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Volumn 109, Issue 36, 2012, Pages 14538-14543

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function

Author keywords

Herpesvirus; Immune evasion

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; CYTOKINE;

EID: 84865968749     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204836109     Document Type: Article
Times cited : (69)

References (40)
  • 1
    • 79960418128 scopus 로고    scopus 로고
    • Viral interleukin-10 expressed by human cytomegalovirus during the latent phase of infection modulates latently infected myeloid cell differentiation
    • Avdic S, Cao JZ, Cheung AK, Abendroth A, Slobedman B (2011) Viral interleukin-10 expressed by human cytomegalovirus during the latent phase of infection modulates latently infected myeloid cell differentiation. J Virol 85:7465-7471.
    • (2011) J Virol , vol.85 , pp. 7465-7471
    • Avdic, S.1    Cao, J.Z.2    Cheung, A.K.3    Abendroth, A.4    Slobedman, B.5
  • 2
    • 23844458876 scopus 로고    scopus 로고
    • Characterization of an antisense transcript spanning the UL81-82 locus of human cytomegalovirus
    • DOI 10.1128/JVI.79.17.11022-11034.2005
    • Bego M, Maciejewski J, Khaiboullina S, Pari G, St Jeor S (2005) Characterization of an antisense transcript spanning the UL81-82 locus of human cytomegalovirus. J Virol 79:11022-11034. (Pubitemid 41170643)
    • (2005) Journal of Virology , vol.79 , Issue.17 , pp. 11022-11034
    • Bego, M.1    Maciejewski, J.2    Khaiboullina, S.3    Pari, G.4    St., J.S.5
  • 3
    • 3242780176 scopus 로고    scopus 로고
    • Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations
    • DOI 10.1182/blood-2003-12-4344
    • Goodrum F, Jordan CT, Terhune SS, High K, Shenk T (2004) Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations. Blood 104:687-695. (Pubitemid 38970561)
    • (2004) Blood , vol.104 , Issue.3 , pp. 687-695
    • Goodrum, F.1    Jordan, C.T.2    Terhune, S.S.3    High, K.4    Shenk, T.5
  • 4
    • 34547948217 scopus 로고    scopus 로고
    • Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro
    • DOI 10.1182/blood-2007-01-070078
    • Goodrum F, Reeves M, Sinclair J, High K, Shenk T (2007) Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in-vitro. Blood 110:937-945. (Pubitemid 47267432)
    • (2007) Blood , vol.110 , Issue.3 , pp. 937-945
    • Goodrum, F.1    Reeves, M.2    Sinclair, J.3    High, K.4    Shenk, T.5
  • 5
    • 33845265081 scopus 로고    scopus 로고
    • Viral gene expression during the establishment of human cytomegalovirus latent infection in myeloid progenitor cells
    • DOI 10.1182/blood-2005-12-026682
    • Cheung AK, Abendroth A, Cunningham AL, Slobedman B (2006) Viral gene expression during the establishment of human cytomegalovirus latent infection in myeloid progenitor cells. Blood 108:3691-3699. (Pubitemid 44864546)
    • (2006) Blood , vol.108 , Issue.12 , pp. 3691-3699
    • Cheung, A.K.L.1    Abendroth, A.2    Cunningham, A.L.3    Slobedman, B.4
  • 6
    • 2542492369 scopus 로고    scopus 로고
    • Review: CMV escapes!
    • Froberg MK (2004) Review: CMV escapes!. Ann Clin Lab Sci 34:123-130.
    • (2004) Ann Clin Lab Sci , vol.34 , pp. 123-130
    • Froberg, M.K.1
  • 8
    • 79951777800 scopus 로고    scopus 로고
    • Human cytomegalovirus productively infects lymphatic endothelial cells and induces a secretome that promotes angiogenesis and lymphangiogenesis through interleukin-6 and granulocyte-macrophage colony-stimulating factor
    • Fiorentini S, et al. (2011) Human cytomegalovirus productively infects lymphatic endothelial cells and induces a secretome that promotes angiogenesis and lymphangiogenesis through interleukin-6 and granulocyte-macrophage colony-stimulating factor. J Gen Virol 92:650-660.
