia chromosome-positive acute leukemia with myeloid morphology: the Eastern Cooperative Oncology Group experience. Leukemia. 1998;12:1881-1885.
    • (1998) Leukemia , vol.12 , pp. 1881-1885
    • Paietta, E.1    Racevskis, J.2    Bennett, J.M.3
  • 3
    • 0030324507 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive acute myeloid leukemia: Cytoimmunologic and cytogenetic features
    • Cuneo A, Ferrant A, Michaux JL, et al. Philadelphia chromosome-positive acute myeloid leukemia: cytoimmunologic and cytogenetic features. Haematologica. 1996;81:423-427.
    • (1996) Haematologica , vol.81 , pp. 423-427
    • Cuneo, A.1    Ferrant, A.2    Michaux, J.L.3
  • 4
    • 0027320030 scopus 로고
    • Differences between blastic chronic myeloid leukemia and Ph-positive acute leukemia
    • Berger R. Differences between blastic chronic myeloid leukemia and Ph-positive acute leukemia. Leuk Lymphoma. 1993;11(suppl 1):235-237.
    • (1993) Leuk Lymphoma , vol.11 , Issue.SUPPL. 1 , pp. 235-237
    • Berger, R.1
  • 6
    • 0026774943 scopus 로고
    • Characterization of Philadelphia-chromosome-positive acute leukemia by clinical, immunocytochemical, and gene analysis
    • Tien HF, Wang CH, Chuang SM, et al. Characterization of Philadelphia-chromosome-positive acute leukemia by clinical, immunocytochemical, and gene analysis. Leukemia. 1992;6:907-914.
    • (1992) Leukemia , vol.6 , pp. 907-914
    • Tien, H.F.1    Wang, C.H.2    Chuang, S.M.3
  • 7
    • 0014868883 scopus 로고
    • Cytogenetic studies in acute myelocytic leukemia with special emphasis on the occurrence of Ph1 chromosome
    • Whang-Peng J, Henderson ES, Knutsen T, et al. Cytogenetic studies in acute myelocytic leukemia with special emphasis on the occurrence of Ph1 chromosome. Blood. 1970;36:448-457.
    • (1970) Blood , vol.36 , pp. 448-457
    • Whang-Peng, J.1    Henderson, E.S.2    Knutsen, T.3
  • 8
    • 0032851206 scopus 로고    scopus 로고
    • Outcome of biphenotypic acute leukemia
    • Killick S, Matutes E, Powles RL, et al. Outcome of biphenotypic acute leukemia. Haematologica. 1999;84:699-706.
    • (1999) Haematologica , vol.84 , pp. 699-706
    • Killick, S.1    Matutes, E.2    Powles, R.L.3
  • 9
    • 6844259861 scopus 로고    scopus 로고
    • Adult biphenotypic acute leukaemia: An entity with poor prognosis which is related to unfavourable cytogenetics and P-glycoprotein overexpression
    • Legrand O, Perrot JY, Simonin G, et al. Adult biphenotypic acute leukaemia: an entity with poor prognosis which is related to unfavourable cytogenetics and P-glycoprotein overexpression. Br J Haematol. 1998;100:147-155.
    • (1998) Br J Haematol , vol.100 , pp. 147-155
    • Legrand, O.1    Perrot, J.Y.2    Simonin, G.3
  • 10
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: Advances in biology and new approaches to treatment
    • Goldman JM, Melo JV. Chronic myeloid leukemia: advances in biology and new approaches to treatment. N Engl J Med. 2003;349:1451-1464.
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 11
    • 0028837561 scopus 로고
    • Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL)
    • Bene MC, Castoldi G, Knapp W, et al. Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia. 1995;9:1783-1786.
    • (1995) Leukemia , vol.9 , pp. 1783-1786
    • Bene, M.C.1    Castoldi, G.2    Knapp, W.3
  • 12
    • 34247117794 scopus 로고    scopus 로고
    • Jaffe ES, Harris NL, Stein H, et al, eds. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001:351. World Health Organisation Classification of Tumours.
    • Jaffe ES, Harris NL, Stein H, et al, eds. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001:351. World Health Organisation Classification of Tumours.
  • 13
    • 0015090542 scopus 로고
    • Quantitation of bone marrow reticulin: A normal range
    • Bauermeister DE. Quantitation of bone marrow reticulin: a normal range. Am J Clin Pathol. 1971;56:24-31.
    • (1971) Am J Clin Pathol , vol.56 , pp. 24-31
    • Bauermeister, D.E.1
  • 15
    • 20944442975 scopus 로고    scopus 로고
    • Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate
    • Cortes J, Talpaz M, O'Brien S, et al. Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate. Clin Cancer Res. 2005;11:3425-3432.
