Fate of pharmaceuticals in rivers: Deriving a benchmark dataset at favorable attenuation conditions

Water Research

Volumn 46, Issue 17, 2012, Pages 5551-5565

  Kunkel, Uwe ^a   Radke, Michael ^a,b  

^a UNIVERSITY OF BAYREUTH   (Germany)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Attenuation; Biotransformation; Enantiomer fraction; Pharmaceuticals; Phototransformation

Indexed keywords

AMIDES; BIOCONVERSION; DRUG PRODUCTS; ENANTIOMERS; IMPORTANCE SAMPLING; PHOTOLYSIS; SEDIMENTS; SEWAGE TREATMENT PLANTS;

AQUATIC ENVIRONMENTS; ATTENUATION; BIOTRANSFORMATION; ENANTIOMER FRACTIONS; FAVORABLE CONDITIONS; ORGANIC MICRO-POLLUTANTS; PHARMACEUTICAL RESIDUES; PHOTOTRANSFORMATIONS;

RIVERS;

CARBAMAZEPINE; DICLOFENAC; PROPRANOLOL; RAIN; SOTALOL; SULFAMETHOXAZOLE;

AQUATIC ENVIRONMENT; BIOTRANSFORMATION; CONCENTRATION (COMPOSITION); DATA SET; DRUG; ENVIRONMENTAL FATE; FLUVIAL DEPOSIT; FRACTIONATION; ORGANIC POLLUTANT; POLLUTANT REMOVAL; RAINFALL; RIVER DISCHARGE; RIVER POLLUTION; SEWAGE TREATMENT;

ARTICLE; BIOTRANSFORMATION; DOWNSTREAM PROCESSING; DRUG INDUSTRY; GERMANY; HYDROLOGY; INDUSTRIAL WASTE; METEOROLOGICAL PHENOMENA; PHOTOLYSIS; PRIORITY JOURNAL; QUALITY CONTROL; RIVER; SEWAGE TREATMENT PLANT; WASTE WATER MANAGEMENT;

GERMANY;

EID: 84865957464     PISSN: 00431354     EISSN: 18792448     Source Type: Journal    
DOI: 10.1016/j.watres.2012.07.033     Document Type: Article

References (42)

