1H NMR-based metabonomic profiling of rat serum and urine to characterize the subacute effects of carbamate insecticide propoxur

Biomarkers

Volumn 17, Issue 6, 2012, Pages 566-574

  Liang, Yu Jie ^a   Wang, Hui Ping ^a   Long, Ding Xin ^a   Wu, Yi Jun ^a  

^a INSTITUTE OF ZOOLOGY   (China)

Author keywords

Metabonomics; NMR; Pesticide; Subacute; Toxicity

Indexed keywords

PROPOXUR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL ANIMAL; FATTY ACID OXIDATION; GLYCOLYSIS; KETOGENESIS; LIVER DYSFUNCTION; LIVER TOXICITY; MALE; MULTIVARIATE ANALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SERUM; URINALYSIS;

ANIMALS; BIOLOGICAL MARKERS; INSECTICIDES; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOME; METABOLOMICS; MULTIVARIATE ANALYSIS; OXIDATIVE STRESS; PATTERN RECOGNITION, AUTOMATED; PRINCIPAL COMPONENT ANALYSIS; PROPOXUR; RATS; RATS, WISTAR; TOXICITY TESTS, SUBACUTE;

ANIMALIA; RATTUS;

EID: 84865762775     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2012.704527     Document Type: Article

References (40)

