Amputation induces stem cell mobilization to sites of injury during planarian regeneration

Development (Cambridge)

Volumn 139, Issue 19, 2012, Pages 3510-3520

  Guedelhoefer IV , O C ^a   Alvarado, Alejandro Sánchez ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Planaria; Regeneration; Stem cell migration; Stem cells; Stem cells recruitment; Tissue homeostasis; Tissue repair

Indexed keywords

AMPUTATION; ARTICLE; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; HOMEOSTASIS; HUMAN; HUMAN TISSUE; INJURY; NONHUMAN; PRIORITY JOURNAL; STEM CELL MOBILIZATION; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; TURBELLARIA;

AMPUTATION; ANIMALS; CELL MOVEMENT; FEMALE; MALE; PLANARIANS; RADIATION INJURIES, EXPERIMENTAL; REGENERATION; REPRODUCTION, ASEXUAL; SEXUALITY; STEM CELL TRANSPLANTATION; STEM CELLS; WOUNDS AND INJURIES;

PLANARIA; VERTEBRATA;

EID: 84865847909     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.082099     Document Type: Article

References (52)

1. Baguñà, J. (1976). Mitosis in the intact and regenerating planarian Dugesia mediterranea n.sp. II. Mitotic studies during regeneration, and a possible mechanism of blastema formation. J. Exp. Zool. 195, 65-79.
2. Baguñà, J., Saló, E. and Auladell, C. (1989). Regeneration and pattern formation in planarians. III. Evidence that neoblasts are totipotent stem cells and the source of blastema cells. Development 107, 77-86.
3. Bardeen, C. and Baetjer, F. (1904). The inhibitive action of the Roentgen rays on regeneration in planarians. J. Exp. Zool. 1, 191-195.
4. Barker, N., Bartfeld, S. and Clevers, H. (2010). Tissue-resident adult stem cell populations of rapidly self-renewing organs. Cell Stem Cell 7, 656-670.
5. Blanpain, C., Lowry, W. E., Geoghegan, A., Polak, L. and Fuchs, E. (2004). Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118, 635-648.
6. Brawley, C. and Matunis, E. (2004). Regeneration of male germline stem cells by spermatogonial dedifferentiation in vivo. Science 304, 1331-1334.
7. Cebrià, F. and Newmark, P. A. (2005). Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture. Development 132, 3691-3703.
8. Congdon, C. C. (1971). Bone marrow transplantation. Science 171, 1116-1124.
9. Daley, G. Q. and Scadden, D. T. (2008). Prospects for stem cell-based therapy. Cell 132, 544-548.
10. Dubois, F. (1949). Contribution á l'ètude de la migration des cellules de règènèration chez les Planaires dulcicoles. Bull. Biol. Fr. Belg. 83, 213-283.
11. Eisenhoffer, G. T., Kang, H. and Sánchez Alvarado, A. (2008). Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea. Cell Stem Cell 3, 327-339.
12. Fedecka-Bruner, B. (1965). Regeneration in Animals and Related Problems (ed. V. Kiortsis and H. A. L. Trampusch), pp. 185-192. Amsterdam, The Netherlands: North-Holland Publishing Company.
13. Flickinger, R. (1964). Isotopic evidence for a local origin of blastema cells in regenerating planarians. Exp. Cell Res. 34, 403-406.
14. Gurley, K. A., Elliott, S. A., Simakov, O., Schmidt, H. A., Holstein, T. W. and Sánchez Alvarado, A. (2010). Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response. Dev. Biol. 347, 24-39.
15. Hayashi, T., Asami, M., Higuchi, S., Shibata, N. and Agata, K. (2006). Isolation of planarian X-ray-sensitive stem cells by fluorescence-activated cell sorting. Dev. Growth Differ. 48, 371-380.
16. He, S., Iwashita, T., Buchstaller, J., Molofsky, A. V., Thomas, D. and Morrison, S. J. (2009). Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. Dev. Biol. 328, 257-272.
17. Kai, T. and Spradling, A. (2004). Differentiating germ cells can revert into functional stem cells in Drosophila melanogaster ovaries. Nature 428, 564-569.
18. Karp, J. M. and Leng Teo, G. S. (2009). Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell 4, 206-216.
19. Kato, K., Orii, H., Watanabe, K. and Agata, K. (1999). The role of dorsoventral interaction in the onset of planarian regeneration. Development 126, 1031-1040.
20. Kim, D., Hong, K. S. and Song, J. (2007). The present status of cell tracking methods in animal models using magnetic resonance imaging technology. Mol. Cells 23, 132-137.
21. Laird, D. J., De Tomaso, A. W. and Weissman, I. L. (2005). Stem cells are units of natural selection in a colonial ascidian. Cell 123, 1351-1360.
22. Laird, D. J., von Andrian, U. H. and Wagers, A. J. (2008). Stem cell trafficking in tissue development, growth, and disease. Cell 132, 612-630.
23. Lehnert, G. (1891). Beobachtung an Landplanarien. Arch. Naturgech. 1, 306-350.
24. Miller, W. and Kennedy, R. J. (1955). X-ray attenuation in lead, aluminum, and concrete in the range 275 to 525 kilovolts. Radiology 65, 920-925.
