메뉴 건너뛰기




Volumn 32, Issue 4, 2012, Pages 377-384

The Renin-Angiotensin-Aldosterone System in Podocytes

Author keywords

Aldosterone; Angiotensin II; Podocyte; Prorenin receptor

Indexed keywords

ALDOSTERONE; ALISKIREN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ANGIOTENSINOGEN; APOCYNIN; CALCIUM ION; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; HYDRALAZINE; LISINOPRIL; MINERALOCORTICOID RECEPTOR; PLACEBO; PRORENIN RECEPTOR; RENIN INHIBITOR; ROSIGLITAZONE; ROTENONE; SPIRONOLACTONE; TEMPOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

EID: 84865799862     PISSN: 02709295     EISSN: 15584488     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2012.06.009     Document Type: Article
Times cited : (60)

References (62)
  • 1
    • 75849147039 scopus 로고    scopus 로고
    • Relation between kidney function, proteinuria, and adverse outcomes
    • Hemmelgarn B.R., Manns B.J., Lloyd A., et al. Relation between kidney function, proteinuria, and adverse outcomes. JAMA 2010, 303:423-429.
    • (2010) JAMA , vol.303 , pp. 423-429
    • Hemmelgarn, B.R.1    Manns, B.J.2    Lloyd, A.3
  • 2
    • 79960392722 scopus 로고    scopus 로고
    • Combination inhibition of the renin-angiotensin system: is more better?
    • Krause M.W., Fonseca V.A., Shah S.V. Combination inhibition of the renin-angiotensin system: is more better?. Kidney Int 2011, 80:245-255.
    • (2011) Kidney Int , vol.80 , pp. 245-255
    • Krause, M.W.1    Fonseca, V.A.2    Shah, S.V.3
  • 3
    • 0034004798 scopus 로고    scopus 로고
    • Angiotensin II increases the intracellular calcium activity in podocytes of the intact glomerulus
    • Nitschke R., Henger A., Ricken S., et al. Angiotensin II increases the intracellular calcium activity in podocytes of the intact glomerulus. Kidney Int 2000, 57:41-49.
    • (2000) Kidney Int , vol.57 , pp. 41-49
    • Nitschke, R.1    Henger, A.2    Ricken, S.3
  • 4
    • 0030954434 scopus 로고    scopus 로고
    • Angiotensin II depolarizes podocytes in the intact glomerulus of the Rat
    • Gloy J., Henger A., Fischer K.G., et al. Angiotensin II depolarizes podocytes in the intact glomerulus of the Rat. J Clin Invest 1997, 99:2772-2781.
    • (1997) J Clin Invest , vol.99 , pp. 2772-2781
    • Gloy, J.1    Henger, A.2    Fischer, K.G.3
  • 5
    • 0025165780 scopus 로고
    • Enhanced angiotensin concentrations in specific intrarenal fluid compartments of the rat
    • Seikaly M.G., Arant B.S., Seney F.D. Enhanced angiotensin concentrations in specific intrarenal fluid compartments of the rat. J Clin Invest 1990, 86:1352-1357.
    • (1990) J Clin Invest , vol.86 , pp. 1352-1357
    • Seikaly, M.G.1    Arant, B.S.2    Seney, F.D.3
  • 6
    • 2542455650 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats
    • Hoffmann S., Podlich D., Hähnel B., Kriz W., Gretz N. Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats. J Am Soc Nephrol 2004, 15:1475-1487.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1475-1487
    • Hoffmann, S.1    Podlich, D.2    Hähnel, B.3    Kriz, W.4    Gretz, N.5
  • 7
    • 0030368533 scopus 로고    scopus 로고
    • Angiotensin II modulates glomerular capillary permselectivity in rat isolated perfused kidney
    • Lapinski R., Perico N., Remuzzi A., et al. Angiotensin II modulates glomerular capillary permselectivity in rat isolated perfused kidney. J Am Soc Nephrol 1996, 7:653-660.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 653-660
    • Lapinski, R.1    Perico, N.2    Remuzzi, A.3
  • 8
    • 69249209995 scopus 로고    scopus 로고
    • Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin
    • Huby A.C., Rastaldi M.P., Caron K., et al. Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin. PLoS One 2009, 4:e6721.