1. Alam TM, Kathleen Alam M, Neerathilingam M, Volk DE, Sarkar S, Shakeel Ansari GA, Luxon BA. (2010). 1H NMR metabonomic study of rat response to tri-phenyl phosphate and tri-butyl phosphate exposure. Metabolomics 6:386-394.
2. Aliferis KA, Tokousbalides M. (2011). Metabolomics in pesticide research and development: Review and future perspectives. Metabolomics 7:35-53.
3. Beckonert OE, Bollard M, Ebbels TMD, Keun HC, Antti H, Holmes E, Lindon JC, Nicholson JK. (2003). NMR-based metabonomic toxicity classification: Hierarchical cluster analysis and k-nearestneighbour approaches. Anal Chim Acta 490:3-15.
4. Bradford BU, O'Connell TM, Han J, Kosyk O, Shymonyak S, Ross PK, Winnike J, Kono H, Rusyn I. (2008). Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease. Toxicol Appl Pharmacol 232:236-243.
5. Coen M, Lenz EM, Nicholson JK, Wilson ID, Pognan F, Lindon JC. (2003). An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy. Chem Res Toxicol 16:295-303.
6. El-Naggar Ael-R, Abdalla MS, El-Sebaey AS, Badawy SM. (2009). Clinical findings and cholinesterase levels in children of organophosphates and carbamates poisoning. Eur J Pediatr 168:951-956.
7. Gahelnabi M, Mousa H, Ali B. (2000). Comparative toxicity of the carbamate insecticides bendiocarb and propoxur in Nubian goats. Pakistan J Biol Sci 3:2193-2196.
8. Gupta S, Garg GR, Bharal N, Mediratta PK, Banerjee BD, Sharma KK. (2009). Reversal of propoxur-induced impairment of step-down passive avoidance, transfer latency and oxidative stress by piracetam and ascorbic acid in rats. Environ Toxicol Pharmacol 28:403-408.
9. Institóris L, Papp A, Siroki O, Banerjee BD, Dési I. (2002). Immuno- and neurotoxicological investigation of combined subacute exposure with the carbamate pesticide propoxur and cadmium in rats. Toxicology 178:161-173.
10. Institóris L, Siroki O, Undeger U, Basaran N, Banerjee BD, Dési I. (2001). Detection of the effects of repeated dose combined propoxur and heavy metal exposure by measurement of certain toxicological, haematological and immune function parameters in rats. Toxicology 163:185-193.
11. Iyaniwura TT. (1991). Relative inhibition of rat plasma and erythrocyte cholinesterases by pesticide combinations. Vet Hum Toxicol 33:166-168.
12. Lei R, Wu C, Yang B, Ma H, Shi C, Wang Q, Wang Q, Yuan Y, Liao M. (2008). Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: A rapid in vivo screening method for nanotoxicity. Toxicol Appl Pharmacol 232:292-301.
13. Lenz EM, Wilson ID. (2007). Analytical strategies in metabonomics. J Proteome Res 6:443-458.
14. Liao P, Wei L, Zhang X, Li X, Wu H, Wu Y, Ni J, Pei F. (2007). Metabolic profiling of serum from gadolinium chloride-treated rats by 1H NMR spectroscopy. Anal Biochem 364:112-121.
15. Lindon JC, Holmes E, Nicholson JK. (2001). Pattern recognition methods and applications in biomedical magnetic resonance. Prog Nucl Magn Reson Spectrosc 39:1-40.
16. Maran E, Fernández M, Barbieri P, Font G, Ruiz MJ. (2009). Effects of four carbamate compounds on antioxidant parameters. Ecotoxicol Environ Saf 72:922-930.
17. Maran E, Fernández-Franzón M, Font G, Ruiz MJ. (2010). Effects of aldicarb and propoxur on cytotoxicity and lipid peroxidation in CHO-K1 cells. Food Chem Toxicol 48:1592-1596.
18. Michael RP, Jonathan DC, Hannah MM, Russell JM, David AP, Julian LG. (2005). High Resolution 1H NMR-based Metabolomics Indicates a Neurotransmitter Cycling Deficit in Cerebral Tissue froma Mouse Model of Batten Disease. J Biol Chem 280:42508-42514.
19. Neerathilingam M, Volk DE, Sarkar S, Alam TM, Alam MK, Ansari GA, Luxon BA. (2010). 1H NMR-based metabonomic investigation of tributyl phosphate exposure in rats. Toxicol Lett 199:10-16. 574 Y. Liang et al. Biomarkers Nicholls AW, Holmes E, Lindon JC, Shockcor JP, Farrant RD, Haselden JN, Damment SJ, Waterfield CJ, Nicholson JK. (2001). Metabonomic investigations into hydrazine toxicity in the rat. Chem Res Toxicol 14:975-987.
20. Nicholson JK, Foxall PJ, Spraul M, Farrant RD, Lindon JC. (1995). 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. Anal Chem 67:793-811.
21. Nicholson JK, Kendall MD, Osborn D. (1983). Cadmium and mercury nephrotoxicity. Nature 304:633-635.
22. Nicholson JK, Lindon JC, Holmes E. (1999). 'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29:1181-1189.
23. Padilla S, Marshall RS, Hunter DL, Lowit A. (2007). Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. Toxicol Appl Pharmacol 219:202-209.
24. Nicholson JK, Lindon JC. (2008). Systems biology: Metabonomics. Nature 455:1054-1056.
25. Seth V, Banerjee BD, Bhattacharya A, Chakravorty AK. (2000). Lipid peroxidation, antioxidant enzymes, and glutathione redox system in blood of human poisoning with propoxur. Clin Biochem 33:683-685.
26. Seth V, Banerjee BD, Chakravorty AK. (2001). Lipid peroxidation, free radical scavenging enzymes, and glutathione redox system in blood of rats exposed to propoxur. Pestic Biochem Physiol 71:133-139.
27. Shukla Y, Baqar SM, Mehrotra NK. (1998). Carcinogenicity and co-carcinogenicity studies on propoxur in mouse skin. Food Chem Toxicol 36:1125-1130.
28. Siroki O, Undeger U, Institóris L, Nehéz M, Basaran N, Nagymajtényi L, Dési I. (2001). A study on geno- and immunotoxicological effects of subacute propoxur and pirimicarb exposure in rats. Ecotoxicol Environ Saf 50:76-81.
29. Solanky KS, Bailey NJ, Beckwith-Hall BM, Davis A, Bingham S, Holmes E, Nicholson JK, Cassidy A. (2003). Application of biofluid 1H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile. Anal Biochem 323:197-204.
30. Thiesen FV, Barros HM, Tannhauser M, Tannhauser SL. (1999). Behavioral changes and cholinesterase activity of rats acutely treated with propoxur. Jpn J Pharmacol 79:25-31.
31. Thompson HM. (1996). Interactions between pesticides; a review of reported effects and their implications for wildlife risk assessment. Ecotoxicology 5:59-81.
32. Tsang TM, Woodman B, McLoughlin GA, Griffin JL, Tabrizi SJ, Bates GP, Holmes E. (2006). Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by highresolution MAS 1H NMR spectroscopy. J Proteome Res 5:483-492.
33. Viant MR, Rosenblum ES, Tieerdema RS. (2003). NMR-based metabolomics: A powerful approach for characterizing the effects of environmental stressors on organism health. Environ Sci Technol 37:4982-4989.
34. Wang HP, Liang YJ, Long DX, Chen JX, Hou WY, Wu YJ. (2009). Metabolic profiles of serum from rats after subchronic exposure to chlorpyrifos and carbaryl. Chem Res Toxicol 22:1026-1033.
35. Wang HP, Liang YJ, Zhang Q, Long DX, Li W, Li L, Yang L, Yan XZ, Wu YJ. (2011). Changes in metabolic profiles of urine from rats following chronic exposure to anticholinesterase pesticides. Pestic Biochem Physiol 101:232-239.
36. Waters NJ, Holmes E, Waterfield CJ, Farrant RD, Nicholson JK. (2002). NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate. Biochem Pharmacol 64:67-77.
37. Waters NJ, Waterfield CJ, Farrant RD, Holmes E, Nicholson JK. (2005). Metabonomic deconvolution of embedded toxicity: Application to thioacetamide hepato- and nephrotoxicity. Chem Res Toxicol 18:639-654.
38. Wei L, Liao P, Wu H, Li X, Pei F, Li W, Wu Y. (2008). Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum. Toxicol Appl Pharmacol 227:417-429.
39. Wei L, Liao P, Wu H, Li X, Pei F, Li W, Wu Y. (2009). Metabolic profiling studies on the toxicological effects of realgar in rats by (1)H NMR spectroscopy. Toxicol Appl Pharmacol 234:314-325.
40. Wu H, Zhang X, Liao P, Li Z, Li W, Li X, Wu Y, Pei F. (2005). NMR spectroscopicbased metabonomic investigation on the acute biochemical effects induced by Ce(NO3)3 in rats. J Inorg Biochem 99:2151-2160.