-
1
-
-
77950847051
-
FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells
-
Abel E.V., Aplin A.E. FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells. Cancer Research 2010, 70:2891-2900.
-
(2010)
Cancer Research
, vol.70
, pp. 2891-2900
-
-
Abel, E.V.1
Aplin, A.E.2
-
2
-
-
33847654696
-
OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer
-
Atlasi Y., Mowla S.J., Ziaee S.A., Bahrami A.R. OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer. International Journal of Cancer 2007, 120:1598-1602.
-
(2007)
International Journal of Cancer
, vol.120
, pp. 1598-1602
-
-
Atlasi, Y.1
Mowla, S.J.2
Ziaee, S.A.3
Bahrami, A.R.4
-
3
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., Dewhirst M.W., Bigner D.D., Rich J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
4
-
-
84861381332
-
Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells
-
Basile K.J., Abel E.V., Aplin A.E. Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells. Oncogene 2012, 31:2471-2479.
-
(2012)
Oncogene
, vol.31
, pp. 2471-2479
-
-
Basile, K.J.1
Abel, E.V.2
Aplin, A.E.3
-
5
-
-
0028224645
-
Mutator phenotype in human colorectal carcinoma cell lines
-
Bhattacharyya N.P., Skandalis A., Ganesh A., Groden J., Meuth M. Mutator phenotype in human colorectal carcinoma cell lines. Proceedings of the National Academy of Sciences of the United States of America 1994, 91:6319-6323.
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, pp. 6319-6323
-
-
Bhattacharyya, N.P.1
Skandalis, A.2
Ganesh, A.3
Groden, J.4
Meuth, M.5
-
6
-
-
0030741503
-
HMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents
-
Brown R., Hirst G.L., Gallagher W.M., McIlwrath A.J., Margison G.P., van der Zee A.G., et al. hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene 1997, 15:45-52.
-
(1997)
Oncogene
, vol.15
, pp. 45-52
-
-
Brown, R.1
Hirst, G.L.2
Gallagher, W.M.3
McIlwrath, A.J.4
Margison, G.P.5
van der Zee, A.G.6
-
7
-
-
7244232706
-
Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump
-
Burger H., van Tol H., Boersma A.W., Brok M., Wiemer E.A., Stoter G., et al. Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump. Blood 2004, 104:2940-2942.
-
(2004)
Blood
, vol.104
, pp. 2940-2942
-
-
Burger, H.1
van Tol, H.2
Boersma, A.W.3
Brok, M.4
Wiemer, E.A.5
Stoter, G.6
-
8
-
-
79956351015
-
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
-
Chaffer C.L., Brueckmann I., Scheel C., Kaestli A.J., Wiggins P.A., Rodrigues L.O., et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:7950-7955.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 7950-7955
-
-
Chaffer, C.L.1
Brueckmann, I.2
Scheel, C.3
Kaestli, A.J.4
Wiggins, P.A.5
Rodrigues, L.O.6
-
9
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman P.B., Hauschild A., Robert C., Haanen J.B., Ascierto P., Larkin J., et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. The New England Journal of Medicine 2011, 364:2507-2516.
-
(2011)
The New England Journal of Medicine
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
10
-
-
33847369455
-
Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line
-
Chen M.S., Woodward W.A., Behbod F., Peddibhotla S., Alfaro M.P., Buchholz T.A., et al. Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. Journal of Cell Science 2007, 120(Pt 3):468-4477.
-
(2007)
Journal of Cell Science
, vol.120
, Issue.PART 3
, pp. 468-4477
-
-
Chen, M.S.1
Woodward, W.A.2
Behbod, F.3
Peddibhotla, S.4
Alfaro, M.P.5
Buchholz, T.A.6
-
11
-
-
49949111381
-
Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells
-
Chen Y.C., Hsu H.S., Chen Y.W., Tsai T.H., How C.K., Wang C.Y., et al. Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells. PLoS One 2008, 3.