    • (2009) PLoS One , vol.4
    • Huby, A.C.1    Rastaldi, M.P.2    Caron, K.3
  • 9
    • 20844461826 scopus 로고    scopus 로고
    • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
    • Winn M.P., Conlon P.J., Lynn K.L., et al. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 2005, 308:1801-1804.
    • (2005) Science , vol.308 , pp. 1801-1804
    • Winn, M.P.1    Conlon, P.J.2    Lynn, K.L.3
  • 10
    • 79952344547 scopus 로고    scopus 로고
    • TRPC6 enhances angiotensin II-induced albuminuria
    • Eckel J., Lavin P.J., Finch E.A., et al. TRPC6 enhances angiotensin II-induced albuminuria. J Am Soc Nephrol 2011, 22:526-535.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 526-535
    • Eckel, J.1    Lavin, P.J.2    Finch, E.A.3
  • 11
    • 80053282316 scopus 로고    scopus 로고
    • Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway
    • Nijenhuis T., Sloan A.J., Hoenderop J.G., et al. Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway. Am J Pathol 2011, 179:1719-1732.
    • (2011) Am J Pathol , vol.179 , pp. 1719-1732
    • Nijenhuis, T.1    Sloan, A.J.2    Hoenderop, J.G.3
  • 12
    • 77950498008 scopus 로고    scopus 로고
    • Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-independent
    • Matsusaka T., Asano T., Niimura F., et al. Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-independent. Hypertension 2010, 55:967-973.
    • (2010) Hypertension , vol.55 , pp. 967-973
    • Matsusaka, T.1    Asano, T.2    Niimura, F.3
  • 13
    • 80054772222 scopus 로고    scopus 로고
    • Down-regulation of peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis
    • Hsu H.H., Hoffmann S., Di Marco G., et al. Down-regulation of peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis. Kidney Int 2011, 80:959-969.
    • (2011) Kidney Int , vol.80 , pp. 959-969
    • Hsu, H.H.1    Hoffmann, S.2    Di Marco, G.3
  • 14
    • 0032905987 scopus 로고    scopus 로고
    • Molecular biology and signaling of angiotensin receptors: an overview
    • Inagami T. Molecular biology and signaling of angiotensin receptors: an overview. J Am Soc Nephrol 1999, 10(Suppl 1):S2-S7.
    • (1999) J Am Soc Nephrol , vol.10 , Issue.SUPPL. 1
    • Inagami, T.1
  • 15
    • 0030693720 scopus 로고    scopus 로고
    • Expression of type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron
    • Bouby N., Hus-Citharel A., Marchetti J., et al. Expression of type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron. J Am Soc Nephrol 1997, 8:1658-1667.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 1658-1667
    • Bouby, N.1    Hus-Citharel, A.2    Marchetti, J.3
  • 16
    • 65249105407 scopus 로고    scopus 로고
    • Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis
    • Crowley S.D., Vasievich M.P., Ruiz P., et al. Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. J Clin Invest 2009, 119:943-953.
    • (2009) J Clin Invest , vol.119 , pp. 943-953
    • Crowley, S.D.1    Vasievich, M.P.2    Ruiz, P.3
  • 17
    • 33646590610 scopus 로고    scopus 로고
    • Efferent arterioles exclusively express the subtype 1A angiotensin receptor: functional insights from genetic mouse models
    • Harrison-Bernard L.M., Monjure C.J., Bivona B.J. Efferent arterioles exclusively express the subtype 1A angiotensin receptor: functional insights from genetic mouse models. Am J Physiol Renal Physiol 2006, 290:F1177-F1186.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Harrison-Bernard, L.M.1    Monjure, C.J.2    Bivona, B.J.3
  • 18
    • 58149161262 scopus 로고    scopus 로고
    • Angiotensin II upregulates RAGE expression on podocytes: role of AT2 receptors
    • Rüster C., Bondeva T., Franke S., et al. Angiotensin II upregulates RAGE expression on podocytes: role of AT2 receptors. Am J Nephrol 2009, 29:538-550.