1. Al-Rajab A.J., Sabourin L., Lapen D.R., Topp E. The non-steroidal anti-inflammatory drug diclofenac is readily biodegradable in agricultural soils. Science of the Total Environment 2010, 409(1):78-82.
2. Andreozzi R., Raffaele M., Nicklas P. Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere 2003, 50(10):1319-1330.
3. Bartels P., von Tümpling W. Solar radiation influence on the decomposition process of diclofenac in surface waters. Science of the Total Environment 2007, 374(1):143-155.
4. Bendz D., Paxeus N.A., Ginn T.R., Loge F.J. Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Hoje River in Sweden. Journal of Hazardous Materials 2005, 122(3):195-204.
5. Buser H.R., Poiger T., Muller M.D. Occurrence and fate of the pharmaceutical drug diclofenac in surface waters: rapid photodegradation in a lake. Environmental Science & Technology 1998, 32(22):3449-3456.
6. Calisto V., Domingues M.R.M., Erny G.L., Esteves V.I. Direct photodegradation of carbamazepine followed by micellar electrokinetic chromatography and mass spectrometry. Water Research 2011, 45(3):1095-1104.
7. Canonica S., Meunier L., Von Gunten U. Phototransformation of selected pharmaceuticals during UV treatment of drinking water. Water Research 2008, 42:121-128.
8. Cardenas M.B., Wilson J.L., Zlotnik V.A. Impact of heterogeneity, bed forms, and stream curvature on subchannel hyporheic exchange. Water Resources Research 2004, 40(8).
9. Clara M., Strenn B., Kreuzinger N. Carbamazepine as a possible anthropogenic marker in the aquatic environment: investigations on the behaviour of Carbamazepine in wastewater treatment and during groundwater infiltration. Water Research 2004, 38(4):947-954.
10. Daneshvar A., Svanfelt J., Kronberg L., Prevost M., Weyhenmeyer G.A. Seasonal variations in the occurrence and fate of basic and neutral pharmaceuticals in a Swedish river-lake system. Chemosphere 2010, 80(3):301-309.
11. Defoin A., Defoin-Straatmann R., Hildenbrand K., Bittersmann E., Kreft D., Kuhn H.J. A new liquid phase actinometer: quantum yield and photo-CIDNP study of phenylglyoxylic acid in aqueous solution. Journal of Photochemistry 1986, 33(2):237-255.
12. Elliott A.H., Brooks N.H. Transfer of nonsorbing solutes to a streambed with bed forms: laboratory experiments. Water Resources Research 1997, 33(1):137-151.
13. Fono L.J., Kolodziej E.P., Sedlak D.L. Attenuation of wastewater-derived contaminants in an effluent-dominated river. Environmental Science & Technology 2006, 40(23):7257-7262.
14. Huehnerfuss H., Shah M.R. Enantioselective chromatography - a powerful tool for the discrimination of biotic and abiotic transformation processes of chiral environmental pollutants. Journal of Chromatography A 2009, 1216(3):481-502.
15. Kilpatrick F.A., Wilson J.F. Measurement of Time of Travel in Streams by Dye Tracing 1989, USGS, TWI 03-A9.
16. Kunkel U., Radke M. Biodegradation of acidic pharmaceuticals in bed sediments: insight from a laboratory experiment. Environmental Science & Technology 2008, 42(19):7273-7279.
17. Kunkel U., Radke M. Reactive tracer test to evaluate the fate of pharmaceuticals in rivers. Environmental Science & Technology 2011, 45(15):6296-6302.
18. Lahti M., Oikari A. Microbial transformation of pharmaceuticals naproxen, Bisoprolol, and diclofenac in aerobic and anaerobic environments. Archives of Environmental Contamination and Toxicology 2011, 61(2):202-210.
19. Lavén M., Alsberg T., Yu Y., Adolfsson-Erici M., Sun H. Serial mixed-mode cation- and anion-exchange solid-phase extraction for separation of basic, neutral and acidic pharmaceuticals in wastewater and analysis by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Journal of Chromatography A 2009, 1216(1):49-62.
20. Lewandowski J., Putschew A., Schwesig D., Neumann C., Radke M. Fate of organic micropollutants in the hyporheic zone of a eutrophic lowland stream: results of a preliminary field study. Science of the Total Environment 2011, 409(10):1824-1835.
21. Lewandowski J., Angermann L., Nützmann G., Fleckenstein J.H. A heat pulse technique for the determination of small-scale flow directions and flow velocities in the streambed of sand-bed streams. Hydrological Processes 2011, 25(20):3244-3255.
22. Lin A.Y.C., Plumlee M.H., Reinhard M. Natural attenuation of pharmaceuticals and alkylphenol polyethoxylate metabolites during river transport: photochemical and biological transformation. Environmental Toxicology and Chemistry 2006, 25(6):1458-1464.
23. Löffler D., Römbke J., Meller M., Ternes T.A. Environmental fate of pharmaceuticals in water/sediment systems. Environmental Science & Technology 2005, 39(14):5209-5218.
24. Meyer B., Pailler J., Guignard C., Hoffmann L., Krein A. Concentrations of dissolved herbicides and pharmaceuticals in a small river in Luxembourg. Environmental Monitoring and Assessment 2011, 180(1-4):127-146.
25. Moore D.E., Zhou W. Photodegradation of sulfamethoxazole: a chemical system capable of monitoring seasonal changes in UVB intensity. Photochemistry and Photobiology 1994, 59(5):497-502.
26. Neamţu M., Frimmel F.H. Photodegradation of endocrine disrupting chemical nonylphenol by simulated solar UV-irradiation. Science of the Total Environment 2006, 369(1-3):295-306.
27. Nödler K., Licha T., Fischer S., Wagner B., Sauter M. A case study on the correlation of micro-contaminants and potassium in the Leine River (Germany). Applied Geochemistry 2011, 26(12):2172-2180.
28. Packer J.L., Werner J.J., Latch D.E., McNeill K., Arnold W.A. Photochemical fate of pharmaceuticals in the environment: naproxen, diclofenac, clofibric acid, and ibuprofen. Aquatic Sciences 2003, 65(4):342-351.
29. Packman A., Salehin M., Zaramella M. Hyporheic exchange with gravel beds: basic hydrodynamic interactions and bedform-induced advective flows. Journal of Hydraulic Engineering-ASCE 2004, 130(7):647-656.
30. Piram A., Salvador A., Verne C., Herbreteau B., Faure R. Photolysis of beta-blockers in environmental waters. Chemosphere 2008, 73(8):1265-1271.
31. R Development Core Team R: a Language and Environment for Statistical Computing 2011, R Foundation for Statistical Computing, Vienna, Austria.
32. Radke M., Lauwigi C., Heinkele G., Mürdter T.E., Letzel M. Fate of the antibiotic sulfamethoxazole and its two major human metabolites in a water sediment test. Environmental Science & Technology 2009, 43(9):3135-3141.
33. Radke M., Ulrich H., Wurm C., Kunkel U. Dynamics and attenuation of acidic pharmaceuticals along a river stretch. Environmental Science & Technology 2010, 44(8):2968-2974.
34. Ramil M., El Aref T., Fink G., Scheurer M., Ternes T.A. Fate of beta blockers in aquatic-sediment systems: sorption and biotransformation. Environmental Science & Technology 2010, 44(3):962-970.
35. Robinson P.F., Liu Q.T., Riddle A.M., Murray-Smith R. Modeling the impact of direct phototransformation on predicted environmental concentrations (PECs) of propranolol hydrochloride in UK and US rivers. Chemosphere 2007, 66(4):757-766.
36. Sacher F., Ehmann M., Gabriel S., Graf C., Brauch H.J. Pharmaceutical residues in the river Rhine - results of a one-decade monitoring programme. Journal of Environmental Monitoring 2008, 10(5):664-670.
37. Schwarzenbach R.P., Gschwend P.M., Imboden D.M. Environmental Organic Chemistry 2003, Wiley-Interscience, New York.
38. Ternes T.A. Occurrence of drugs in German sewage treatment plants and rivers. Water Research 1998, 32(11):3245-3260.
39. Tiehm A., Schmidt N., Stieber M., Sacher F., Wolf L., Hoetzl H. Biodegradation of pharmaceutical compounds and their occurrence in the Jordan Valley. Water Resources Management 2011, 25(4):1195-1203.
40. Tixier C., Singer H.P., Oellers S., Müller S.R. Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters. Environmental Science & Technology 2003, 37(6):1061-1068.
41. Vanderford B.J., Mawhinney D.B., Trenholm R.A., Zeigler-Holady J.C., Snyder S.A. Assessment of sample preservation techniques for pharmaceuticals, personal care products, and steroids in surface and drinking water. Analytical and Bioanalytical Chemistry 2011, 399(6):2227-2234.
42. Xu B.B., Chen Z.L., Qi F., Shen J.M., Wu F.C. Factors influencing the photodegradation of N-nitrosodimethylamine in drinking water. Frontiers of Environmental Science & Engineering in China 2009, 3(1):91-97.