-
(2008)
PLoS One
, vol.3
-
-
Chen, Y.C.1
Hsu, H.S.2
Chen, Y.W.3
Tsai, T.H.4
How, C.K.5
Wang, C.Y.6
-
12
-
-
78650389774
-
Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
-
Chiou S.H., Wang M.L., Chou Y.T., Chen C.J., Hong C.F., Hsieh W.J., et al. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Research 2010, 70:10433-10444.
-
(2010)
Cancer Research
, vol.70
, pp. 10433-10444
-
-
Chiou, S.H.1
Wang, M.L.2
Chou, Y.T.3
Chen, C.J.4
Hong, C.F.5
Hsieh, W.J.6
-
13
-
-
78649436372
-
BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation
-
ra84
-
Corcoran R.B., Diase-Santagata D., Bergethon K., Iafrate A.J., Settleman J., Engelman J.A. BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation. Science Signaling 2010, 3:1-10. ra84.
-
(2010)
Science Signaling
, vol.3
, pp. 1-10
-
-
Corcoran, R.B.1
Diase-Santagata, D.2
Bergethon, K.3
Iafrate, A.J.4
Settleman, J.5
Engelman, J.A.6
-
14
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H., Bignell G.R., Cox C., Stephens P., Edkins S., Clegg S., et al. Mutations of the BRAF gene in human cancer. Nature 2002, 417:949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
15
-
-
0021918972
-
Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties
-
Davis R.L., Konopka J.B., Witte O.N. Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties. Molecular and Cellular Biology 1985, 5:204-213.
-
(1985)
Molecular and Cellular Biology
, vol.5
, pp. 204-213
-
-
Davis, R.L.1
Konopka, J.B.2
Witte, O.N.3
-
16
-
-
33846796149
-
Microbial phenotypic heterogeneity and antibiotic tolerance
-
Dhar N., McKinney J.D. Microbial phenotypic heterogeneity and antibiotic tolerance. Current Opinion in Microbiology 2007, 10:30-38.
-
(2007)
Current Opinion in Microbiology
, vol.10
, pp. 30-38
-
-
Dhar, N.1
McKinney, J.D.2
-
18
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
-
Duvic M., Talpur R., Ni X., Zhang C., Hazarika P., Kelly C., et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 2007, 109:31-39.
-
(2007)
Blood
, vol.109
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
Zhang, C.4
Hazarika, P.5
Kelly, C.6
-
19
-
-
45549093647
-
Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis
-
Eyler C.E., Rich J.N. Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis. Journal of Clinical Oncology 2008, 26:2839-2845.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 2839-2845
-
-
Eyler, C.E.1
Rich, J.N.2
-
21
-
-
32944468151
-
Mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy
-
Green H., Soderkvist P., Rosenberg P., Horvath G., Peterson C. mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy. Clinical Cancer Research 2006, 12:854-859.
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 854-859
-
-
Green, H.1
Soderkvist, P.2
Rosenberg, P.3
Horvath, G.4
Peterson, C.5
-
22
-
-
80755133415
-
EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells
-
Grovdal L.M., Kim J., Holst M.R., Knudsen S.L., Grandal M.V., Deurs B.V. EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells. Cell Signal 2012, 24:296-301.
-
(2012)
Cell Signal
, vol.24
, pp. 296-301
-
-
Grovdal, L.M.1
Kim, J.2
Holst, M.R.3
Knudsen, S.L.4
Grandal, M.V.5
Deurs, B.V.6
-
23
-
-
77949354563
-
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells
-
Halaban R., Zhang W., Bacchiocchi A., Cheng E., Parisi F., Ariyan S., Krauthammer M., McCusker J.P., Kluger Y., Sznol M. PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. Pigment Cell & Melanoma Research 2010, 23:190-200.