    • (2009) Am J Nephrol , vol.29 , pp. 538-550
    • Rüster, C.1    Bondeva, T.2    Franke, S.3
  • 19
    • 33645577151 scopus 로고    scopus 로고
    • Functional expression of the renin-angiotensin system in human podocytes
    • Liebau M.C., Lang D., Böhm J., et al. Functional expression of the renin-angiotensin system in human podocytes. Am J Physiol Renal Physiol 2006, 290:F710-F719.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Liebau, M.C.1    Lang, D.2    Böhm, J.3
  • 20
    • 34248352591 scopus 로고    scopus 로고
    • Activation of the renin-angiotensin system within podocytes in diabetes
    • Yoo T.H., Li J.J., Kim J.J., et al. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int 2007, 71:1019-1027.
    • (2007) Kidney Int , vol.71 , pp. 1019-1027
    • Yoo, T.H.1    Li, J.J.2    Kim, J.J.3
  • 21
    • 67651085473 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli
    • Xu Z.G., Miao L.N., Cui Y.C., et al. Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli. Nephrol Dial Transplant 2009, 24:1744-1752.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1744-1752
    • Xu, Z.G.1    Miao, L.N.2    Cui, Y.C.3
  • 22
    • 0347992785 scopus 로고    scopus 로고
    • Activation of a local tissue angiotensin system in podocytes by mechanical strain
    • Durvasula R.V., Petermann A.T., Hiromura K., et al. Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int 2004, 65:30-39.
    • (2004) Kidney Int , vol.65 , pp. 30-39
    • Durvasula, R.V.1    Petermann, A.T.2    Hiromura, K.3
  • 23
    • 44949105469 scopus 로고    scopus 로고
    • Activation of a local renin angiotensin system in podocytes by glucose
    • Durvasula R.V., Shankland S.J. Activation of a local renin angiotensin system in podocytes by glucose. Am J Physiol Renal Physiol 2008, 294:F830-F839.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Durvasula, R.V.1    Shankland, S.J.2
  • 24
    • 77951104782 scopus 로고    scopus 로고
    • Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes
    • Sakoda M., Ichihara A., Kurauchi-Mito A., et al. Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes. Am J Hypertens 2010, 23:575-580.
    • (2010) Am J Hypertens , vol.23 , pp. 575-580
    • Sakoda, M.1    Ichihara, A.2    Kurauchi-Mito, A.3
  • 25
    • 78651259037 scopus 로고    scopus 로고
    • The renin inhibitor aliskiren attenuates high-glucose induced extracellular matrix synthesis and prevents apoptosis in cultured podocytes
    • Phillips L.M., Wang Y., Dai T., et al. The renin inhibitor aliskiren attenuates high-glucose induced extracellular matrix synthesis and prevents apoptosis in cultured podocytes. Nephron Exp Nephrol 2011, 118:e49-e59.
    • (2011) Nephron Exp Nephrol , vol.118
    • Phillips, L.M.1    Wang, Y.2    Dai, T.3
  • 26
    • 0345255806 scopus 로고    scopus 로고
    • Characterization of angiotensin II-receptor subtypes in podocytes
    • Wang L., Flannery P.J., Spurney R.F. Characterization of angiotensin II-receptor subtypes in podocytes. J Lab Clin Med 2003, 142:313-321.
    • (2003) J Lab Clin Med , vol.142 , pp. 313-321
    • Wang, L.1    Flannery, P.J.2    Spurney, R.F.3
  • 28
    • 78651293193 scopus 로고    scopus 로고
    • Angiotensin-(1-7) reduces proteinuria and diminishes structural damage in renal tissue of stroke-prone spontaneously hypertensive rats
    • Giani J.F., Muñoz M.C., Pons R.A., et al. Angiotensin-(1-7) reduces proteinuria and diminishes structural damage in renal tissue of stroke-prone spontaneously hypertensive rats. Am J Physiol Renal Physiol 2011, 300:F272-F282.
