Skin wrinkling for diagnosing small fibre neuropathy: Comparison with epidermal nerve density and sympathetic skin response

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 79, Issue 7, 2008, Pages 835-837

  Teoh, H L ^a   Chow, A ^b   Wilder Smith, E P ^b  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

EMLA;

ADULT; AGED; ARTICLE; CELL FUNCTION; CLINICAL ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ELECTROMYOGRAPHY; FEMALE; HUMAN; INTERMETHOD COMPARISON; MALE; NERVE CONDUCTION; NERVE FIBER; PRIORITY JOURNAL; SENSORY NEUROPATHY; SMALL FIBRE NEUROPATHY; SYMPATHETIC TONE; WRINKLE;

ADULT; AGED; COHORT STUDIES; EPIDERMIS; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS; NEURAL CONDUCTION; PARESTHESIA; PERIPHERAL NERVOUS SYSTEM DISEASES; PHYSICAL STIMULATION; SENSITIVITY AND SPECIFICITY; SKIN AGING; SKIN TESTS;

EID: 46249108824     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2007.140947     Document Type: Article

References (20)

1. Lacomis D. Small-fiber neuropathy. Muscle Nerve 2002;26:173-88.
2. De Sousa EA, Hays AP, Chin RL, et al. Characteristics of patients with sensory neuropathy diagnosed with abnormal small nerve fibres on skin biopsy. J Neurol Neurosurg Psychiatry 2006;77:983-5.
3. Periquet MI, Novak V, Collins MP, et al. Painful sensory neuropathy: prospective evaluation using skin biopsy. Neurology 1999;53:1641-7.
4. Shahani BT, Halperin JJ, Boulu P, et al. Sympathetic skin response: a method of assessing unmyelinated axon dysfunction in peripheral neuropathies. J Neurol Neurosurg Psychiatry 1984;47:536-42.
5. Lauria G, Cornblath DR, Johansson O, et al. EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy. Eur J Neurol 2005;12:747-58.
6. Bull C, Henry JA. Finger wrinkling as a test of autonomic function. BMJ 1977;1:551-2.
7. Wilder-Smith E, Chow A. Water immersion and EMLA cause similar digit skin wrinkling and vasoconstriction. Microvasc Res 2003;66:68-72.
8. Wilder-Smith EP, Chow A. Water-immersion wrinkling is due to vasoconstriction. Muscle Nerve 2003;27:307-11.
9. Wilder-Smith EP. Water immersion wrinkling-physiology and use as an indicator of sympathetic function. Clin Auton Res 2004;14:125- 31.
10. Mende B. [Failure to form wrinkles on the finger tips in the warm water test in lepromatous nerve damage]. (In German.) Z Hautkr 1985;60:1961-4.
11. Clark CV, Pentland B, Ewing DJ, et al. Decreased skin wrinkling in diabetes mellitus. Diabetes Care 1984;7:224-7.
12. Bril V, Nyunt M, Ngo M. Limits of the sympathetic skin response in patients with diabetic polyneuropathy. Muscle Nerve 2000;23:1427- 30.
13. Claus D, Mustafa C, Vogel W, et al. Assessment of diabetic neuropathy: definition of norm and discrimination of abnormal nerve function. Muscle Nerve 1993;16:757-68.
14. Cales L, Weber RA. Effect of water temperature on skin wrinkling. J Hand Surg [Am] 1997;22:747-9.
15. Anderson EA, Wallin BG, Mark AL. Dissociation of sympathetic nerve activity in arm and leg muscle during mental stress. Hypertension 1987;9:III114-19.
16. Wilder-Smith EP, Chow A. Comparison of a simple method for quantitation of intraepidermal nerve fibres with a standard image analysis method using hypothenar skin. J Neurol 2006;253:1011-15.
17. Novak V, Freimer ML, Kissel JT, et al. Autonomic impairment in painful neuropathy. Neurology 2001;56:861-8.
18. Hoitsma E, Marziniak M, Faber CG, et al. Small fibre neuropathy in sarcoidosis. Lancet 2002;359:2085-6.
19. Hilz MJ, Hecht MJ, Berghoff M, et al. Abnormal vasoreaction to arousal stimuli - an early sign of diabetic sympathetic neuropathy demonstrated by laser Doppler flowmetry. J Clin Neurophysiol 2000;17:419-25.
20. Zylka MJ, Rice FL, Anderson DJ. Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron 2005;45:17-25.