-
(2010)
Pigment Cell & Melanoma Research
, vol.23
, pp. 190-200
-
-
Halaban, R.1
Zhang, W.2
Bacchiocchi, A.3
Cheng, E.4
Parisi, F.5
Ariyan, S.6
Krauthammer, M.7
McCusker, J.P.8
Kluger, Y.9
Sznol, M.10
-
24
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
25
-
-
0037108047
-
Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo
-
Hanna L.A., Foreman R.K., Tarasenko I.A., Kessler D.S., Labosky P.A. Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes & Development 2002, 16:2650-2661.
-
(2002)
Genes & Development
, vol.16
, pp. 2650-2661
-
-
Hanna, L.A.1
Foreman, R.K.2
Tarasenko, I.A.3
Kessler, D.S.4
Labosky, P.A.5
-
26
-
-
74849109743
-
Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF
-
Heidorn S.J., Milagre C., Whittaker S., Nourry A., Niculescu-Duvas I., Dhomen N., et al. Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 2010, 140:209-221.
-
(2010)
Cell
, vol.140
, pp. 209-221
-
-
Heidorn, S.J.1
Milagre, C.2
Whittaker, S.3
Nourry, A.4
Niculescu-Duvas, I.5
Dhomen, N.6
-
27
-
-
78751648455
-
Hyperactivation of MEK-ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells
-
Kaplan F.M., Shao Y., Mayberry M.M., Aplin A.E. Hyperactivation of MEK-ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells. Oncogene 2011, 30:366-371.
-
(2011)
Oncogene
, vol.30
, pp. 366-371
-
-
Kaplan, F.M.1
Shao, Y.2
Mayberry, M.M.3
Aplin, A.E.4
-
28
-
-
84865859692
-
HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
-
Khan O., La Thangue N.B. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunology & Cell Biology 2011.
-
(2011)
Immunology & Cell Biology
-
-
Khan, O.1
La Thangue, N.B.2
-
29
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
Liu G., Yuan X., Zeng Z., Tunici P., Ng H., Abdulkadir I.R., et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Molecular Cancer 2006, 5.
-
(2006)
Molecular Cancer
, vol.5
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
-
30
-
-
55049125241
-
Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3
-
Liu Y., Labosky P.A. Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3. Stem Cells 2008, 26:2475-2484.
-
(2008)
Stem Cells
, vol.26
, pp. 2475-2484
-
-
Liu, Y.1
Labosky, P.A.2
-
31
-
-
34247109089
-
Histone deacetylase inhibitors for epigenetic therapy of cancer
-
Monneret C. Histone deacetylase inhibitors for epigenetic therapy of cancer. Anticancer Drugs 2007, 18:363-370.
-
(2007)
Anticancer Drugs
, vol.18
, pp. 363-370
-
-
Monneret, C.1
-
32
-
-
49649118852
-
Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma
-
Montagut C., Sharma S.V., Shioda T., McDermott U., Ulman M., Ulkus L.E., et al. Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma. Cancer Research 2008, 68:4853-4861.
-
(2008)
Cancer Research
, vol.68
, pp. 4853-4861
-
-
Montagut, C.1
Sharma, S.V.2
Shioda, T.3
McDermott, U.4
Ulman, M.5
Ulkus, L.E.6
-
33
-
-
0033215387
-
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
-
Murphy M., Ahn J., Walker K.K., Hoffman W.H., Evans R.M., Levine A.J., et al. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes & Development 1999, 13:2490-2501.
-
(1999)
Genes & Development
, vol.13
, pp. 2490-2501
-
-
Murphy, M.1
Ahn, J.2
Walker, K.K.3
Hoffman, W.H.4
Evans, R.M.5
Levine, A.J.6
-
34
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
Nazarian R., Shi H., Wang Q., Kong X., Koya R.C., Lee H., et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature 2010, 7326:973-977.
-
(2010)
Nature
, vol.7326
, pp. 973-977
-
-
Nazarian, R.1
Shi, H.2
Wang, Q.3
Kong, X.4
Koya, R.C.5
Lee, H.6
-
35
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
O'Brien S.G., Guilhot F., Larson R.A., Gathmann I., Baccarani M., Cervantes F., et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. The New England Journal of Medicine 2003, 348:994-1004.