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Giani, J.F.1    Muñoz, M.C.2    Pons, R.A.3
  • 29
    • 0032923985 scopus 로고    scopus 로고
    • Induction of albuminuria in mice: synergistic effect of two monoclonal antibodies directed to different domains of aminopeptidase A
    • Mentzel S., van Son J.P., Dijkman H.B., Wetzels J.F., Assmann K.J. Induction of albuminuria in mice: synergistic effect of two monoclonal antibodies directed to different domains of aminopeptidase A. Kidney Int 1999, 55:1335-1347.
    • (1999) Kidney Int , vol.55 , pp. 1335-1347
    • Mentzel, S.1    van Son, J.P.2    Dijkman, H.B.3    Wetzels, J.F.4    Assmann, K.J.5
  • 30
    • 78049423569 scopus 로고    scopus 로고
    • Potential role of the (pro)renin receptor in cardiovascular and kidney diseases
    • Cousin C., Bracquart D., Contrepas A., Nguyen G. Potential role of the (pro)renin receptor in cardiovascular and kidney diseases. J Nephrol 2010, 23:508-513.
    • (2010) J Nephrol , vol.23 , pp. 508-513
    • Cousin, C.1    Bracquart, D.2    Contrepas, A.3    Nguyen, G.4
  • 31
    • 0036266596 scopus 로고    scopus 로고
    • The renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G., Delarue F., Burckle C., et al. The renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002, 109:1417-1427.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3
  • 32
    • 75649120756 scopus 로고    scopus 로고
    • Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling
    • Cruciat C.M., Ohkawara B., Acebron S.P., et al. Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science 2010, 327:459-463.
    • (2010) Science , vol.327 , pp. 459-463
    • Cruciat, C.M.1    Ohkawara, B.2    Acebron, S.P.3
  • 33
    • 77649171183 scopus 로고    scopus 로고
    • (Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation
    • Matavelli L.C., Huang J., Siragy H.M. (Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation. Clin Exp Pharmacol Physiol 2010, 37:277-282.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 277-282
    • Matavelli, L.C.1    Huang, J.2    Siragy, H.M.3
  • 34
    • 9644283069 scopus 로고    scopus 로고
    • Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin
    • Ichihara A., Hayashi M., Kaneshiro Y., et al. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J Clin Invest 2004, 114:1128-1135.
    • (2004) J Clin Invest , vol.114 , pp. 1128-1135
    • Ichihara, A.1    Hayashi, M.2    Kaneshiro, Y.3
  • 35
    • 75149152420 scopus 로고    scopus 로고
    • The biology of the (pro)renin receptor
    • Nguyen G., Muller D.N. The biology of the (pro)renin receptor. J Am Soc Nephrol 2010, 21:18-23.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 18-23
    • Nguyen, G.1    Muller, D.N.2
  • 36
    • 82655181484 scopus 로고    scopus 로고
    • Prorenin receptor is essential for podocyte autophagy and survival
    • Riediger F., Quack I., Qadri F., et al. Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol 2011, 22:2193-2202.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2193-2202
    • Riediger, F.1    Quack, I.2    Qadri, F.3
  • 37
    • 0035922443 scopus 로고    scopus 로고
    • Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease
    • Chrysostomou A., Becker G. Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease. N Engl J Med 2001, 345:925-926.
    • (2001) N Engl J Med , vol.345 , pp. 925-926
    • Chrysostomou, A.1    Becker, G.2
  • 38
    • 77953184636 scopus 로고    scopus 로고
    • Rationale and design of the Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial: a double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric effects of an aldosterone blocker in hypertensive patients with albuminuria
    • Ando K., Ohtsu H., Arakawa Y., et al. Rationale and design of the Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial: a double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric effects of an aldosterone blocker in hypertensive patients with albuminuria. Hypertens Res 2010, 33:616-621.
    • (2010) Hypertens Res , vol.33 , pp. 616-621
    • Ando, K.1    Ohtsu, H.2    Arakawa, Y.3
  • 39
    • 33846443625 scopus 로고    scopus 로고
    • Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1
    • Shibata S., Nagase M., Yoshida S., Kawachi H., Fujita T. Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 2007, 49:355-364.
    • (2007) Hypertension , vol.49 , pp. 355-364
    • Shibata, S.1    Nagase, M.2    Yoshida, S.3    Kawachi, H.4    Fujita, T.5
  • 40
    • 33744981628 scopus 로고    scopus 로고
    • Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker
    • Nagase M., Shibata S., Yoshida S., et al. Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. Hypertension 2006, 47:1084-1093.
