A prospective study on the use of the indicator test Neuropad® for the early diagnosis of peripheral neuropathy in type 2 diabetes

Experimental and Clinical Endocrinology and Diabetes

Volumn 119, Issue 2, 2011, Pages 122-125

  Papanas, N ^a   Papatheodorou, K ^a   Papazoglou, D ^a   Kotsiou, S ^a   Maltezos, E ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

diabetes mellitus; diabetic neuropathy; diagnosis; neuropad

Indexed keywords

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DEVICE; DIAGNOSTIC TEST; EARLY DIAGNOSIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC EXAMINATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

DIABETES MELLITUS, TYPE 2; DIABETIC NEUROPATHIES; EARLY DIAGNOSIS; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; INDICATORS AND REAGENTS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REAGENT KITS, DIAGNOSTIC; SENSITIVITY AND SPECIFICITY;

EID: 79651472784     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0030-1261934     Document Type: Article

References (31)

1. Boulton AJ, Vinik AI, Arezzo JC, et al. Diabetic neuropathies: a statement by the American Diabetes Assoc (Pubitemid 40434506)
2. Herman WH, Kennedy L. Underdiagnosis of peripheral neuropathy in type 2 diabetes. Diabetes Care 2005 28 1480-1481 (Pubitemid 40756716)
3. Kamenov ZA, Petrova JJ, Christov VG. Diagnosis of diabetic neuropathy using simple somatic and a new autonomic (neuropad) tests in the clinical practice. Exp Clin Endocrinol Diabetes 2010 118 226-233
4. Krarup C. An update on neurophysiological studies in neuropathy. Curr Opin Neurol 2003 16 603-612
5. Liatis S, Marinou K, Tentolouris N, et al. Usefulness of a new indicator test for the diagnosis of peripheral and autonomic neuropathy in patients with diabetes mellitus. Diabet Med 2007 24 1375-1380 (Pubitemid 350179435)
6. Low VA, Sandroni P, Fealey RD, et al. Detection of small-fiber neuropathy by sudomotor testing. Muscle Nerve 2006 34 57-61
7. Malik RA, Tesfaye S, Newrick PG, et al. Sural nerve pathology in diabetic patients with minimal but progressive neuropathy. Diabetologia 2005 48 578-585 (Pubitemid 40487306)
8. Papanas N, Papatheodorou K, Christakidis D, et al. Evaluation of a new indicator test for sudomotor function (Neuropad) in the diagnosis of peripheral neuropathy in type 2 diabetic patients. Exp Clin Endocrinol Diabetes 2005 113 195-198 (Pubitemid 40695323)
9. Papanas N, Papatheodorou K, Papazoglou D, et al. Reproducibility of the new indicator test for sudomotor function (Neuropad) in patients with type 2 diabetes mellitus: short communication. Exp Clin Endocrinol Diabetes 2005b 113 577-581 (Pubitemid 41810501)
10. Papanas N, Papatheodorou K, Papazoglou D, et al. The new indicator test (Neuropad): a valuable diagnostic tool for small-fiber impairment in patients with type 2 diabetes. Diabetes Educ 2007 33 257-258 260, 262
11. Papanas N, Giassakis G, Papatheodorou K, et al. Use of the new indicator test (Neuropad) for the assessment of the staged severity of neuropathy in type 2 diabetic patients. Exp Clin Endocrinol Diabetes 2007b 115 58-61 (Pubitemid 46293415)
12. Papanas N, Papatheodorou K, Papazoglou D, et al. A comparison of the new indicator test for sudomotor function (Neuropad) with the vibration perception threshold and the clinical examination in the diagnosis of peripheral neuropathy in subjects with type 2 diabetes. Exp Clin Endocrinol Diabetes 2008 116 135-138 (Pubitemid 351363386)
13. Papanas N, Ziegler D. New diagnostic tests for diabetic distal symmetric polyneuropathy. J Diabetes Complications 2009 Nov 5. [Epub ahead of print]
14. Provitera V, Nolano M, Caporaso G, et al. Evaluation of sudomotor function in diabetes using the dynamic sweat test. Neurology 2010 74 50-56
15. Quattrini C, Jeziorska M, Malik RA. Small fiber neuropathy in diabetes: clinical consequence and assessment. Int J Low Extrem Wounds 2004 3 16-21
16. Quattrini C, Jeziorska M, Tavakoli M, et al. The Neuropad test: a visual indicator test for human diabetic neuropathy. Diabetologia 2008 51 1046-1050
17. Rota E, Quadri R, Fanti E, et al. Electrophysiological findings of peripheral neuropathy in newly diagnosed type II diabetes mellitus. J Peripher Nerv Syst 2005 10 348-353
18. Smith AG, Ramachandran P, Tripp S, et al. Epidermal nerve innervation in impaired glucose tolerance and diabetes-associated neuropathy. Neurology 2001 57 1701-1704 (Pubitemid 33055493)
19. Spallone V, Morganti R, Siampli M, et al. Neuropad as a diagnostic tool for diabetic autonomic and sensorimotor neuropathy. Diabet Med 2009 26 686-692
20. Sumner CJ, Sheth S, Griffin JW, et al. The spectrum of neuropathy in diabetes and impaired glucose tolerance. Neurology 2003 60 108-111 (Pubitemid 36070653)
21. Sun PC, Lin HD, Jao SH, et al. Thermoregulatory sudomotor dysfunction and diabetic neuropathy develop in parallel in at-risk feet. Diabet Med 2008 25 413-418 (Pubitemid 351490114)
22. Tentolouris N, Achtsidis V, Marinou K, et al. Evaluation of the self-administered indicator plaster Neuropad for the diagnosis of neuropathy in diabetes. Diabetes Care 2008 31 236-237 (Pubitemid 351213327)
23. Tentolouris N, Marinou K, Kokotis P, et al. Sudomotor dysfunction is associated with foot ulceration in diabetes. Diabet Med 2009 26 302-305
24. Tentolouris N, Voulgari C, Liatis S, et al. Moisture status of the skin of the feet assessed by the visual test Neuropad correlates with foot ulceration in diabetes. Diabetes Care 2010 33 1112-1114
25. Valk GD, Nauta JJP, Strijers RLM, et al. Clinical examination versus neurophysiological examination in the diagnosis of diabetic polyneuropathy. Diabet Med 1992 9 716-721
26. Várkonyi T, Kempler P. Diabetic neuropathy: new strategies for treatment. Diabetes Obes Metab 2008 10 99-108
27. Yagihashi S, Yamagishi S, Wada R. Pathology and pathogenetic mechanisms of diabetic neuropathy: correlation with clinical signs and symptoms. Diabetes Res Clin Pract 2007 77 Suppl. 1 S184-S189 (Pubitemid 47212574)
28. Young MJ, Boulton AJM, McLeod AF, et al. A multicentre study of the prevalence of diabetic peripheral neuropathy in the United Kingdom hospital clinic population. Diabetologia 1993 36 150-154 (Pubitemid 23034314)
29. Zick R, Schäper T, Deeters U. Early detection of peripheral neuropathy. Measurement of perspiration in the diabetic foot. Klinikarzt 2003 32 192-194
30. Ziegler D, Siekierka-Kleiser E, Meyer B, et al. Validation of a novel screening device (NeuroQuick) for quantitative assessment of small fiber dysfunction as an early feature of diabetic polyneuropathy. Diabetes Care 2005 28 1169-1174 (Pubitemid 40616630)
31. Ziegler D, Mayer P, Mühlen H, et al. The natural history of somatosensory and autonomic nerve dysfunction in relation to glycaemic control during the first 5 years after diagnosis of Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1991 34 822-829