메뉴 건너뛰기




Volumn 9, Issue 9, 2012, Pages 2415-2423

Nanoglue: An alternative way to display cell-internalizing peptide at the spikes of hepatitis b virus core nanoparticles for cell-targeting delivery

Author keywords

chemical cross linking; conjugation; drug and gene delivery; fluorescein; HBcAg; hepatitis B virus; oligonucleotide packaging

Indexed keywords

CELL INTERNALIZING PEPTIDE; NANOPARTICLE; PEPTIDE; PROTEINASE K; UNCLASSIFIED DRUG;

EID: 84865958225     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200389t     Document Type: Article
Times cited : (24)

References (46)
  • 1
    • 0028239908 scopus 로고
    • The third helix of the Antennapedia homeodomain translocates through biological membranes
    • Derossi, D.; Joliot, A. H.; Chassaing, G.; Prochiantz, A. The third helix of the Antennapedia homeodomain translocates through biological membranes J. Biol. Chem. 1994, 269, 10444-10450 (Pubitemid 24198241)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.14 , pp. 10444-10450
    • Derossi, D.1    Joliot, A.H.2    Chassaing, G.3    Prochiantz, A.4
  • 2
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • DOI 10.1074/jbc.272.25.16010
    • Vives, E.; Brodin, P.; Lebleu, B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus J. Biol. Chem. 1997, 272, 16010-16017 (Pubitemid 27265584)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.25 , pp. 16010-16017
    • Vives, E.1    Brodin, P.2    Lebleu, B.3
  • 3
    • 9644289511 scopus 로고    scopus 로고
    • The use of cell-penetrating peptides for drug delivery
    • DOI 10.1016/S1359-6446(04)03279-9, PII S1359644604032799
    • Temsamani, J.; Vidal, P. The use of cell-penetrating peptides for drug delivery Drug Discovery Today 2004, 9, 1012-1019 (Pubitemid 39574557)
    • (2004) Drug Discovery Today , vol.9 , Issue.23 , pp. 1012-1019
    • Temsamani, J.1    Vidal, P.2
  • 5
    • 33749015745 scopus 로고    scopus 로고
    • Targeting of hepatoma cell and suppression of tumor growth by a novel 12mer peptide fused to superantigen TSST-1
    • DOI 10.2119/2006-00011.Jiang
    • Jiang, Y. Q.; Wang, H. R.; Li, H. P.; Hao, H. J.; Zheng, Y. L.; Gu, J. Targeting of hepatoma cell and suppression of tumor growth by a novel 12 mer peptide fused to superantigen TSST-1 Mol. Med. 2006, 12, 81-87 (Pubitemid 44454095)
    • (2006) Molecular Medicine , vol.12 , Issue.4-6 , pp. 81-87
    • Jiang, Y.-Q.1    Wang, H.-R.2    Li, H.-P.3    Hao, H.-J.4    Zheng, Y.-L.5    Gu, J.6
  • 6
    • 34547401949 scopus 로고    scopus 로고
    • Screening and identification of a targeting peptide to hepatocarcinoma from a phage display peptide library
    • DOI 10.2119/2006-00115.Zhang
    • Zhang, B.; Zhang, Y.; Wang, J.; Zhang, Y.; Chen, J.; Pan, Y.; Ren, L.; Hu, Z.; Zhao, J.; Liao, M.; Wang, S. Screening and identification of a targeting peptide to hepatocarcinoma from a phage display peptide library Mol. Med. 2007, 13, 246-254 (Pubitemid 47175034)
    • (2007) Molecular Medicine , vol.13 , Issue.5-6 , pp. 246-254
    • Zhang, B.1    Zhang, Y.2    Wang, J.3    Zhang, Y.4    Chen, J.5    Pan, Y.6    Ren, L.7    Hu, Z.8    Zhao, J.9    Liao, M.10    Wang, S.11
  • 7
    • 41649119539 scopus 로고    scopus 로고
    • Hepatocellular carcinoma cell-specific peptide ligand for targeted drug delivery
    • DOI 10.1158/1535-7163.MCT-07-2359