    • (2005) Clin Cancer Res , vol.11 , pp. 3425-3432
    • Cortes, J.1    Talpaz, M.2    O'Brien, S.3
  • 16
    • 3242748217 scopus 로고    scopus 로고
    • Accelerated and blastic phases of chronic myelogenous leukemia
    • xii
    • Giles FJ, Cortes JE, Kantarjian HM, et al. Accelerated and blastic phases of chronic myelogenous leukemia. Hematol Oncol Clin North Am. 2004;18:753-774, xii.
    • (2004) Hematol Oncol Clin North Am , vol.18 , pp. 753-774
    • Giles, F.J.1    Cortes, J.E.2    Kantarjian, H.M.3
  • 17
    • 0037093092 scopus 로고    scopus 로고
    • Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
    • Sawyers CL, Hochhaus A, Feldman E, et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood. 2002;99:3530-3539.
    • (2002) Blood , vol.99 , pp. 3530-3539
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3
  • 18
    • 0345713156 scopus 로고    scopus 로고
    • Lowenberg B, Downing JR, Burnett A. Acute myeloid leukemia. [published correction appears in N Engl J Med. 1999;341:1484]. N Engl J Med. 1999;341:1051-1062.
    • Lowenberg B, Downing JR, Burnett A. Acute myeloid leukemia. [published correction appears in N Engl J Med. 1999;341:1484]. N Engl J Med. 1999;341:1051-1062.
  • 19
    • 0028018366 scopus 로고
    • Bone marrow cellularity in myeloid stem cell disorders: Impact of age correction
    • Tuzuner N, Cox C, Rowe JM, et al. Bone marrow cellularity in myeloid stem cell disorders: impact of age correction. Leuk Res. 1994;18:559-564.
    • (1994) Leuk Res , vol.18 , pp. 559-564
    • Tuzuner, N.1    Cox, C.2    Rowe, J.M.3
  • 20
    • 0018675904 scopus 로고
    • The reticulin content of bone marrow in acute leukaemia in adults
    • Manoharan A, Horsley R, Pitney WR. The reticulin content of bone marrow in acute leukaemia in adults. Br J Haematol. 1979;43:185-190.
    • (1979) Br J Haematol , vol.43 , pp. 185-190
    • Manoharan, A.1    Horsley, R.2    Pitney, W.R.3
  • 21
    • 0021983463 scopus 로고
    • Autopsy and clinical findings in acute leukemia and chronic myeloproliferative diseases: An evaluation of 104 patients
    • Thiele J, Laubert A, Vykoupil KF, et al. Autopsy and clinical findings in acute leukemia and chronic myeloproliferative diseases: an evaluation of 104 patients. Pathol Res Pract. 1985;179:328-336.
    • (1985) Pathol Res Pract , vol.179 , pp. 328-336
    • Thiele, J.1    Laubert, A.2    Vykoupil, K.F.3
  • 22
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
    • for the Medical Research Council Adult and Children's Leukaemia Working Parties
    • Grimwade D, Walker H, Oliver F, et al, for the Medical Research Council Adult and Children's Leukaemia Working Parties. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. Blood. 1998;92:2322-2333.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 23
    • 10744223441 scopus 로고    scopus 로고
    • Sudden onset of the blastic phase of chronic myelogenous leukemia: Patterns and implications
    • Kantarjian H, O'Brien S, Cortes J, et al. Sudden onset of the blastic phase of chronic myelogenous leukemia: patterns and implications. Cancer. 2003;98:81-85.
    • (2003) Cancer , vol.98 , pp. 81-85
    • Kantarjian, H.1    O'Brien, S.2    Cortes, J.3
  • 24
    • 0030763394 scopus 로고    scopus 로고
    • Chemotherapy-related - late occurring - Philadelphia chromosome in AML, ALL and CML: Similar events related to treatment with DNA topoisomerase II inhibitors?
    • Pedersen-Bjergaard J, Brondum-Nielsen K, Karle H, et al. Chemotherapy-related - late occurring - Philadelphia chromosome in AML, ALL and CML: similar events related to treatment with DNA topoisomerase II inhibitors? Leukemia. 1997;11:1571-1574.
    • (1997) Leukemia , vol.11 , pp. 1571-1574
    • Pedersen-Bjergaard, J.1    Brondum-Nielsen, K.2    Karle, H.3
  • 25
    • 3242800443 scopus 로고    scopus 로고
    • Clonal evolution in chronic myelogenous leukemia
    • x
    • Cortes J, O'Dwyer ME. Clonal evolution in chronic myelogenous leukemia. Hematol Oncol Clin North Am. 2004;18:671-684, x.