    • (2006) Hypertension , vol.47 , pp. 1084-1093
    • Nagase, M.1    Shibata, S.2    Yoshida, S.3
  • 41
    • 79959238107 scopus 로고    scopus 로고
    • Mitochondrial dysfunction mediates aldosterone-induced podocyte damage: a therapeutic target of PPARã
    • Zhu C., Huang S., Yuan Y., et al. Mitochondrial dysfunction mediates aldosterone-induced podocyte damage: a therapeutic target of PPARã. Am J Pathol 2011, 178:2020-2031.
    • (2011) Am J Pathol , vol.178 , pp. 2020-2031
    • Zhu, C.1    Huang, S.2    Yuan, Y.3
  • 42
    • 57349168398 scopus 로고    scopus 로고
    • Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease
    • Shibata S., Nagase M., Yoshida S., et al. Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease. Nat Med 2008, 14:1370-1376.
    • (2008) Nat Med , vol.14 , pp. 1370-1376
    • Shibata, S.1    Nagase, M.2    Yoshida, S.3
  • 43
    • 33745058119 scopus 로고    scopus 로고
    • The podocyte's response to injury: role in proteinuria and glomerulosclerosis
    • Shankland S.J. The podocyte's response to injury: role in proteinuria and glomerulosclerosis. Kidney Int 2006, 69:2131-2147.
    • (2006) Kidney Int , vol.69 , pp. 2131-2147
    • Shankland, S.J.1
  • 44
    • 0036089691 scopus 로고    scopus 로고
    • Angiotensin II induces apoptosis in rat glomerular epithelial cells
    • Ding G., Reddy K., Kapasi A.A., et al. Angiotensin II induces apoptosis in rat glomerular epithelial cells. Am J Physiol Renal Physiol 2002, 283:F173-F180.
    • (2002) Am J Physiol Renal Physiol , vol.283
    • Ding, G.1    Reddy, K.2    Kapasi, A.A.3
  • 45
    • 79960972131 scopus 로고    scopus 로고
    • Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo
    • Wang L., Chang J.H., Paik S.Y., et al. Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo. Mol Endocrinol 2011, 25:1376-1386.
    • (2011) Mol Endocrinol , vol.25 , pp. 1376-1386
    • Wang, L.1    Chang, J.H.2    Paik, S.Y.3
  • 46
    • 79960936436 scopus 로고    scopus 로고
    • Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling
    • Vassiliadis J., Bracken C., Matthews D., et al. Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling. J Am Soc Nephrol 2011, 22:1453-1461.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1453-1461
    • Vassiliadis, J.1    Bracken, C.2    Matthews, D.3
  • 47
    • 79251577061 scopus 로고    scopus 로고
    • The regulation of autophagy-unanswered questions
    • Chen Y., Klionsky D.J. The regulation of autophagy-unanswered questions. J Cell Sci 2011, 124:161-170.
    • (2011) J Cell Sci , vol.124 , pp. 161-170
    • Chen, Y.1    Klionsky, D.J.2
  • 48
    • 77951169411 scopus 로고    scopus 로고
    • Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
    • Hartleben B., Gödel M., Meyer-Schwesinger C., et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 2010, 120:1084-1096.
    • (2010) J Clin Invest , vol.120 , pp. 1084-1096
    • Hartleben, B.1    Gödel, M.2    Meyer-Schwesinger, C.3
  • 50
    • 57049126587 scopus 로고    scopus 로고
    • The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells
    • Saleem M.A., Zavadil J., Bailly M., et al. The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells. Am J Physiol Renal Physiol 2008, 295:F959-F970.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Saleem, M.A.1    Zavadil, J.2    Bailly, M.3
  • 52
    • 56949105292 scopus 로고    scopus 로고
    • Mechanisms of angiotensin II signaling on cytoskeleton of podocytes
    • Hsu H.H., Hoffmann S., Endlich N., et al. Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. J Mol Med 2008, 86:1379-1394.