    • Lo, A.; Lin, C. T.; Wu, H. C. Hepatocellular carcinoma cell-specific peptide ligand for targeted drug delivery Mol. Cancer Ther. 2008, 7, 579-589 (Pubitemid 351482141)
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.3 , pp. 579-589
    • Lo, A.1    Lin, C.-T.2    Wu, H.-C.3
  • 8
    • 49749141624 scopus 로고    scopus 로고
    • A peptide-based carrier for intracellular delivery of proteins into malignant glial cells in vitro
    • Wu, C.; Lo, S. L.; Boulaire, J.; Hong, M. L.; Beh, H. M.; Leung, D. S.; Wang, S. A peptide-based carrier for intracellular delivery of proteins into malignant glial cells in vitro J. Controlled Release 2008, 130, 140-145
    • (2008) J. Controlled Release , vol.130 , pp. 140-145
    • Wu, C.1    Lo, S.L.2    Boulaire, J.3    Hong, M.L.4    Beh, H.M.5    Leung, D.S.6    Wang, S.7
  • 9
    • 58449086357 scopus 로고    scopus 로고
    • A novel peptide enhances therapeutic efficacy of liposomal anti-cancer drugs in mice models of human lung cancer
    • Chang, D. K.; Lin, C. T.; Wu, C. H.; Wu, H. C. A novel peptide enhances therapeutic efficacy of liposomal anti-cancer drugs in mice models of human lung cancer PLoS One 2009, 4, e4171
    • (2009) PLoS One , vol.4 , pp. 4171
    • Chang, D.K.1    Lin, C.T.2    Wu, C.H.3    Wu, H.C.4
  • 10
    • 67349252498 scopus 로고    scopus 로고
    • Screening and identification of a peptide specifically targeted to NCI-H1299 from a phage display peptide library
    • Zang, L.; Shi, L.; Guo, J.; Pan, Q.; Wu, W.; Pan, X.; Wang, J. Screening and identification of a peptide specifically targeted to NCI-H1299 from a phage display peptide library Cancer Lett. 2009, 281, 64-70
    • (2009) Cancer Lett. , vol.281 , pp. 64-70
    • Zang, L.1    Shi, L.2    Guo, J.3    Pan, Q.4    Wu, W.5    Pan, X.6    Wang, J.7
  • 11
    • 70449337697 scopus 로고    scopus 로고
    • Use of hepadnavirus core proteins as vaccine platforms
    • Whitacre, D. C.; Lee, B. O.; Milich, D. R. Use of hepadnavirus core proteins as vaccine platforms Expert Rev. Vaccines 2009, 8, 1565-1573
    • (2009) Expert Rev. Vaccines , vol.8 , pp. 1565-1573
    • Whitacre, D.C.1    Lee, B.O.2    Milich, D.R.3
  • 12
    • 77954813062 scopus 로고    scopus 로고
    • Hepatitis B virus core protein as an epitope vaccine carrier: A review
    • Yin, Y.; Xu, J.; Chen, W. Hepatitis B virus core protein as an epitope vaccine carrier: a review Shengwu Gongcheng Xuebao 2010, 26, 431-438
    • (2010) Shengwu Gongcheng Xuebao , vol.26 , pp. 431-438
    • Yin, Y.1    Xu, J.2    Chen, W.3
  • 13
    • 0032928864 scopus 로고    scopus 로고
    • Hepatitis B core particles as a universal display model: A structure-function basis for development
    • DOI 10.1016/S0014-5793(98)01599-3, PII S0014579398015993
    • Pumpens, P.; Grens, E. Hepatitis B core particles as a universal display model: a structure-function basis for development FEBS Lett. 1999, 442, 1-6 (Pubitemid 29065366)
    • (1999) FEBS Letters , vol.442 , Issue.1 , pp. 1-6
    • Pumpens, P.1    Grens, E.2
  • 14
    • 0034889864 scopus 로고    scopus 로고
    • HBV core particles as a carrier for B cell/T cell epitopes
    • DOI 10.1159/000050037
    • Pumpens, P.; Grens, E. HBV core particles as a carrier for B cell/T cell epitopes Intervirology 2001, 44, 98-114 (Pubitemid 32757388)
    • (2001) Intervirology , vol.44 , Issue.2-3 , pp. 98-114
    • Pumpens, P.1    Grens, E.2
