Incomplete desorption of liquid excipients reduces the in vitro and in vivo performance of self-emulsifying drug delivery systems solidified by adsorption onto an inorganic mesoporous carrier

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2750-2760

  Van Speybroeck, Michiel ^a   Williams, Hywel D ^b   Nguyen, Tri Hung ^b   Anby, Mette U ^b   Porter, Christopher J H ^b   Augustijns, Patrick ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b MONASH UNIVERSITY   (Australia)

Author keywords

adsorption; danazol; lipid based formulations; Neusilin; self emulsifying drug delivery systems

Indexed keywords

DANAZOL; DRUG CARRIER; LIPID; NEUSILIN US2; UNCLASSIFIED DRUG;

ADSORPTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DESORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; IN VITRO STUDY; IN VIVO STUDY; LIQUID; MALE; MICROEMULSION; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID;

ADMINISTRATION, ORAL; ADSORPTION; ALUMINUM SILICATES; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DANAZOL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMULSIONS; EXCIPIENTS; LIPIDS; MAGNESIUM; MALE; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; WATER;

EID: 84865963565     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300298z     Document Type: Article

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