Metabotropic actions of the volatile anaesthetic sevoflurane increase protein kinase Mζ synthesis and induce immediate preconditioning protection of rat hippocampal slices

Journal of Physiology

Volumn 590, Issue 16, 2012, Pages 4093-4107

  Wang, Jun ^a   Meng, Fanli ^a,b   Cottrell, James E ^a   Sacktor, Todd C ^b   Kass, Ira S ^a,b  

^a Downstate Health Sciences University   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLOHEXIMIDE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE; PROTEIN KINASE M ZETA; RAPAMYCIN; SEVOFLURANE; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN PROTECTION; CELL HYPOXIA; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; HIPPOCAMPAL CA1 REGION; HYPERPOLARIZATION; ISCHEMIC PRECONDITIONING; LONG TERM MEMORY; LONG TERM POTENTIATION; MALE; MEMORY CONSOLIDATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE POTENTIAL; NEUROPHYSIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; RAT; TISSUE SLICE; UPREGULATION;

ANESTHETICS, INHALATION; ANIMALS; CYCLOHEXIMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HIPPOCAMPUS; IMMUNOSUPPRESSIVE AGENTS; ISCHEMIC PRECONDITIONING; METHYL ETHERS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITORS; RATS; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84865661890     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.233965     Document Type: Article

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