  • 15
    • 46749101277 scopus 로고    scopus 로고
    • Recombinant hepatitis B virus core particles: Association, dissociation and encapsidation of green fluorescent protein
    • Lee, K. W.; Tan, W. S. Recombinant hepatitis B virus core particles: association, dissociation and encapsidation of green fluorescent protein J. Virol. Methods 2008, 151, 172-180
    • (2008) J. Virol. Methods , vol.151 , pp. 172-180
    • Lee, K.W.1    Tan, W.S.2
  • 16
    • 0343279043 scopus 로고    scopus 로고
    • Packaging of up to 240 subunits of a 17 kDa nuclease into the interior of recombinant hepatitis B virus capsids
    • Beterams, G.; Böttcher, B.; Nassal, M. Packaging of up to 240 subunits of a 17 kDa nuclease into the interior of recombinant hepatitis B virus capsids FEBS Lett. 2000, 481, 169-176
    • (2000) FEBS Lett. , vol.481 , pp. 169-176
    • Beterams, G.1    Böttcher, B.2    Nassal, M.3
  • 17
    • 0026684254 scopus 로고
    • Topological analysis of the hepatitis B virus core particle by cysteine-cysteine cross-linking
    • Nassal, M.; Rieger, A.; Steinau, O. Topological analysis of the hepatitis B virus core particle by cysteine-cysteine cross-linking J. Mol. Biol. 1992, 225, 1013-1025
    • (1992) J. Mol. Biol. , vol.225 , pp. 1013-1025
    • Nassal, M.1    Rieger, A.2    Steinau, O.3
  • 18
    • 0026793044 scopus 로고
    • The Structure of hepadnaviral core antigens: Identification of free thiols and determination of the disulfide bonding pattern
    • Zheng, J.; Schödel, F.; Peterson, D. L. The Structure of hepadnaviral core antigens: identification of free thiols and determination of the disulfide bonding pattern J. Biol. Chem. 1992, 267, 9422-9429
    • (1992) J. Biol. Chem. , vol.267 , pp. 9422-9429
    • Zheng, J.1    Schödel, F.2    Peterson, D.L.3
  • 19
    • 0030949436 scopus 로고    scopus 로고
    • Folding and assembly of hepatitis B virus core protein: A new model proposal
    • DOI 10.1006/jsbi.1997.3846
    • Bringas, R. Folding and assembly of hepatitis B virus core protein: a new model proposal J. Struct. Biol. 1997, 118, 189-196 (Pubitemid 27239874)
    • (1997) Journal of Structural Biology , vol.118 , Issue.3 , pp. 189-196
    • Bringas, R.1
  • 20
    • 0033152857 scopus 로고    scopus 로고
    • The crystal structure of the human hepatitis B virus capsid
    • DOI 10.1016/S1097-2765(01)80009-5
    • Wynne, S. A.; Crowther, R. A.; Leslie, A. G. The crystal structure of the human hepatitis B virus capsid Mol. Cell 1999, 3, 771-780 (Pubitemid 29323055)
    • (1999) Molecular Cell , vol.3 , Issue.6 , pp. 771-780
    • Wynne, S.A.1    Crowther, R.A.2    Leslie, A.G.W.3
  • 22
    • 0018760172 scopus 로고
    • Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322
    • DOI 10.1038/279043a0
    • Burrell, C. J.; MacKay, P.; Greenaway, P. J.; Hofschneider, P. H.; Murray, K. Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322 Nature 1979, 279, 43-47 (Pubitemid 9157566)
    • (1979) Nature , vol.279 , Issue.5708 , pp. 43-47
    • Burrell, C.J.1    Mackay, P.2    Greenaway, P.J.3
  • 23
    • 0028307177 scopus 로고
    • Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy
    • DOI 10.1016/0092-8674(94)90142-2
    • Crowther, R. A.; Kiselev, N. A.; Böttcher, B.; Berriman, J. A.; Borisova, G. P.; Ose, V.; Pumpens, P. Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy Cell 1994, 77, 943-950 (Pubitemid 24187691)