    • (2011) J Gen Virol , vol.92 , pp. 650-660
    • Fiorentini, S.1
  • 9
    • 39149113788 scopus 로고    scopus 로고
    • Human cytomegalovirus: Latency and reactivation in the myeloid lineage
    • Sinclair J (2008) Human cytomegalovirus: Latency and reactivation in the myeloid lineage. J Clin Virol 41:180-185.
    • (2008) J Clin Virol , vol.41 , pp. 180-185
    • Sinclair, J.1
  • 10
    • 0033052644 scopus 로고    scopus 로고
    • Quantitative analysis of latent human cytomegalovirus
    • Slobedman B, Mocarski ES (1999) Quantitative analysis of latent human cytomegalovirus. J Virol 73:4806-4812. (Pubitemid 29246740)
    • (1999) Journal of Virology , vol.73 , Issue.6 , pp. 4806-4812
    • Slobedman, B.1    Mocarski, E.S.2
  • 11
    • 45549090841 scopus 로고    scopus 로고
    • Human cytomegalovirus latent infection of myeloid cells directs monocyte migration by up-regulating monocyte chemotactic protein-1
    • Stern JL, Slobedman B (2008) Human cytomegalovirus latent infection of myeloid cells directs monocyte migration by up-regulating monocyte chemotactic protein-1. J Immunol 180:6577-6585.
    • (2008) J Immunol , vol.180 , pp. 6577-6585
    • Stern, J.L.1    Slobedman, B.2
  • 12
    • 76849113985 scopus 로고    scopus 로고
    • Analysis of latent viral gene expression in natural and experimental latency models of human cytomegalovirus and its correlation with histone modifications at a latent promoter
    • Reeves MB, Sinclair JH (2010) Analysis of latent viral gene expression in natural and experimental latency models of human cytomegalovirus and its correlation with histone modifications at a latent promoter. J Gen Virol 91:599-604.
    • (2010) J Gen Virol , vol.91 , pp. 599-604
    • Reeves, M.B.1    Sinclair, J.H.2
  • 13
    • 76049130197 scopus 로고    scopus 로고
    • Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility
    • Chan G, Nogalski MT, Yurochko AD (2009) Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility. Proc Natl Acad Sci USA 106:22369-22374.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 22369-22374
    • Chan, G.1    Nogalski, M.T.2    Yurochko, A.D.3
  • 14
    • 67849117043 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor (EGFR) expression by human cytomegalovirus correlates with an increase in the expression and binding of Wilms' Tumour 1 protein to the EGFR promoter
    • Jafferji I, Bain M, King C, Sinclair JH (2009) Inhibition of epidermal growth factor receptor (EGFR) expression by human cytomegalovirus correlates with an increase in the expression and binding of Wilms' Tumour 1 protein to the EGFR promoter. J Gen Virol 90:1569-1574.
    • (2009) J Gen Virol , vol.90 , pp. 1569-1574
    • Jafferji, I.1    Bain, M.2    King, C.3    Sinclair, J.H.4
  • 16
    • 70449497739 scopus 로고    scopus 로고
    • Regulatory T cells and inhibitory cytokines in autoimmunity
    • Bettini M, Vignali DA (2009) Regulatory T cells and inhibitory cytokines in autoimmunity. Curr Opin Immunol 21:612-618.
    • (2009) Curr Opin Immunol , vol.21 , pp. 612-618
    • Bettini, M.1    Vignali, D.A.2
  • 17
    • 73349109824 scopus 로고    scopus 로고
    • Temporal and spatial distribution of TGF-beta isoforms and signaling intermediates in corneal regenerative wound repair
    • Huh MI, Chang Y, Jung JC (2009) Temporal and spatial distribution of TGF-beta isoforms and signaling intermediates in corneal regenerative wound repair. Histol Histopathol 24:1405-1416.