    • (2004) Hematol Oncol Clin North Am , vol.18 , pp. 671-684
    • Cortes, J.1    O'Dwyer, M.E.2
  • 26
    • 0023943323 scopus 로고
    • Prognostic significance of cytogenetic abnormalities in patients with chronic myelogenous leukemia
    • Przepiorka D, Thomas ED. Prognostic significance of cytogenetic abnormalities in patients with chronic myelogenous leukemia. Bone Marrow Transplant. 1988;3:113-119.
    • (1988) Bone Marrow Transplant , vol.3 , pp. 113-119
    • Przepiorka, D.1    Thomas, E.D.2
  • 27
    • 0018979186 scopus 로고    scopus 로고
    • Rowley JD. Ph1-positive leukaemia, including chronic myelogenous leukaemia. Clin Haematol. 1980;9:55-86.
    • Rowley JD. Ph1-positive leukaemia, including chronic myelogenous leukaemia. Clin Haematol. 1980;9:55-86.
  • 28
    • 0023886691 scopus 로고
    • Possible cytogenetic distinction between lymphoid and myeloid blast crisis in chronic granulocytic leukemia
    • Diez-Martin JL, Dewald GW, Pierre RV. Possible cytogenetic distinction between lymphoid and myeloid blast crisis in chronic granulocytic leukemia. Am J Hematol. 1988;27:194-203.
    • (1988) Am J Hematol , vol.27 , pp. 194-203
    • Diez-Martin, J.L.1    Dewald, G.W.2    Pierre, R.V.3
  • 29
    • 0021023450 scopus 로고
    • Philadelphia chromosome-positive adult acute leukemia with monosomy of chromosome number seven: A subgroup with poor response to therapy
    • Maddox AM, Keating MJ, Trujillo J, et al. Philadelphia chromosome-positive adult acute leukemia with monosomy of chromosome number seven: a subgroup with poor response to therapy. Leuk Res. 1983;7:509-522.
    • (1983) Leuk Res , vol.7 , pp. 509-522
    • Maddox, A.M.1    Keating, M.J.2    Trujillo, J.3
  • 30
    • 0026005505 scopus 로고
    • Significance of the P210 versus P190 molecular abnormalities in adults with Philadelphia chromosome-positive acute leukemia
    • Kantarjian HM, Talpaz M, Dhingra K, et al. Significance of the P210 versus P190 molecular abnormalities in adults with Philadelphia chromosome-positive acute leukemia. Blood. 1991;78:2411-2418.
    • (1991) Blood , vol.78 , pp. 2411-2418
    • Kantarjian, H.M.1    Talpaz, M.2    Dhingra, K.3
  • 31
    • 0037672877 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive leukemias: From basic mechanisms to molecular therapeutics
    • Kurzrock R, Kantarjian HM, Druker BJ, et al. Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann Intern Med. 2003;138:819-830.
    • (2003) Ann Intern Med , vol.138 , pp. 819-830
    • Kurzrock, R.1    Kantarjian, H.M.2    Druker, B.J.3
  • 32
    • 0029816460 scopus 로고    scopus 로고
    • The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
    • Melo JV. The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood. 1996;88:2375-2384.
    • (1996) Blood , vol.88 , pp. 2375-2384
    • Melo, J.V.1
  • 33
    • 0037049764 scopus 로고    scopus 로고
    • BCR/ABL genes and leukemic phenotype: From molecular mechanisms to clinical correlations
    • Pane F, Intrieri M, Quintarelli C, et al. BCR/ABL genes and leukemic phenotype: from molecular mechanisms to clinical correlations. Oncogene. 2002;21:8652-8667.
    • (2002) Oncogene , vol.21 , pp. 8652-8667
    • Pane, F.1    Intrieri, M.2    Quintarelli, C.3
  • 34
    • 0037399322 scopus 로고    scopus 로고
    • Perspectives on the treatment of chronic phase and advanced phase CML and Philadelphia chromosome positive ALL(1)
    • Schiffer CA, Hehlmann R, Larson R. Perspectives on the treatment of chronic phase and advanced phase CML and Philadelphia chromosome positive ALL(1). Leukemia. 2003;17:691-699.
    • (2003) Leukemia , vol.17 , pp. 691-699
    • Schiffer, C.A.1    Hehlmann, R.2    Larson, R.3
  • 35
    • 0025907179 scopus 로고
    • Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia
    • Berman E, Heller G, Santorsa J, et al. Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia. Blood. 1991;77:1666-1674.