    • (1994) Cell , vol.77 , Issue.6 , pp. 943-950
    • Crowther, R.A.1    Kiselev, N.A.2    Bottcher, B.3    Berriman, J.A.4    Borisova, G.P.5    Ose, V.6    Pumpens, P.7
  • 24
    • 0018694215 scopus 로고
    • Hepatitis B virus genes and their expression in E. coli
    • DOI 10.1038/282575a0
    • Pasek, M.; Goto, T.; Gilbert, W.; Zink, B.; Schaller, H.; MacKay, P.; Leadbetter, G.; Murray, K. Hepatitis B virus genes and their expression in E. coli Nature 1979, 282, 575-579 (Pubitemid 10213912)
    • (1979) Nature , vol.282 , Issue.5739 , pp. 575-579
    • Pasek, M.1    Goto, T.2    Gilbert, W.3
  • 25
    • 0038405161 scopus 로고    scopus 로고
    • Hepatitis B virus core antigen: Enhancement of its production in Escherichia coli, and interaction of the core particles with the viral surface antigen
    • DOI 10.1515/BC.2003.042
    • Tan, W. S.; Dyson, M. R.; Murray, K. Hepatitis B virus core antigen: enhancement of its production in Escherichia coli, and interaction of the core particles with the viral surface antigen Biol. Chem. 2003, 384, 363-371 (Pubitemid 36527643)
    • (2003) Biological Chemistry , vol.384 , Issue.3 , pp. 363-371
    • Tan, W.S.1    Dyson, M.R.2    Murray, K.3
  • 26
    • 12344258790 scopus 로고    scopus 로고
    • Recombinant viral capsids as an efficient vehicle of oligonucleotide delivery into cells
    • DOI 10.1016/j.bbrc.2004.12.118, PII S0006291X04028463
    • Cooper, A.; Shaul, Y. Recombinant viral capsids as an efficient vehicle of oligonucleotide delivery into cells Biochem. Biophys. Res. Commun. 2005, 327, 1094-1099 (Pubitemid 40137981)
    • (2005) Biochemical and Biophysical Research Communications , vol.327 , Issue.4 , pp. 1094-1099
    • Cooper, A.1    Shaul, Y.2
  • 27
    • 33745195474 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis and lysosomal cleavage of hepatitis B virus capsid-like core particles
    • Cooper, A.; Shaul, Y. Clathrin-mediated endocytosis and lysosomal cleavage of hepatitis B virus capsid-like core particles J. Biol. Chem. 2006, 281, 16563-16569
    • (2006) J. Biol. Chem. , vol.281 , pp. 16563-16569
    • Cooper, A.1    Shaul, Y.2
  • 28
    • 0028953769 scopus 로고
    • Hepatitis B core antigen produced in Escherichia coli: Subunit composition, conformational analysis, and in vitro capsid assembly
    • Wingfield, P. T.; Stahl, S. J.; Williams, R. W.; Steven, A. C. Hepatitis B core antigen produced in Escherichia coli: subunit composition, conformational analysis, and in vitro capsid assembly Biochemistry 1995, 34, 4919-4932
    • (1995) Biochemistry , vol.34 , pp. 4919-4932
    • Wingfield, P.T.1    Stahl, S.J.2    Williams, R.W.3    Steven, A.C.4
  • 29
    • 0342655940 scopus 로고    scopus 로고
    • Hybrid hepatitis B virus core antigen as a vaccine carrier moiety: I. Presentation of foreign epitopes
    • DOI 10.1016/0168-1656(95)00118-2
    • Schödel, F.; Peterson, D.; Hughes, J.; Wirtz, R.; Milich, D. Hybrid hepatitis B virus core antigen as a vaccine carrier moiety: I. presentation of foreign epitopes J. Biotechnol. 1996, 44, 91-96 (Pubitemid 26056566)
    • (1996) Journal of Biotechnology , vol.44 , Issue.1-3 , pp. 91-96
    • Schodel, F.1    Peterson, D.2    Hughes, J.3    Wirtz, R.4    Milich, D.5
  • 30
    • 0033052635 scopus 로고    scopus 로고