    • (2009) Histol Histopathol , vol.24 , pp. 1405-1416
    • Huh, M.I.1    Chang, Y.2    Jung, J.C.3
  • 18
    • 21344469067 scopus 로고    scopus 로고
    • Functional role of CD105 in TGF-beta1 signalling in murine and human endothelial cells
    • Warrington K, Hillarby MC, Li C, Letarte M, Kumar S (2005) Functional role of CD105 in TGF-beta1 signalling in murine and human endothelial cells. Anticancer Res 25(3B): 1851-1864. (Pubitemid 40904577)
    • (2005) Anticancer Research , vol.25 , Issue.3 B , pp. 1851-1864
    • Warrington, K.1    Hillarby, M.C.2    Li, C.3    Letarte, M.4    Kumar, S.5
  • 19
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • Gorelik L, Flavell RA (2002) Transforming growth factor-beta in T-cell biology. Nat Rev Immunol 2:46-53. (Pubitemid 37328775)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.1 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 20
    • 0034065392 scopus 로고    scopus 로고
    • Murine models defi ne the role of TGF-beta as a master regulator of immune cell function
    • Letterio JJ (2000) Murine models defi ne the role of TGF-beta as a master regulator of immune cell function. Cytokine Growth Factor Rev 11:81-87.
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 81-87
    • Letterio, J.J.1
  • 21
    • 0037013930 scopus 로고    scopus 로고
    • Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
    • DOI 10.1084/jem.20012076
    • Gorelik L, Constant S, Flavell RA (2002) Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J Exp Med 195:1499-1505. (Pubitemid 34602827)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.11 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.2    Flavell, R.A.3
  • 22
    • 0035102549 scopus 로고    scopus 로고
    • Three-color flow cytometry detection of intracellular cytokines in peripheral blood mononuclear cells: Comparative analysis of phorbol myristate acetate-ionomycin and phytohemagglutinin stimulation
    • DOI 10.1128/CDLI.8.2.303-313.2001
    • Baran J, Kowalczyk D, Ozóg M, Zembala M (2001) Three-color flow cytometry detection of intracellular cytokines in peripheral blood mononuclear cells: Comparative analysis of phorbol myristate acetate-ionomycin and phytohemagglutinin stimulation. Clin Diagn Lab Immunol 8:303-313. (Pubitemid 32217061)
    • (2001) Clinical and Diagnostic Laboratory Immunology , vol.8 , Issue.2 , pp. 303-313
    • Baran, J.1    Kowalczyk, D.2    Ozog, M.3    Zembala, M.4
  • 24
    • 27544484202 scopus 로고    scopus 로고
    • Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL
    • Hegde NR, et al. (2005) Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL. J Exp Med 202:1109-1119.
    • (2005) J Exp Med , vol.202 , pp. 1109-1119
    • Hegde, N.R.1
  • 25
    • 77957678537 scopus 로고    scopus 로고
    • UL84-independent replication of human cytomegalovirus strain TB40/E
    • Spector DJ, Yetming K (2010) UL84-independent replication of human cytomegalovirus strain TB40/E. Virology 407:171-177.
    • (2010) Virology , vol.407 , pp. 171-177
    • Spector, D.J.1    Yetming, K.2
  • 27
    • 79960432578 scopus 로고    scopus 로고
    • Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype
    • Dziurzynski K, et al. (2011) Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype. Clin Cancer Res 17:4642-4649.
    • (2011) Clin Cancer Res , vol.17 , pp. 4642-4649
    • Dziurzynski, K.1
  • 28
    • 0037315644 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1016/S1567-5769(02)00276-X
    • Sung JL, Lin JT, Gorham JD (2003) CD28 co-stimulation regulates the effect of transforming growth factor-beta1 on the proliferation of naïve CD4+ T cells. Int Immunopharmacol 3:233-245. (Pubitemid 36183382)
    • (2003) International Immunopharmacology , vol.3 , Issue.2 , pp. 233-245
    • Sung, J.L.1    Lin, J.T.2    Gorham, J.D.3
  • 29
    • 27644457376 scopus 로고    scopus 로고
    • TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
    • Thomas DA, Massagué J (2005) TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 8:369-380.
