Expression of 150-kDa oxygen-regulated protein (ORP150) stimulates bleomycin-induced pulmonary fibrosis and dysfunction in mice

Biochemical and Biophysical Research Communications

Volumn 425, Issue 4, 2012, Pages 818-824

  Tanaka, Ken Ichiro ^a,b   Shirai, Ayano ^a   Ito, Yosuke ^b   Namba, Takushi ^b   Tahara, Kayoko ^a   Yamakawa, Naoki ^a,b   Mizushima, Tohru ^a,b  

^a KEIO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Bleomycin; IPF; Myofibroblast; ORP150; TGF 1

Indexed keywords

BLEOMYCIN; OXYGEN REGULATED PROTEIN 150; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FIBROBLAST; FIBROSING ALVEOLITIS; LUNG MECHANICS; MOUSE; MYOFIBROBLAST; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY FAILURE;

ANIMALS; BLEOMYCIN; IDIOPATHIC PULMONARY FIBROSIS; MICE; MICE, MUTANT STRAINS; MYOFIBROBLASTS; PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 84865975722     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.158     Document Type: Article

References (29)

1. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am. J. Respir. Crit. Care Med. 2000, 161:646-664. American Thoracic Society.
2. Sheppard D. Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc. Am. Thorac. Soc. 2006, 3:413-417.
3. Kisseleva T., Brenner D.A. Fibrogenesis of parenchymal organs. Proc. Am. Thorac. Soc. 2008, 5:338-342.
4. Willis B.C., Borok Z. TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 293:L525-534.
5. Bartram U., Speer C.P. The role of transforming growth factor beta in lung development and disease. Chest 2004, 125:754-765.
6. Kim K.K., Kugler M.C., Wolters P.J., Robillard L., Galvez M.G., Brumwell A.N., Sheppard D., Chapman H.A. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc. Natl. Acad. Sci. USA 2006, 103:13180-13185.
7. Wu Z., Yang L., Cai L., Zhang M., Cheng X., Yang X., Xu J. Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse. Respir. Res. 2007, 8:1.
8. Kaufman R.J. Orchestrating the unfolded protein response in health and disease. J. Clin. Invest. 2002, 110:1389-1398.
9. Ron D. Translational control in the endoplasmic reticulum stress response. J. Clin. Invest. 2002, 110:1383-1388.
10. Zinszner H., Kuroda M., Wang X., Batchvarova N., Lightfoot R.T., Remotti H., Stevens J.L., Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 1998, 12:982-995.
11. Hoshino T., Nakaya T., Araki W., Suzuki K., Suzuki T., Mizushima T. Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. Biochem. J. 2007, 402:581-589.
12. Namba T., Hoshino T., Suemasu S., Takarada-Iemata M., Hori O., Nakagata N., Yanaka A., Mizushima T. Suppression of expression of endoplasmic reticulum chaperones by Helicobacter pylori and its role in exacerbation of non-steroidal anti-inflammatory drug-induced gastric lesions. J. Biol. Chem. 2010, 285:37302-37313.
13. Kuwabara K., Matsumoto M., Ikeda J., Hori O., Ogawa S., Maeda Y., Kitagawa K., Imuta N., Kinoshita T., Stern D.M., Yanagi H., Kamada T. Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain. J. Biol. Chem. 1996, 271:5025-5032.
14. Ozawa K., Miyazaki M., Matsuhisa M., Takano K., Nakatani Y., Hatazaki M., Tamatani T., Yamagata K., Miyagawa J., Kitao Y., Hori O., Yamasaki Y., Ogawa S. The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes. Diabetes 2005, 54:657-663.
15. Nakagomi T., Kitada O., Kuribayashi K., Yoshikawa H., Ozawa K., Ogawa S., Matsuyama T. The 150-kilodalton oxygen-regulated protein ameliorates lipopolysaccharide-induced acute lung injury in mice. Am. J. Pathol. 2004, 165:1279-1288.
16. Lawson W.E., Crossno P.F., Polosukhin V.V., Roldan J., Cheng D.S., Lane K.B., Blackwell T.R., Xu C., Markin C., Ware L.B., Miller G.G., Loyd J.E., Blackwell T.S. Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 294:L1119-L1126.
17. Korfei M., Ruppert C., Mahavadi P., Henneke I., Markart P., Koch M., Lang G., Fink L., Bohle R.M., Seeger W., Weaver T.E., Guenther A. Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 2008, 178:838-846.
18. Baek H.A., Kim D.S., Park H.S., Jang K.Y., Kang M.J., Lee D.G., Moon W.S., Chae H.J., Chung M.J. Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 2011.
19. Nogee L.M., Dunbar A.E., Wert S.E., Askin F., Hamvas A., Whitsett J.A. A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N. Engl. J. Med. 2001, 344:573-579.
20. Thomas A.Q., Lane K., Phillips J., Prince M., Markin C., Speer M., Schwartz D.A., Gaddipati R., Marney A., Johnson J., Roberts R., Haines J., Stahlman M., Loyd J.E. Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred. Am. J. Respir. Crit. Care Med. 2002, 165:1322-1328.
21. Mulugeta S., Nguyen V., Russo S.J., Muniswamy M., Beers M.F. A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation. Am. J. Respir. Cell Mol. Biol. 2005, 32:521-530.
22. Tanjore H., Cheng D.S., Degryse A.L., Zoz D.F., Abdolrasulnia R., Lawson W.E., Blackwell T.S. Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress. J. Biol. Chem. 2011, 286:30972-30980.
23. Matsuda M., Hoshino T., Yamashita Y., Tanaka K., Maji D., Sato K., Adachi H., Sobue G., Ihn H., Funasaka Y., Mizushima T. Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70. J. Biol. Chem. 2010, 285:5848-5858.
24. Tanaka K., Sato K., Aoshiba K., Azuma A., Mizushima T. Superiority of PC-SOD to other anti-COPD drugs for elastase-induced emphysema and alteration in lung mechanics and respiratory function in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 2012, 302:L1250-L1261.
25. Tanaka K., Ishihara T., Azuma A., Kudoh S., Ebina M., Nukiwa T., Sugiyama Y., Tasaka Y., Namba T., Sato K., Mizushima Y., Mizushima T. Therapeutic effect of lecithinized superoxide dismutase on bleomycin-induced pulmonary fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol. 2010, 298:L348-L360.
26. Tanaka K., Tanaka Y., Namba T., Azuma A., Mizushima T. Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice. Biochem. Pharmacol. 2010, 80:920-931.
27. Mima S., Tsutsumi S., Ushijima H., Takeda M., Fukuda I., Yokomizo K., Suzuki K., Sano K., Nakanishi T., Tomisato W., Tsuchiya T., Mizushima T. Induction of claudin-4 by nonsteroidal anti-inflammatory drugs and its contribution to their chemopreventive effect. Cancer Res. 2005, 65:1868-1876.
28. Namba T., Hoshino T., Tanaka K., Tsutsumi S., Ishihara T., Mima S., Suzuki K., Ogawa S., Mizushima T. Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells. Mol. Pharmacol. 2007, 71:860-870.
29. Ask K., Labiris R., Farkas L., Moeller A., Froese A., Farncombe T., McClelland G.B., Inman M., Gauldie J., Kolb M.R. Comparison between conventional and "clinical" assessment of experimental lung fibrosis. J. Transl. Med. 2008, 6:16.