    • Characterization of potential insertion sites in the core antigen of hepatitis B virus by the use of a short-sized model epitope
    • DOI 10.1159/000024960
    • Lachmann, S.; Meisel, H.; Muselmann, C.; Koletzki, D.; Gelderblom, H. R.; Borisova, G.; Krüger, D. H.; Pumpens, P.; Ulrich, R. Characterization of potential insertion sites in the core antigen of hepatitis B virus by the use of a short-sized model epitope Intervirology 1999, 42, 51-56 (Pubitemid 29286902)
    • (1999) Intervirology , vol.42 , Issue.1 , pp. 51-56
    • Lachmann, S.1    Meisel, H.2    Muselmann, C.3    Koletzki, D.4    Gelderblom, H.R.5    Borisova, G.6    Kruger, D.H.7    Pumpens, P.8    Ulrich, R.9
  • 31
    • 0034715573 scopus 로고    scopus 로고
    • Puumala (PUU) hantavirus strain differences and insertion positions in the hepatitis B virus core antigen influence B-cell immunogenicity and protective potential of core-derived particles
    • Koletzki, D.; Lundkvist, A.; Sjölander, K. B.; Gelderblom, H. R.; Niedrig, M.; Meisel, H.; Krüger, D. H.; Ulrich, R. Puumala (PUU) hantavirus strain differences and insertion positions in the hepatitis B virus core antigen influence B-cell immunogenicity and protective potential of core-derived particles Virology 2000, 276, 364-375
    • (2000) Virology , vol.276 , pp. 364-375
    • Koletzki, D.1    Lundkvist, A.2    Sjölander, K.B.3    Gelderblom, H.R.4    Niedrig, M.5    Meisel, H.6    Krüger, D.H.7    Ulrich, R.8
  • 32
    • 33745223883 scopus 로고    scopus 로고
    • Hepatitis B virus capsid-like particles can display the complete, dimeric outer surface protein C and stimulate production of protective antibody responses against Borrelia burgdorferi infection
    • Skamel, C.; Ploss, M.; Böttcher, B.; Stehle, T.; Wallich, R.; Simon, M. M.; Nassal, M. Hepatitis B virus capsid-like particles can display the complete, dimeric outer surface protein C and stimulate production of protective antibody responses against Borrelia burgdorferi infection J. Biol. Chem. 2006, 281, 17474-17481
    • (2006) J. Biol. Chem. , vol.281 , pp. 17474-17481
    • Skamel, C.1    Ploss, M.2    Böttcher, B.3    Stehle, T.4    Wallich, R.5    Simon, M.M.6    Nassal, M.7
  • 33
    • 33947609904 scopus 로고    scopus 로고
    • Enhanced immunogenicity of modified hepatitis B virus core particle fused with multiepitopes of foot-and-mouth disease virus
    • DOI 10.1111/j.1365-3083.2007.01900.x
    • Zhang, Y. L.; Guo, Y. J.; Wang, K. Y.; Lu, K.; Li, K.; Zhu, Y.; Sun, S. H. Enhanced immunogenicity of modified hepatitis B virus core particle fused with multiepitopes of foot-and-mouth disease virus Scand. J. Immunol. 2007, 65, 320-328 (Pubitemid 46481099)
    • (2007) Scandinavian Journal of Immunology , vol.65 , Issue.4 , pp. 320-328
    • Zhang, Y.-L.1    Guo, Y.-J.2    Wang, K.-Y.3    Lu, K.4    Li, K.5    Zhu, Y.6    Sun, S.-H.7
  • 34
    • 36749022937 scopus 로고    scopus 로고
    • Development of hepatitis B virus capsids into a whole-chain protein antigen display platform: New particulate Lyme disease vaccines
    • DOI 10.1016/j.ijmm.2007.08.002, PII S1438422107001129, New Vaccinations Strategies
    • Nassal, M.; Skamel, C.; Vogel, M.; Kratz, P. A.; Stehle, T.; Wallich, R.; Simon, M. M. Development of hepatitis B virus capsids into a whole-chain protein antigen display platform: new particulate Lyme disease vaccines Int. J. Med. Microbiol. 2008, 298, 135-142 (Pubitemid 350216556)