    • (2005) Cancer Cell , vol.8 , pp. 369-380
    • Thomas, D.A.1    Massagué, J.2
  • 30
    • 79960874045 scopus 로고    scopus 로고
    • Regulation of tumor immune surveillance and tumor immune subversion by tgf-Beta
    • Park HY, Wakefield LM, Mamura M (2009) Regulation of tumor immune surveillance and tumor immune subversion by tgf-Beta. Immune Netw 9:122-126.
    • (2009) Immune Netw , vol.9 , pp. 122-126
    • Park, H.Y.1    Wakefield, L.M.2    Mamura, M.3
  • 31
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete G, et al. (1993) Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 150:353-360. (Pubitemid 23133609)
    • (1993) Journal of Immunology , vol.150 , Issue.2 , pp. 353-360
    • Del, P.G.1    De Carli, M.2    Almerigogna, F.3    Giudizi, M.G.4    Biagiotti, R.5    Romagnani, S.6
  • 32
    • 0347382454 scopus 로고    scopus 로고
    • Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes
    • DOI 10.1002/eji.200324251
    • Brady MT, MacDonald AJ, Rowan AG, Mills KH (2003) Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes. Eur J Immunol 33:3448-3457. (Pubitemid 37541123)
    • (2003) European Journal of Immunology , vol.33 , Issue.12 , pp. 3448-3457
    • Brady, M.T.1    MacDonald, A.J.2    Rowan, A.G.3    Mills, K.H.G.4
  • 33
    • 78649720282 scopus 로고    scopus 로고
    • Biology of interleukin-10
    • Sabat R, et al. (2010) Biology of interleukin-10. Cytokine Growth Factor Rev 21:331-344.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 331-344
    • Sabat, R.1
  • 34
    • 58149232443 scopus 로고    scopus 로고
    • HCMV IL-10 suppresses cytokine expression in monocytes through inhibition of nuclear factor-kappaB
    • Nachtwey J, Spencer JV (2008) HCMV IL-10 suppresses cytokine expression in monocytes through inhibition of nuclear factor-kappaB. Viral Immunol 21:477-482.
    • (2008) Viral Immunol , vol.21 , pp. 477-482
    • Nachtwey, J.1    Spencer, J.V.2
  • 35
    • 77950507790 scopus 로고    scopus 로고
    • The role of the human cytomegalovirus UL111A gene in down-regulating CD4+ T-cell recognition of latently infected cells: Implications for virus elimination during latency
    • Cheung AK, et al. (2009) The role of the human cytomegalovirus UL111A gene in down-regulating CD4+ T-cell recognition of latently infected cells: Implications for virus elimination during latency. Blood 114:4128-4137.
    • (2009) Blood , vol.114 , pp. 4128-4137
    • Cheung, A.K.1
  • 36
    • 79959309652 scopus 로고    scopus 로고
    • Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34+ progenitors
    • Poole E, McGregor Dallas SR, Colston J, Joseph RS, Sinclair J (2011) Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34+ progenitors. J Gen Virol 92:1539-1549.
    • (2011) J Gen Virol , vol.92 , pp. 1539-1549
    • Poole, E.1    McGregor Dallas, S.R.2    Colston, J.3    Joseph, R.S.4    Sinclair, J.5
  • 38
    • 27644534040 scopus 로고    scopus 로고
    • An in vitro model for the regulation of human cytomegalovirus latency and reactivation in dendritic cells by chromatin remodelling
    • DOI 10.1099/vir.0.81161-0
    • Reeves MB, Lehner PJ, Sissons JG, Sinclair JH (2005) An in vitro model for the regulation of human cytomegalovirus latency and reactivation in dendritic cells by chromatin remodelling. J Gen Virol 86:2949-2954. (Pubitemid 41555558)
    • (2005) Journal of General Virology , vol.86 , Issue.11 , pp. 2949-2954
    • Reeves, M.B.1    Lehner, P.J.2    Sissons, J.G.P.3    Sinclair, J.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.