25. Molofsky, A. V., Slutsky, S. G., Joseph, N. M., He, S., Pardal, R., Krishnamurthy, J., Sharpless, N. E. and Morrison, S. J. (2006). Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443, 448-452.
26. Morrison, S. J. and Spradling, A. C. (2008). Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell 132, 598-611.
27. Newmark, P. A. and Sánchez Alvarado, A. (2000). Bromodeoxyuridine specifically labels the regenerative stem cells of planarians. Dev. Biol. 220, 142-153.
28. Newmark, P. A. and Sánchez Alvarado, A. (2002). Not your father's planarian: a classic model enters the era of functional genomics. Nat. Rev. Genet. 3, 210-219.
29. Ohlstein, B. and Spradling, A. (2007). Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science 315, 988-992.
30. Pearson, B. J. and Sánchez Alvarado, A. (2010). A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages. Development 137, 213-221.
31. Pearson, B. J., Eisenhoffer, G. T., Gurley, K. A., Rink, J. C., Miller, D. E. and Sánchez Alvarado, A. (2009). Formaldehyde-based whole-mount in situ hybridization method for planarians. Dev. Dyn. 238, 443-450.
32. Pellettieri, J., Fitzgerald, P., Watanabe, S., Mancuso, J., Green, D. R. and Sánchez Alvarado, A. (2010). Cell death and tissue remodeling in planarian regeneration. Dev. Biol. 338, 76-85.
33. Petersen, C. P. and Reddien, P. W. (2009). A wound-induced Wnt expression program controls planarian regeneration polarity. Proc. Natl. Acad. Sci. USA 106, 17061-17066.
34. Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S. and Marshak, D. R. (1999). Multilineage potential of adult human mesenchymal stem cells. Science 284, 143-147.
35. Reddien, P. W., Bermange, A. L., Murfitt, K. J., Jennings, J. R. and Sánchez Alvarado, A. (2005a). Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria. Dev. Cell 8, 635-649.
36. Reddien, P. W., Oviedo, N. J., Jennings, J. R., Jenkin, J. C. and Sánchez Alvarado, A. (2005b). SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells. Science 310, 1327-1330.
37. Reya, T., Morrison, S. J., Clarke, M. F. and Weissman, I. L. (2001). Stem cells, cancer, and cancer stem cells. Nature 414, 105-111.
38. Rietze, R. L., Valcanis, H., Brooker, G. F., Thomas, T., Voss, A. K. and Bartlett, P. F. (2001). Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 412, 736-739.
39. Saló, E. and Baguñà, J. (1985). Cell movement in intact and regenerating planarians. Quantitation using chromosomal, nuclear and cytoplasmic markers. J. Embryol. Exp. Morphol. 89, 57-70.
40. Salo, E. and Baguna, J. (1986). Stimulation of cellular proliferation and differentiation in the intact and regenerating planarian Dugesia(G) tigrina by the neuropeptide substance P. J. Exp. Zool. 237, 129-135.
41. Sánchez Alvarado, A., Newmark, P. A., Robb, S. M. and Juste, R. (2002). The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration. Development 129, 5659-5665.
42. Santos, F. (1929). Studies on transplantation in planaria. Biological Bulletin 57, 188-197.
43. Sherwood, R. I., Christensen, J. L., Conboy, I. M., Conboy, M. J., Rando, T. A., Weissman, I. L. and Wagers, A. J. (2004). Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell 119, 543-554.
44. Steele, V. and Lange, C. (1976). Effects of irradiation on stem cell response to differentiation inhibitors in the planarian Dugesia etrusca. Radiat. Res. 67, 21-29.
45. Stéphan-Dubois, F. and Lender, T. (1956). Corrélations humorales dans la régénération de planaires paludicoles. Ann. des Sc. Nat. Zool. 18, 223-230.
46. Stoner, D. S., Rinkevich, B. and Weissman, I. L. (1999). Heritable germ and somatic cell lineage competitions in chimeric colonial protochordates. Proc. Natl. Acad. Sci. USA 96, 9148-9153.
47. Verheyen, E. M. and Clevers, H. (2010). Wnts as self-renewal factors: mammary stem cells and beyond. Cell Stem Cell 6, 494-495.
48. Voskoboynik, A., Soen, Y., Rinkevich, Y., Rosner, A., Ueno, H., Reshef, R., Ishizuka, K. J., Palmeri, K. J., Moiseeva, E., Rinkevich, B. et al. (2008). Identification of the endostyle as a stem cell niche in a colonial chordate. Cell Stem Cell 3, 456-464.
49. Wagner, D. E., Wang, I. E. and Reddien, P. W. (2011). Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration. Science 332, 811-816.
50. Wenemoser, D. and Reddien, P. W. (2010). Planarian regeneration involves distinct stem cell responses to wounds and tissue absence. Dev. Biol. 344, 979-991.
51. Wolff, E. and Dubois, F. (1948). Sur la migration des cellules de régénération chez les planaires. Rev. Suisse Zool. 55, 218-227.
52. Zhong, J. F., Zhan, Y., Anderson, W. F. and Zhao, Y. (2002). Murine hematopoietic stem cell distribution and proliferation in ablated and nonablated bone marrow transplantation. Blood 100, 3521-3526.