    • (2008) International Journal of Medical Microbiology , vol.298 , Issue.1-2 , pp. 135-142
    • Nassal, M.1    Skamel, C.2    Vogel, M.3    Kratz, P.A.4    Stehle, T.5    Wallich, R.6    Simon, M.M.7
  • 35
    • 0028928193 scopus 로고
    • Selection of peptide inhibitors of interactions involved in complex protein assemblies: Association of the core and surface antigens of hepatitis B virus
    • Dyson, M. R.; Murray, K. Selection of peptide inhibitors of interactions involved in complex protein assemblies: association of the core and surface antigens of hepatitis B virus Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 2194-2198
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 2194-2198
    • Dyson, M.R.1    Murray, K.2
  • 36
    • 0343147172 scopus 로고    scopus 로고
    • Peptides that block hepatitis B virus assembly: Analysis by cryomicroscopy, mutagenesis and transfection
    • Böttcher, B.; Tsuji, N.; Takahashi, H.; Dyson, M. R.; Zhao, S.; Crowther, R. A.; Murray, K. Peptides that block hepatitis B virus assembly: analysis by cryomicroscopy, mutagenesis and transfection EMBO J. 1998, 17, 6839-6845 (Pubitemid 28550277)
    • (1998) EMBO Journal , vol.17 , Issue.23 , pp. 6839-6845
    • Bottcher, B.1    Tsuji, N.2    Takahashi, H.3    Dyson, M.R.4    Zhao, S.5    Crowther, R.A.6    Murray, K.7
  • 37
    • 36148964724 scopus 로고    scopus 로고
    • Interactions of hepatitis B core antigen and peptide inhibitors
    • DOI 10.1021/jm070468d
    • Tang, K. F.; Abdullah, M. P.; Yusoff, K.; Tan, W. S. Interactions of the hepatitis B core antigen and peptide inhibitors J. Med. Chem. 2007, 50, 5620-5626 (Pubitemid 350106017)
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.23 , pp. 5620-5626
    • Kah, F.T.1    Abdullah, M.P.2    Yusoff, K.3    Tan, W.S.4
  • 39
    • 33747159901 scopus 로고    scopus 로고
    • Heat treatment of unclarified Escherichia coli homogenate improved the recovery efficiency of recombinant hepatitis B core antigen
    • DOI 10.1016/j.jviromet.2006.06.016, PII S0166093406002242
    • Ng, M. Y.; Tan, W. S.; Abdullah, N.; Ling, T. C.; Tey, B. T. Heat treatment of unclarified Escherichia coli homogenate improved the recovery efficiency of recombinant hepatitis B core antigen J. Virol. Methods 2006, 137, 134-139 (Pubitemid 44226391)
    • (2006) Journal of Virological Methods , vol.137 , Issue.1 , pp. 134-139
    • Ng, M.Y.T.1    Tan, W.S.2    Abdullah, N.3    Ling, T.C.4    Tey, B.T.5
  • 40
    • 0030589816 scopus 로고    scopus 로고
    • Preferential labeling of α-amino N-terminal groups in peptides by biotin: Application to the detection of specific anti-peptide antibodies by enzyme immunoassays
    • DOI 10.1016/S0022-1759(96)00173-1, PII S0022175996001731
    • Sélo, I.; Négroni, L.; Créminon, C.; Grassi, J.; Wal, J. M. Preferential labeling of alpha-amino N-terminal groups in peptides by biotin: application to the detection of specific anti-peptide antibodies by enzyme immunoassays J. Immunol. Methods 1996, 199, 127-138 (Pubitemid 26412942)
    • (1996) Journal of Immunological Methods , vol.199 , Issue.2 , pp. 127-138
    • Selo, I.1    Negroni, L.2    Creminon, C.3    Grassi, J.4    Wal, J.M.5
  • 41
    • 0034237577 scopus 로고    scopus 로고
    • Protein transduction: Unrestricted delivery into all cells?
