The diagnostic value of water immersion skin wrinkling and Neuropads® in small fiber neuropathy

Clinical Neurophysiology

Volumn 123, Issue 10, 2012, Pages 2074-2079

  Datema, Mirjam ^a   Gert van Dijk, J ^a   Hoitsma, Elske ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Diaconessenhuis ^*  (Netherlands)

Author keywords

Diagnostic tests; Peripheral neuropathy; Sensitivity and specificity; Small fiber neuropathy; Sudomotor testing

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FEMALE; FOOT; HUMAN; MALE; MOISTURE; NEUROPAD; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SMALL FIBER NEUROPATHY; WATER IMMERSION; WATER IMMERSION SKIN WRINKLING; WRINKLE;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; IMMERSION; MALE; MIDDLE AGED; NEUROLOGIC EXAMINATION; POLYNEUROPATHIES; SENSITIVITY AND SPECIFICITY; WATER;

EID: 84865759137     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2012.01.026     Document Type: Article

References (25)

1. Bakkers M., Merkies I.S., Lauria G., Devigili G., Penza P., Lombardi R., et al. Intraepidermal nerve fiber density and its application in sarcoidosis. Neurology 2009, 6(73):1142-1148.
2. Clark C.V., Pentland B., Ewing D.J., Clarke B.F. Decreased skin wrinkling in diabetes mellitus. Diabetes Care 1984, 7:224-227.
3. England J.D., Gronseth G.S., Franklin G., Carter G.T., Kinsella L.J., Cohen J.A., et al. Evaluation of distal symmetric polyneuropathy: the role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review). Muscle Nerve 2009, 39:106-115.
4. Hoitsma E., De V.J., Drent M. The small fiber neuropathy screening list: construction and cross-validation in sarcoidosis. Respir Med 2011, 105:95-100.
5. Kamenov Z.A., Petrova J.J., Christov V.G. Diagnosis of diabetic neuropathy using simple somatic and a new autonomic (neuropad) tests in the clinical practice. Exp Clin Endocrinol Diabetes 2010, 118:226-233.
6. Lauria G., Cornblath D.R., Johansson O., McArthur J.C., Mellgren S.I., Nolano M., et al. EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy. Eur J Neurol 2005, 12:747-758.
7. Magda P., Latov N., Renard M.V., Sander H.W. Quantitative sensory testing: high sensitivity in small fiber neuropathy with normal NCS/EMG. J Peripher Nerv Syst 2002, 7:225-228.
8. Nebuchennykh M., Loseth S., Lindal S., Mellgren S.I. The value of skin biopsy with recording of intraepidermal nerve fiber density and quantitative sensory testing in the assessment of small fiber involvement in patients with different causes of polyneuropathy. J Neurol 2009, 256:1067-1075.
9. Papanas N., Giassakis G., Papatheodorou K., Papazoglou D., Monastiriotis C., Christakidis D., et al. Sensitivity and specificity of a new indicator test (Neuropad) for the diagnosis of peripheral neuropathy in type 2 diabetes patients: a comparison with clinical examination and nerve conduction study. J Diabetes Complications 2007, 21:353-358.
10. Papanas N., Papatheodorou K., Christakidis D., Papazoglou D., Giassakis G., Piperidou H., et al. Evaluation of a new indicator test for sudomotor function (Neuropad) in the diagnosis of peripheral neuropathy in type 2 diabetic patients. Exp Clin Endocrinol Diabetes 2005, 113:195-198.
11. Papanas N., Papatheodorou K., Papazoglou D., Christakidis D., Monastiriotis C., Maltezos E. Reproducibility of the new indicator test for sudomotor function (Neuropad) in patients with type 2 diabetes mellitus: short communication. Exp Clin Endocrinol Diabetes 2005, 113:577-581.
12. Papanas N, Papatheodorou K, Papazoglou D, Christakidis D, Monastiriotis C, Maltezos E. The new indicator test (Neuropad): a valuable diagnostic tool for small-fiber impairment in patients with type 2 diabetes. Diabetes Educ 2007;33:257-8, 260, 262.
13. Papanas N., Papatheodorou K., Papazoglou D., Kotsiou S., Maltezos E. A prospective study on the use of the indicator test Neuropad(R) for the early diagnosis of peripheral neuropathy in type 2 diabetes. Exp Clin Endocrinol Diabetes 2011, 119:122-125.
14. Quattrini C., Jeziorska M., Tavakoli M., Begum P., Boulton A.J., Malik R.A. The Neuropad test: a visual indicator test for human diabetic neuropathy. Diabetologia 2008, 51:1046-1050.
15. Santiago S., Ferrer T., Espinosa M.L. Neurophysiological studies of thin myelinated (A delta) and unmyelinated (C) fibers: application to peripheral neuropathies. Neurophysiol Clin 2000, 30:27-42.
16. Shy M.E., Frohman E.M., So Y.T., Arezzo J.C., Cornblath D.R., Giuliani M.J., et al. Quantitative sensory testing: report of the therapeutics and technology assessment subcommittee of the American academy of neurology. Neurology 2003, 25(60):898-904.
17. Spallone V., Morganti R., Siampli M., Fedele T., D'Amato C., Cacciotti L., et al. Neuropad as a diagnostic tool for diabetic autonomic and sensorimotor neuropathy. Diabet Med 2009, 26:686-692.
18. Stewart J.D., Low P.A., Fealey R.D. Distal small fiber neuropathy: results of tests of sweating and autonomic cardiovascular reflexes. Muscle Nerve 1992, 15:661-665.
19. Tavee J., Zhou L. Small fiber neuropathy: a burning problem. Cleve Clin J Med 2009, 76:297-305.
20. Teoh H.L., Chow A., Wilder-Smith E.P. Skin wrinkling for diagnosing small fibre neuropathy: comparison with epidermal nerve density and sympathetic skin response. J Neurol Neurosurg Psychiatry 2008, 79:835-837.
21. Tobin K., Giuliani M.J., Lacomis D. Comparison of different modalities for detection of small fiber neuropathy. Clin Neurophysiol 1999, 110:1909-1912.
22. Vinik A.I., Suwanwalaikorn S., Stansberry K.B., Holland M.T., McNitt P.M., Colen L.E. Quantitative measurement of cutaneous perception in diabetic neuropathy. Muscle Nerve 1995, 18:574-584.
23. Wilder-Smith E., Chow A. Water immersion and EMLA cause similar digit skin wrinkling and vasoconstriction. Microvasc Res 2003, 66:68-72.
24. Wilder-Smith E.P. Water immersion wrinkling-physiology and use as an indicator of sympathetic function. Clin Auton Res 2004, 14:125-131.
25. Wilder-Smith E.P., Guo Y., Chow A. Stimulated skin wrinkling for predicting intraepidermal nerve fibre density. Clin Neurophysiol 2009, 120:953-958.