-
(2003)
The New England Journal of Medicine
, vol.348
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
-
36
-
-
80052437758
-
New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer
-
Oxnard G.R., Arcila M.E., Chmielecki J., Ladanyi M., Miller V.A., Pao W. New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer. Clinical Cancer Research 2011, 17:5530-5537.
-
(2011)
Clinical Cancer Research
, vol.17
, pp. 5530-5537
-
-
Oxnard, G.R.1
Arcila, M.E.2
Chmielecki, J.3
Ladanyi, M.4
Miller, V.A.5
Pao, W.6
-
37
-
-
33845628507
-
A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal
-
Pan G., Li J., Zhou Y., Zheng H., Pei D. A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal. FASEB Journal 2006, 20:1730-1732.
-
(2006)
FASEB Journal
, vol.20
, pp. 1730-1732
-
-
Pan, G.1
Li, J.2
Zhou, Y.3
Zheng, H.4
Pei, D.5
-
38
-
-
14844353574
-
Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors
-
Peart M.J., Smyth G.K., van Laar R.K., Bowtell D.D., Richon V.M., Marks P.A., et al. Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:3697-3702.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 3697-3702
-
-
Peart, M.J.1
Smyth, G.K.2
van Laar, R.K.3
Bowtell, D.D.4
Richon, V.M.5
Marks, P.A.6
-
39
-
-
77953809781
-
Oncogenic RAS alters the global and gene-specific histone modification pattern during epithelial-mesenchymal transition in colorectal carcinoma cells
-
Pelaez I.M., Kalogeropoulou M., Ferraro A., Voulgari A., Pankotai T., Boros I., et al. Oncogenic RAS alters the global and gene-specific histone modification pattern during epithelial-mesenchymal transition in colorectal carcinoma cells. The International Journal of Biochemistry & Cell Biology 2010, 42:911-920.
-
(2010)
The International Journal of Biochemistry & Cell Biology
, vol.42
, pp. 911-920
-
-
Pelaez, I.M.1
Kalogeropoulou, M.2
Ferraro, A.3
Voulgari, A.4
Pankotai, T.5
Boros, I.6
-
41
-
-
83455254767
-
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
-
Poulikakos P.I., Persaud Y., Janakiraman M., Kong X., Ng C., Moriceau G., et al. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature 2011, 480:387-390.
-
(2011)
Nature
, vol.480
, pp. 387-390
-
-
Poulikakos, P.I.1
Persaud, Y.2
Janakiraman, M.3
Kong, X.4
Ng, C.5
Moriceau, G.6
-
42
-
-
77949732073
-
RAF inhibitors transactivate RAF dimers and ERK signaling in cells with wild-type BRAF
-
Poulikakos P.I., Zhang C., Bollag G., Shokat K.M., Rosen N. RAF inhibitors transactivate RAF dimers and ERK signaling in cells with wild-type BRAF. Nature 2010, 464:427-430.
-
(2010)
Nature
, vol.464
, pp. 427-430
-
-
Poulikakos, P.I.1
Zhang, C.2
Bollag, G.3
Shokat, K.M.4
Rosen, N.5
-
43
-
-
77956637544
-
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC
-
Rai K., Sarkar S., Broadbent T.J., Voas M., Grossmann K.F., Nadauld L.D., et al. DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell 2010, 142:930-942.
-
(2010)
Cell
, vol.142
, pp. 930-942
-
-
Rai, K.1
Sarkar, S.2
Broadbent, T.J.3
Voas, M.4
Grossmann, K.F.5
Nadauld, L.D.6
-
44
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
45
-
-
77952502408
-
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
-
Roesch A., Fukunaga-Kalabis M., Schmidt E.C., Zabierowski S.E., Brafford P.A., Vultur A., et al. A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 2010, 141:583-594.
