High-throughput cocrystal slurry screening by use of in situ Raman microscopy and multi-well plate

International Journal of Pharmaceutics

Volumn 399, Issue 1-2, 2010, Pages 52-59

  Kojima, Takashi ^a   Tsutsumi, Shunichirou ^a   Yamamoto, Katsuhiko ^a   Ikeda, Yukihiro ^a   Moriwaki, Toshiya ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Cocrystal; Crystallization; High throughput screening; Indomethacin; Polymorphism; Raman spectroscopy

Indexed keywords

BENZAMIDE; HIPPURIC ACID; INDOMETACIN; MANDELIC ACID; NICOTINAMIDE; TIOPRONIN;

ARTICLE; CONTROLLED STUDY; CRYSTAL; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG STRUCTURE; HIGH THROUGHPUT COCRYSTAL SLURRY SCREENING; HIGH THROUGHPUT SCREENING; MICROSCOPE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAMAN SPECTROMETRY; SCALE UP; THERMAL ANALYSIS; X RAY DIFFRACTION;

CRYSTALLIZATION; DRUG COMPOUNDING; EXCIPIENTS; INDOMETHACIN; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, POLARIZATION; PHARMACEUTICAL PREPARATIONS; POWDER DIFFRACTION; SPECTRUM ANALYSIS, RAMAN; X-RAY DIFFRACTION;

EID: 77956879551     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.07.055     Document Type: Article

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