    • (1991) Blood , vol.77 , pp. 1666-1674
    • Berman, E.1    Heller, G.2    Santorsa, J.3
  • 36
    • 0026650021 scopus 로고
    • A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group Study
    • Vogler WR, Velez-Garcia E, Weiner RS. A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: a Southeastern Cancer Study Group Study. J Clin Oncol. 1992;10:1103-1111.
    • (1992) J Clin Oncol , vol.10 , pp. 1103-1111
    • Vogler, W.R.1    Velez-Garcia, E.2    Weiner, R.S.3
  • 37
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001;344:1038-1042.
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 38
    • 0037092980 scopus 로고    scopus 로고
    • Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase
    • Kantarjian HM, Cortes J, O'Brien S, et al. Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase. Blood. 2002;99:3547-3553.
    • (2002) Blood , vol.99 , pp. 3547-3553
    • Kantarjian, H.M.1    Cortes, J.2    O'Brien, S.3
  • 39
    • 20144388183 scopus 로고    scopus 로고
    • Response and resistance in 300 patients with BCR-ABL-positive leukemias treated with imatinib in a single center: A 4.5-year follow-up
    • Lahaye T, Riehm B, Berger U, et al. Response and resistance in 300 patients with BCR-ABL-positive leukemias treated with imatinib in a single center: a 4.5-year follow-up. Cancer. 2005;103:1659-1669.
    • (2005) Cancer , vol.103 , pp. 1659-1669
    • Lahaye, T.1    Riehm, B.2    Berger, U.3
  • 40
    • 0037105560 scopus 로고    scopus 로고
    • A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
    • Ottmann OG, Druker BJ, Sawyers CL, et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood. 2002;100:1965-1971.
    • (2002) Blood , vol.100 , pp. 1965-1971
    • Ottmann, O.G.1    Druker, B.J.2    Sawyers, C.L.3
  • 41
    • 0036530228 scopus 로고    scopus 로고
    • Factors affecting duration of survival after onset of blastic transformation of chronic myeloid leukemia
    • Wadhwa J, Szydlo RM, Apperley JF, et al. Factors affecting duration of survival after onset of blastic transformation of chronic myeloid leukemia. Blood. 2002;99:2304-2309.
    • (2002) Blood , vol.99 , pp. 2304-2309
    • Wadhwa, J.1    Szydlo, R.M.2    Apperley, J.F.3
  • 42
    • 20344366536 scopus 로고    scopus 로고
    • Successful treatment with imatinib mesylate in a case of minor BCR-ABL-positive acute myelogenous leukemia
    • Ito K, Tominaga K, Suzuki T, et al. Successful treatment with imatinib mesylate in a case of minor BCR-ABL-positive acute myelogenous leukemia. Int J Hematol. 2005;81:242-245.
    • (2005) Int J Hematol , vol.81 , pp. 242-245
    • Ito, K.1    Tominaga, K.2    Suzuki, T.3
  • 43
    • 33645123016 scopus 로고    scopus 로고
    • Complete molecular remission in a patient with Philadelphia-chromosome positive acute myeloid leukemia after conventional therapy and imatinib
    • Available at, Accessed May 1, 2006
    • Jentsch-Ullrich K, Pelz AF, Braun H, et al. Complete molecular remission in a patient with Philadelphia-chromosome positive acute myeloid leukemia after conventional therapy and imatinib. Haematologca. 2004;89:ECR15. Available at http://www.haematologica.org/online/e-cases/2004/5/ecr15/index.htm. Accessed May 1, 2006.
    • (2004) Haematologca , vol.89
    • Jentsch-Ullrich, K.1    Pelz, A.F.2    Braun, H.3
  • 44
    • 0042573792 scopus 로고    scopus 로고
    • Successful treatment with imatinib mesylate for Philadelphia chromosome-positive refractory acute myeloid leukemia [in Japanese]
    • Yamaguchi M, Konishi I. Successful treatment with imatinib mesylate for Philadelphia chromosome-positive refractory acute myeloid leukemia [in Japanese]. Rinsho Ketsueki. 2003;44:254-256.
    • (2003) Rinsho Ketsueki , vol.44 , pp. 254-256
    • Yamaguchi, M.1    Konishi, I.2
  • 45
    • 18344383326 scopus 로고    scopus 로고
    • ST1571 (imatinib mesylate) reduces bone marrow cellularity and normalizes morphologic features irrespective of cytogenetic response
    • Hasserjian RP, Boecklin F, Parker S, et al. ST1571 (imatinib mesylate) reduces bone marrow cellularity and normalizes morphologic features irrespective of cytogenetic response. Am J Clin Pathol. 2002;117:360-367.
    • (2002) Am J Clin Pathol , vol.117 , pp. 360-367
    • Hasserjian, R.P.1    Boecklin, F.2    Parker, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.