-
(2010)
Cell
, vol.141
, pp. 583-594
-
-
Roesch, A.1
Fukunaga-Kalabis, M.2
Schmidt, E.C.3
Zabierowski, S.E.4
Brafford, P.A.5
Vultur, A.6
-
46
-
-
0030031866
-
Biological and molecular analysis of a low-grade recurrence of a glioblastoma multiforme
-
Scheck A.C., Shaprio J.R., Coons S.W., Norman S.A., Johnson P.C. Biological and molecular analysis of a low-grade recurrence of a glioblastoma multiforme. Clinical Cancer Research 1996, 2:187-199.
-
(1996)
Clinical Cancer Research
, vol.2
, pp. 187-199
-
-
Scheck, A.C.1
Shaprio, J.R.2
Coons, S.W.3
Norman, S.A.4
Johnson, P.C.5
-
47
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
-
Shah N.P., Nicoll J.M., Nagar B., Gorre M.E., Paquette R.L., Kuriyan J., et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2002, 2:117-125.
-
(2002)
Cancer Cell
, vol.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
Gorre, M.E.4
Paquette, R.L.5
Kuriyan, J.6
-
48
-
-
77955757007
-
Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells
-
Shao Y., Aplin A.E. Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells. Cancer Research 2010, 70:6670-6681.
-
(2010)
Cancer Research
, vol.70
, pp. 6670-6681
-
-
Shao, Y.1
Aplin, A.E.2
-
49
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma S.V., Lee D.Y., Li B., Quinlan M.P., Takahashi F., Maheswaran S., et al. A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 2010, 141:69-80.
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
-
50
-
-
0033535612
-
A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer
-
Strathdee G., MacKean M.J., Illand M., Brown R. A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer. Oncogene 1999, 18:2335-2341.
-
(1999)
Oncogene
, vol.18
, pp. 2335-2341
-
-
Strathdee, G.1
MacKean, M.J.2
Illand, M.3
Brown, R.4
-
51
-
-
78650008177
-
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
-
Villanueva J., Vultur A., Lee J.T., Somasundaram R., Fukunaga-Kalabis M., Cipolla A.K., et al. Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. Cancer Cell 2010, 18:683-695.
-
(2010)
Cancer Cell
, vol.18
, pp. 683-695
-
-
Villanueva, J.1
Vultur, A.2
Lee, J.T.3
Somasundaram, R.4
Fukunaga-Kalabis, M.5
Cipolla, A.K.6
-
52
-
-
80051625929
-
Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling
-
Wagle N., Emery C., Berger M.F., Davis M.J., Sawyer A., Pochanard P., et al. Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. Journal of Clinical Oncology 2011, 29:3085-3096.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 3085-3096
-
-
Wagle, N.1
Emery, C.2
Berger, M.F.3
Davis, M.J.4
Sawyer, A.5
Pochanard, P.6
-
53
-
-
0034210577
-
Mechanism of resistance to the ABL tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines
-
Weisberg E., Griffin J.D. Mechanism of resistance to the ABL tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines. Blood 2000, 95:3498-3505.
-
(2000)
Blood
, vol.95
, pp. 3498-3505
-
-
Weisberg, E.1
Griffin, J.D.2
-
54
-
-
77955602211
-
Gatekeeper mutations mediate resistance to BRAF-targeted therapies
-
35ra41
-
Whittaker S., Kirk R., Hayward R., Zambon A., Viros A., Cantarino N., et al. Gatekeeper mutations mediate resistance to BRAF-targeted therapies. Science Translational Medicine 2010, 2:1-10. 35ra41.
-
(2010)
Science Translational Medicine
, vol.2
, pp. 1-10
-
-
Whittaker, S.1
Kirk, R.2
Hayward, R.3
Zambon, A.4
Viros, A.5
Cantarino, N.6
-
55
-
-
33846287519
-
WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells
-
Woodward W.A., Chen M.S., Behbod F., Alfaro M.P., Buchholz T.A., Rosen J.M. WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:618-623.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 618-623
-
-
Woodward, W.A.1
Chen, M.S.2
Behbod, F.3
Alfaro, M.P.4
Buchholz, T.A.5
Rosen, J.M.6
|