    • DOI 10.1016/S0962-8924(00)01771-2, PII S0962892400017712
    • Schwarze, S. R.; Hruska, K. A.; Dowdy, S. F. Protein transduction: unrestricted delivery into all cells? Trends Cell Biol. 2000, 10, 290-295 (Pubitemid 30387038)
    • (2000) Trends in Cell Biology , vol.10 , Issue.7 , pp. 290-295
    • Schwarze, S.R.1    Hruska, K.A.2    Dowdy, S.F.3
  • 43
    • 77952146840 scopus 로고    scopus 로고
    • Cell-penetrating peptides-mechanisms of cellular uptake and generation of delivery systems
    • Trabulo, S.; Cardoso, A. L.; Mano, M.; de Lima, M. C. P. Cell-penetrating peptides-mechanisms of cellular uptake and generation of delivery systems Pharmaceuticals 2010, 3, 961-993
    • (2010) Pharmaceuticals , vol.3 , pp. 961-993
    • Trabulo, S.1    Cardoso, A.L.2    Mano, M.3    De Lima, M.C.P.4
  • 44
    • 33748741173 scopus 로고    scopus 로고
    • Adaptations of nanoscale viruses and other protein cages for medical applications
    • DOI 10.1016/j.nano.2006.07.009, PII S1549963406001079
    • Lee, L. A.; Wang, Q. Adaptations of nanoscale viruses and other protein cages for medical applications Nanomedicine 2006, 2, 137-149 (Pubitemid 44403221)
    • (2006) Nanomedicine: Nanotechnology, Biology, and Medicine , vol.2 , Issue.3 , pp. 137-149
    • Lee, L.A.1    Wang, Q.2
  • 45
    • 42449132988 scopus 로고    scopus 로고
    • Killing cancer cells by targeted drug-carrying phage nanomedicines
    • Bar, H.; Yacoby, I.; Benhar, I. Killing cancer cells by targeted drug-carrying phage nanomedicines BMC Biotechnol. 2008, 8, 1-14
    • (2008) BMC Biotechnol. , vol.8 , pp. 1-14
    • Bar, H.1    Yacoby, I.2    Benhar, I.3
  • 46
    • 58449086357 scopus 로고    scopus 로고
    • A novel peptide enhances therapeutic efficacy of liposomal anti-cancer drugs in mice models of human lung cancer
    • Chang, D. K.; Lin, C. T.; Wu, C. H.; Wu, H. C. A novel peptide enhances therapeutic efficacy of liposomal anti-cancer drugs in mice models of human lung cancer PLoS One 2009, 4, e4171
    • (2009) PLoS One , vol.4 , pp. 4171
    • Chang, D.K.1    Lin, C.T.2    Wu, C.H.3    Wu, H.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.