    • (2008) J Mol Med , vol.86 , pp. 1379-1394
    • Hsu, H.H.1    Hoffmann, S.2    Endlich, N.3
  • 53
    • 41849096667 scopus 로고    scopus 로고
    • Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis
    • Jia J., Ding G., Zhu J., et al. Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis. Am J Nephrol 2008, 28:500-507.
    • (2008) Am J Nephrol , vol.28 , pp. 500-507
    • Jia, J.1    Ding, G.2    Zhu, J.3
  • 54
    • 75149129615 scopus 로고    scopus 로고
    • Stretch reduces nephrin expression via an angiotensin II-AT(1)-dependent mechanism in human podocytes: effect of rosiglitazone
    • Miceli I., Burt D., Tarabra E., et al. Stretch reduces nephrin expression via an angiotensin II-AT(1)-dependent mechanism in human podocytes: effect of rosiglitazone. Am J Physiol Renal Physiol 2010, 298:F381-F390.
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Miceli, I.1    Burt, D.2    Tarabra, E.3
  • 55
    • 34447294574 scopus 로고    scopus 로고
    • Angiotensin II type 1 and type 2 receptors play opposite roles in regulating the barrier function of kidney glomerular capillary wall
    • Suzuki K., Han G.D., Miyauchi N., et al. Angiotensin II type 1 and type 2 receptors play opposite roles in regulating the barrier function of kidney glomerular capillary wall. Am J Pathol 2007, 170:1841-1853.
    • (2007) Am J Pathol , vol.170 , pp. 1841-1853
    • Suzuki, K.1    Han, G.D.2    Miyauchi, N.3
  • 56
    • 0035028772 scopus 로고    scopus 로고
    • Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis
    • Benigni A., Tomasoni S., Gagliardini E., et al. Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis. J Am Soc Nephrol 2001, 12:941-948.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 941-948
    • Benigni, A.1    Tomasoni, S.2    Gagliardini, E.3
  • 57
    • 33645459493 scopus 로고    scopus 로고
    • Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention
    • Macconi D., Abbate M., Morigi M., et al. Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention. Am J Pathol 2006, 168:1073-1085.
    • (2006) Am J Pathol , vol.168 , pp. 1073-1085
    • Macconi, D.1    Abbate, M.2    Morigi, M.3
  • 58
    • 77953683141 scopus 로고    scopus 로고
    • Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2
    • Hayashi K., Sasamura H., Ishiguro K., et al. Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2. Kidney Int 2010, 78:69-78.
    • (2010) Kidney Int , vol.78 , pp. 69-78
    • Hayashi, K.1    Sasamura, H.2    Ishiguro, K.3
  • 59
    • 69249158624 scopus 로고    scopus 로고
    • Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species
    • van den Hoven M.J., Waanders F., Rops A.L., et al. Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species. Nephrol Dial Transplant 2009, 24:2637-2645.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2637-2645
    • van den Hoven, M.J.1    Waanders, F.2    Rops, A.L.3
  • 60
    • 26044457674 scopus 로고    scopus 로고
    • Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy
    • Chen S., Lee J.S., Iglesias-de la Cruz M.C., et al. Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy. Nephrol Dial Transplant 2005, 20:1320-1328.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 1320-1328
    • Chen, S.1    Lee, J.S.2    Iglesias-de la Cruz, M.C.3
  • 61
    • 0347994931 scopus 로고    scopus 로고
    • Angiotensin II type 1-receptor mediated changes in heparan sulfate proteoglycans in human SV40 transformed podocytes
    • Brinkkoetter P.T., Holtgrefe S., van der Woude F.J., Yard B.A. Angiotensin II type 1-receptor mediated changes in heparan sulfate proteoglycans in human SV40 transformed podocytes. J Am Soc Nephrol 2004, 15:33-40.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 33-40
    • Brinkkoetter, P.T.1    Holtgrefe, S.2    van der Woude, F.J.3    Yard, B.A.4
  • 62
    • 33745821648 scopus 로고    scopus 로고
    • Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth
    • Liang X.B., Ma L.J., Naito T., et al. Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth. J Am Soc Nephrol 2006, 17:1886-1895.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1886-1895
    • Liang, X.B.1    Ma, L.J.2    Naito, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.