PH-dependent solubility of indomethacin-saccharin and carbamazepine- saccharin cocrystals in aqueous media

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2605-2612

  Alhalaweh, Amjad ^a   Roy, Lilly ^b   Rodríguez Hornedo, Naír ^b   Velaga, Sitaram P ^a  

^a LULEÅ UNIVERSITY OF TECHNOLOGY   (Sweden)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

carbamazepine; cocrystal; eutectic point; indomethacin; pH; saccharin; solubility

Indexed keywords

CARBAMAZEPINE; INDOMETACIN; SACCHARIN;

AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); CRYSTAL STRUCTURE; DRUG SOLUBILITY; IONIZATION; PH; PRIORITY JOURNAL; SOLVATION;

CALORIMETRY, DIFFERENTIAL SCANNING; CARBAMAZEPINE; CRYSTALLIZATION; HYDROGEN-ION CONCENTRATION; INDOMETHACIN; MODELS, CHEMICAL; POWDER DIFFRACTION; SACCHARIN; SOLUBILITY; WATER; X-RAY DIFFRACTION;

EID: 84865962496     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300189b     Document Type: Article

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